Donor cell-derived acute myeloid leukemia developing 14 months after matched unrelated bone marrow transplantation for chronic myeloid leukemia

Bone Marrow Transplantation

Volumn 28, Issue 7, 2001, Pages 705-707

  Hambach, L ^a   Eder, M ^a   Dammann, E ^a   Battmer, K ^a   Stucki, A ^a   Heil, G ^a   Ganser, A ^a   Hertenstein, B ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Acute myeloid leukemia; Donor cell leukemia; Matched unrelated bone marrow transplantation

Indexed keywords

BUSULFAN; CD34 ANTIGEN; CYCLOPHOSPHAMIDE; CYCLOSPORIN A; CYTARABINE; FLUDARABINE; FOSCARNET; GANCICLOVIR; METHOTREXATE; MITOXANTRONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; THYMOCYTE ANTIBODY; TOPOTECAN;

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; ARTICLE; BLAST CELL; BLAST CELL CRISIS; BONE MARROW TRANSPLANTATION; CASE REPORT; CELL SELECTION; CHIMERA; CHROMOSOME ANALYSIS; CHROMOSOME TRANSLOCATION; CHRONIC MYELOID LEUKEMIA; CYTOMEGALOVIRUS INFECTION; DONOR; FLUORESCENCE IN SITU HYBRIDIZATION; GRAFT VERSUS HOST REACTION; HEMATOPOIESIS; HLA MATCHING; HUMAN; LEUKEMIA REMISSION; MALE; MONONUCLEAR CELL; PHILADELPHIA 1 CHROMOSOME; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEX CHROMOSOME; T LYMPHOCYTE; VARIABLE NUMBER OF TANDEM REPEAT; WHOLE BODY RADIATION;

ADULT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; ANTIVIRAL AGENTS; BONE MARROW TRANSPLANTATION; COMBINED MODALITY THERAPY; CYCLOSPORINE; CYSTITIS; CYTARABINE; CYTOMEGALOVIRUS INFECTIONS; DNA, NEOPLASM; FEMALE; FOSCARNET; GANCICLOVIR; GRAFT VS HOST DISEASE; GRANULOCYTE COLONY-STIMULATING FACTOR; HISTOCOMPATIBILITY; HUMANS; HYDROXYUREA; IMMUNOSUPPRESSIVE AGENTS; INTERFERON-ALPHA; LEUKEMIA, MYELOCYTIC, ACUTE; LEUKEMIA, MYELOID, PHILADELPHIA-POSITIVE; MALE; METHOTREXATE; MITOXANTRONE; NEOPLASMS, SECOND PRIMARY; PREDNISOLONE; PROSTAGLANDINS; REMISSION INDUCTION; TOPOTECAN; TRANSPLANTATION CONDITIONING; TRANSPLANTATION, HOMOLOGOUS; VIDARABINE; WHOLE-BODY IRRADIATION;

EID: 0034748017     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1703225     Document Type: Article

References (13)

1. Donor cell leukemia: Report of a case occuring 11 years after allogeneic bone marrow transplantation and review of the literature
2. A Philadelphia chromosome positive acute lymphoblastic leukemia of donor origin after allogeneic bone marrow transplantation for chronic myelogenous leukemia in chronic phase
3. Leukaemic transformation of engrafted human marrow cells in vivo
4. Recurrence of Philadelphia chromosome-positive leukemia in donor cells after marrow transplantation for chronic granulocytic leukemia
5. Detection of chimeric BCR-ABL genes in acute lymphoblastic leukaemia by polymerase chain reaction
6. Nonmyeloablative transplants: Preclinical and clinical results
7. Misleading cytogenetic evidence of relapse in donor cells after allogeneic bone marrow transplantation corrected by fluorescent in situ hybridization
8. Inadvertent transmission of a donor's acute myeloid leukemia in bone marrow transplantation for chronic myeloid leukemia
9. In vivo leukemic transformation: Cytogenetic evidence of in vivo leukemic transformation of engrafted marrow cells
10. Cytogenetic evidence for recurrence of acute myelogenous leukemia after allogeneic bone marrow transplantation in donor hematopoietic cells
11. Donor cell leukemia developing six years after marrow grafting for acute leukemia
12. Detection of donor cell derived acute myelogenous leukemia in a patient transplanted for chronic myelogenous leukemia using fluorescence in situ hybridization
13. Donor cell leukemia after bone marrow transplantation for severe aplastic anemia