Contrast ultrasound imaging in focal liver lesions: Diagnostic value and guidelines;Échographie de contraste dans l'exploration des lésions focales hépatiques: Valeur diagnostique et recommandations

Journal de Radiologie

Volumn 85, Issue 5 II, 2004, Pages 680-689

  Tranquart, F ^a   Bleuzen, A ^a   Tchuenbou, J ^a  

^a CHU BRETONNEAU   (France)

Author keywords

Contrast agent; Echography; Hemangioma; Hepatocellular carcinoma; Liver; Metastasis

Indexed keywords

CONTRAST MEDIUM;

CONTRAST ENHANCEMENT; DIAGNOSTIC IMAGING; DIAGNOSTIC VALUE; HEMANGIOMA; HUMAN; IMAGE QUALITY; LIVER CELL CARCINOMA; LIVER INJURY; LIVER PARENCHYMA; LIVER SCINTISCANNING; LIVER TUMOR; PRACTICE GUIDELINE; REAL TIME ECHOGRAPHY; REVIEW; TISSUE CHARACTERIZATION; ULTRASOUND; ECHOGRAPHY; INCIDENTAL FINDING;

CARCINOMA, HEPATOCELLULAR; CONTRAST MEDIA; HUMANS; INCIDENTAL FINDINGS; LIVER NEOPLASMS; PRACTICE GUIDELINES;

EID: 16544377276     PISSN: 02210363     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0221-0363(04)97649-4     Document Type: Review

References (59)

1. Correas JM, Bridal L, Lesavre A, Mejean A, Claudon M, Helenon O. Ultrasound contrast agents: properties, principles of action, tolerance and artifacts. Eur Radiol 2001;11:1316-28.
2. Harvey CJ, Blomley MJ, Eckersley RJ, Cosgrove DO. Developments in ultrasound contrast media. Eur Radiol 2001;11:675-89.
3. Leen E, Horgan P. Ultrasound contrast agents for hepatic imaging with nonlinear modes. Curr Probl Diagn Radiol 2003;32:66-87.
4. Bauer A, Solbiati L, Weissman N. Ultrasound imaging with SonoVue: low mechanical index real-time imaging. Acad Radiol 2002;9:S282-4.
5. Leen E. The role of contrast-enhanced ultrasound in the characterisation of focal liver lesions. Eur Radiol 2001;11:E27-34.
6. Schneider M. Bubbles and microcirculatory disorders. Eur Radiol 2001;11:E1-5.
7. Solbiati L, Tonolini M, Cova L, Goldberg SN. The role of contrast-enhanced ultrasound in the detection of focal liver lesions. Eur Radiol 2001;11:E15-26.
8. Heckemann RA, Cosgrove DO, Blomley MJ, Eckersley RJ, Harvey CJ, Mine Y. Liver lesions: intermittent second-harmonic gray-scale US can increase conspicuity with microbubble contrast material-early experience. Radiology 2000;216:592-6.
9. Burns PN, Wilson SR, Simpson DH. Pulse inversion imaging of liver blood flow: improved method for characterizing focal masses with microbubble contrast. Invest Radiol 2000;35:58-71.
10. Lencioni R, Cioni D, Crocetti L et al. Ultrasound imaging of focal liver lesions with a second-generation contrast agent. Acad Radiol 2002;9:S371-4.
11. Quaia E, Stacul F, Bertolotto M, Locatelli M, Mucelli RP. Characterization of focal liver lesions with pulse inversion harmonic imaging (PIHI) using a second generation US contrast agent. Acad Radiol 2002;9:S376-9.
12. Harvey CJ, Albrecht T. Ultrasound of focal liver lesions. Eur Radiol 2001;11:1578-93.
13. Kim TK, Choi BY, Hong HS. Improved imaging of hepatic metastases with delayed pulse inversion harmonic imaging using a contrast agent SHU 508 A: preliminary study. Ultrasound Med Biol 2000;26:1439-44.
14. Albrecht T, Overberg A, Hoffmann CW et al. Characterization of focal liver lesions with phase inversion ultrasound during the late liver-specific phase of Levovist. Acad Radiol 2002;9:S375.
15. Hohmann J, Skrok J, Puls R, Albrecht T. Characterization of focal liver lesions with contrast-enhanced low MI real time ultrasound and SonoVue Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr. 2003;175:835-43.
16. Aube C, Lebigot J. Echographie de contraste: place dans le diagnostic et la caractérisation des tumeurs du foie. Gastroenterol Clin Biol 2003;S5:B63-B70.
17. Bertolotto M, Dalla Palma L, Quaia E, Locatelli M. Characterisation of unifocal liver lesions with pulse inversion harmonic imaging after Levovist injection: preliminary results. Eur Radiol 2000;10:1369-76.
18. Fracanzani AL, Burdick L, Borzio M et al. Contrast-enhanced Doppler ultrasonography in the diagnosis of hepatocellular carcinoma and premalignant lesions in patients with cirrhosis. Hepatology 2001;34:1109-12.
19. Choi BI, Kim TK, Han JK, Kim AY, Seong CK, Park SJ. Vascularity of hepatocellular carcinoma: assessment with contrast-enhanced second-harmonic versus conventional power Doppler US. Radiology 2000;214:381-6.
20. Furuse J, Nagase M, Ishii H, Yoshino M. Contrast enhancement patterns of hepatic tumours during the vascular phase using coded harmonic imaging and Levovist to differentiate hepatocellular carcinoma from other focal lesions. Br J Radiol 2003;76:385-92.
21. Numata K, Tanaka K, Kiba T et al. Contrast-enhanced, wide-band harmonic gray scale imaging of hepatocellular carcinoma: correlation with helical computed tomographic findings. J Ultrasound Med 2001;20:89-98.
22. Kitamura H, Kawasaki S, Nakajima K, Ota H. Correlation between microbubble contrast-enhanced color Doppler sonography and immunostaining for Kupffer cells in assessing the histopathologic grade of hepatocellular carcinoma: preliminary results. J Clin Ultrasound 2002;30:465-71.
23. Bartolotta TV, Midiri M, Scialpi M, Sciarrino E, Galia M, Lagalla R. Focal nodular hyperplasia in norma and fatty liver: a qualitative and quantitative evaluation with contrast ultrasound. Eur Radiol 2003; Epub.
24. von Herbay A, Vogt C, Haussinger D. Pulse inversion sonography in the early phase of the sonographic agent: differentiation between and malignant focal liver lesions. J Ultrasound Med 2002;21:1191-200.
25. Uggowitzer MM, Kugler C, Mischinger HJ et al. Echo-enhanced Doppler sonography of focal nodular hyperplasia. J Ultrasound Med 1999;18:445-51.
26. Quaia E, Bertolotto M, Dalla Palma L. Characterization of liver hemangiomas with pulse inversion harmonic imaging. Eur Radiol 2002;12:537-44.
27. Albrecht T, Blomley MJ. Characteristics of hepatic hemangiomas at contrast-enhanced harmonic US. Radiology 2001;220:269-70.
28. Dalla Palma L, Bertolotto M, Quaia E, Locatelli M. Detection of liver metastases with pulse inversion harmonic imaging: preliminary results. Eur Radiol 1999;9:S382-7.
29. Leen E. Ultrasound contrast harmonic imaging of abdominal organs. Semin Ultrasound CT MR 2001;22:11-24.
30. Harvey CJ, Blomley MJ, Eckersley RJ, Heckemann RA, Butler-Barnes J, Cosgrove DO. Pulse-inversion mode imaging of liver specific microbubbles: improved detection of subcentimetre metastases. Lancet 2000;355:807-8.
31. Harvey CJ, Blomley MJ, Eckersley RJ et al. Hepatic malignancies: improved detection with pulse-inversion US in late phase of enhancement with SH U 508A-early experience. Radiology 2000;216:903-8.
32. Wilson SR, Burns PN, Muradali D. Harmonic hepatic US with microbubble contrast agent: initial experience showing improved characterisation of haemangioma, hepatocellular carcinoma and metastasis. Radiology 2000;215:153-61.
33. Albrecht T, Blomley MJK, Burns PN et al. Improved detection of hepatic metastases with pulse inversion ultrasonography during the liver specific phase of SHU 508 A (Levovist)-multicentre study. Radiology 2003;227:361-70.
34. Leen E, Angerson WJ, Yarmenitis S et al. Multi-centre clinical study evaluating the efficacy of Sono Vue (BR1), a new ultrasound contrast agent in Doppler investigation of focal hepatic lesions. Eur J Radiol 2002;41:200-6.
35. Albrecht T, Hoffman CW, Schettler S et al. Improved detection of liver metastases with pulse inversion ultrasound during the late phase of Levovist®. Eur Radiol 2002;9:S236-9.
36. Bernatik T, Strobel D, Hahn EG, Becker D. Detection of liver metastases: comparison of contrast-enhanced wide-band harmonic imaging with conventional echography. J Ultrasound Med 2001;20:509-15.
37. Kim TK, Choi BI, Han JK, Hong HS, Park SH, Moon SG. Hepatic tumors: contrast agent-enhancement patterns with pulse-inversion harmonic US. Radiology 2000;216:411-7.
38. Blomley MJ, Albrecht T, Cosgrove DO et al. Stimulated acoustic emission to image a late liver and spleen-specific phase of Levovist in normal volunteers and patients with and without liver disease. Ultrasound Med Biol 1999;25:1341-52.
39. Albrecht T, Hoffmann CW, Schettler S, Overberg A, Ilg M, Wolf KJ. Improved detection of liver metastases with phase inversion imaging during the liver-specific phase of the ultrasound contrast agent levovist. Eur Radiol 1999;9:S388.
40. Quaia E, Bertolotto M, Forgacs B, Rimondini A, Locatelli M, Mucelli RP. Detection of liver metastases by pulse inversion harmonic imaging during Levovist late phase: comparison with conventional ultra-sound and helical CT in 160 patients. Eur Radiol. 2003;13:475-83.
41. Dill-Macky MJ, Burns PN, Khalili K, Wilson SR. Focal hepatic masses: enhancement patterns with SH U 508A and pulse-inversion US. Radiology 2002;222:95-102.
42. Blomley MJ, Sidhu PS, Cosgrove DO et al. Do different types of liver lesions differ in their uptake of the microbubble contrast agent SH U 508A in the late liver phase? Early experience. Radiology 2001;220:661-7.
43. Albrecht T, Hoffmann CW, Schmitz SA et al. Phase-inversion sonography during the liver-specific late phase of contrast enhancement: improved detection of liver metastases. Am J Roentgenol 2001;176:1191-8.
44. Albrecht T, Hoffmann CW, Schettler S et al. Improved detection of liver metastases with phase inversion ultrasound during the late phase of levovist. Acad Radiol 2002;9:S236-9.
45. Yucel C, Ozdemir H, Gurel S, Ozer S, Arac M. Detection and differential diagnosis of hepatic masses using pulse inversion harmonic imaging during the liver-specific late phase of contrast enhancement with Levovist. J Clin Ultrasound 2002;30:203-12.
46. Esteban JM, Molla MA, Tomas C, Maldonado L. Improved detection of liver metastases with contrast-enhanced wideband harmonic imaging: comparison with CT findings. Eur J Ultrasound 2002;15:119-26.
47. Del Fratre C, Zuiani C, Londero V et al. Comparing levovist-enhanced pulse inversion harmonic imaging and ferumoxides-enhanced MR imaging of hepatic metastases. Am J Roentgenol 2003;180:1339-46.
48. Strobel D, Raeker S, Martus P, Hahn EG, Becker D. Phase inversion harmonic imaging versus contrast-enhanced power Doppler sonography for the characterization of focal liver lesions. Int J Colorectal Dis 2003;18:63-72.
49. von Herbay A, Vogt C, Haussinger D. Late-phase pulse-inversion sonography using the contrast agent levovist: differentiation between benign and malignant focal lesions of the liver. Am J Roentgenol 2002;179:1273-9.
50. Kamel IR, Bluemke DA. Imaging evaluation of hepatocelullar carcinoma. J Vasc Interv Radiol 2002;13:S173-83.
51. Harvey CJ, Lim AK, Blomley MJ, Taylor-Robinson SD, Gedroyc WM, Cosgrove DO. Detection of an occult hepatocellular carcinoma using ultrasound with liver-specific microbubbles. Eur Radiol 2002;12:S70-3.
52. Meuwly JY, Schnyder P, Gudinchet F, Denys AL. Pulse-inversion harmonic imaging improves lesion conspicuity during US-guided biopsy. J Vasc Interv Radiol 2003;14:335-41.
53. Skjoldbye B, Pedersen MH, Struckmann J, Burcharth F, Larsen T. Improved detection and biopsy of solid liver lesions using pulse-inversion ultrasound scanning and contrast agent infusion. Ultrasound Med Biol 2002;28:439-44.
54. Numata K, Isozaki T, Ozawa Y et al. Percutaneous ablation therapy guided by contrast-enhanced sonography for patients with hepatocellular carcinoma. Am J Roentgenol 2003;180:143-9.
55. Cioni D, Lencioni R, Rossi S et al. Radiofrequency thermal ablation of hepatocellular carcinoma: using contrast-enhanced harmonic power Doppler sonography to assess treatment outcome. Am J Roentgenol 2001;177:783-8.
56. Livraghi T, Solbiati L, Meloni F, Ierace T, Goldberg SN, Gazelle GS. Percutaneous radiofrequency ablation of liver metastases in potential candidates for resection: the "test-of-time approach". Cancer 2003;97:3027-35.
57. Livraghi T, Solbiati L, Meloni MF, Gazelle GS, Halpern EF, Goldberg SN. Treatment of focal liver tumors with percutaneous radio-frequency ablation: complications encountered in a multicenter study. Radiology 2003;226:441-51.
58. Choi D, Lim HK, Kim SH et al. Hepatocellular carcinoma treated with percutaneous radio-frequency ablation: usefulness of power Doppler US with a microbubble contrast agent in evaluating therapeutic response-preliminary results. Radiology 2000;217:558-63.
59. Liu JB, Goldberg BB, Merton DA, Rawool NM, Needleman L, Forsberg F. The role of contrast-enhanced sonography for radiofrequency ablation of liver tumors. J Ultrasound Med 2001;20:517-23.