Nebulized budesonide to treat acute asthma in children

Jornal de Pediatria

Volumn 80, Issue 2, 2004, Pages 106-112

  Milani, Geórgia K M ^a   Rosário Filho, Nelson A ^a,b   Riedi, Carlos A ^a   Figueiredo, Bonald C ^a  

^a FEDERAL UNIVERSITY OF PARANÁ   (Brazil)

^b Departamento de Pediatria   (Brazil)

Author keywords

Acute asthma; Budesonide; Inhaled steroids; Prednisone

Indexed keywords

BUDESONIDE; HEMOGLOBIN; PLACEBO; PREDNISONE; SALBUTAMOL; BRONCHODILATING AGENT;

ACUTE DISEASE; ARTICLE; ASTHMA; CHILD; CHILDHOOD DISEASE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COUGHING; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG TOLERABILITY; FEMALE; HUMAN; MALE; NEBULIZATION; OXYGEN SATURATION; RANDOMIZED CONTROLLED TRIAL; SCORING SYSTEM; SINGLE DRUG DOSE; SYMPTOMATOLOGY; TABLET; VOMITING; ANALYSIS OF VARIANCE; NEBULIZER; PRESCHOOL CHILD; PROSPECTIVE STUDY; TREATMENT OUTCOME;

ACUTE DISEASE; ALBUTEROL; ANALYSIS OF VARIANCE; ASTHMA; BRONCHODILATOR AGENTS; BUDESONIDE; CHILD; CHILD, PRESCHOOL; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; NEBULIZERS AND VAPORIZERS; PLACEBO EFFECT; PROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 16544374176     PISSN: 00217557     EISSN: None     Source Type: Journal    
DOI: 10.2223/1148     Document Type: Article

References (31)

1. III Consenso Brasileiro no Manejo da Asma. J Pneumol. 2002;28 Suppl 1:1-28.
2. Barnes PJ. Molecular mechanisms of steroid action in asthma. J Allergy Clin Immunol. 1996;97:159-68.
3. Laitinen LA, Laitinen A. Remodeling of asthmatic airways by glucocorticosteroids. J Allergy Clin Immunol. 1996;97:153-8.
4. Johnson M. Pharmacodynamics and pharmacokinetics of inhaled glucocorticoids. J Allergy Clin Immunol. 1996;97:169-76.
5. Warner JO, Naspitz CK, Cropp GJA. Third International Pediatric Consensus Statement on the Management of Childhood Asthma. Pediatr Pulmonol. 1998;25:1-17.
6. De Blic J, Delacourt C, Le Bourgeois M, Mahut B, Ostinelli J, Caswell C, et al. Efficacy of nebulized budesonide in treatment of severe infantile asthma: a double-blind study. J Allergy Clin Immunol. 1996;98:14-20.
7. Scarfone RJ, Loiselle JM, Wiley II JF, Decker JM, Henretig FM, Joffe MD. Nebulized dexamethasone versus oral prednisone in the emergency treatment of asthmatic children. Ann of Emerg Med. 1995;26:480-86.
8. Levy ML, Stevenson C, Maslen T. Comparison of short courses of oral prednisolone and fluticasone propionate in the treatment of adults with acute exacerbations of asthma in primary care. Thorax. 1996;51:1087-92.
9. Schuh S, Johnson DW, Callahan S, Canny G, Levison H. Efficacy of frequent nebulized ipratropium bromide added to frequent high-dose albuterol therapy in severe childhood asthma. J Pediatr. 1995;126:639-45.
10. Morgenstern GK, Rosário NA, Ferrari FP, Cat R, Carreiro JE, Caleffe LG. Uso de escore clínico para a avaliação da gravidade da crise de asma. J Pediatr (Rio). 1998;74:455-60.
11. Tal A, Levy N, Bearman JE. Methylprednisolone therapy for acute asthma in infants and toddlers: a controlled clinical trial. Pediatrics. 1990;86:350-6.
12. Scarfone RJ, Fuchs SM, Nager AL, Shane SA. Controlled trial of oral prednisone in the Emergency Department treatment of children with acute asthma. Pediatrics. 1993;92:513-18.
13. Storr J, Barrell E, Barry W, Lenney W, Hatcher G. Effect of a single dose of prednisolone in acute childhood asthma. Lancet. 1987;18:879-82.
14. Kattan M, Gurwitz D, Levison H. Corticosteroids in status asthmaticus. J Pediatr. 1980;96:596-9.
15. McFadden Jr ER. Inhaled glucocorticoids and acute asthma. Therapeutic breakthrough or nonspecific effect? Am J Respir Crit Care Med. 1998;157:677-8.
16. Kerem E, Tibshirani R, Canny G, Bentur L, Reisman J, Schuh S, et al. Predicting the need for hospitalization in children with acute asthma. Chest. 1990;98:1355-61.
17. Fischl MA, Pitchenik A, Gardner LB. An index predicting relapse and need for hospitalization in patients with acute bronchial asthma. N Engl J Med. 1981;305:783-9.
18. Holmgren D, Sixt R. Effects of salbutamol inhalations on transcutaneous blood gases in children during the acute asthmatic attack: from acute deterioration to recovery. Acta Paediatr. 1994;83:515-19.
19. Sano F, Naspitz CK, Solé D, Pedersen S. Nebulized budesonide in the treatment of acute episodes of wheeze in infants. J Allergy Clin Immunol. 1998;101:S9.
20. Pierson WE, Bierman CW, Kelley VC. A double-blind trial of corticosteroid therapy in status asthmaticus. Pediatrics. 1974;54:282-8.
21. Younger RE, Gerber PS, Herrod HG, Cohen RM, Crawford LV. Intravenous methylprednisolone efficacy in status asthmaticus in childhood. Pediatrics. 1986;80:225-30.
22. Fanta CH, Rossing TH, McFadden ER Jr. Glucocorticoids in acute asthma. A critical controlled trial. Am J Med. 1983;74:845-51.
23. Volovitz B, Bentur L, Finkelstein Y, Mansour Y, Shalitin S, Nussinovitch M, et al. Effectiveness and safety of inhaled corticosteroids in controlling acute asthma attacks in children who were treated in the emergency department: a controlled comparative study with oral prednisolone. J Allergy Clin Immunol. 1998;102:605-9.
24. Mitchell CA, Alpers JH, Morton SM, Raggoley CJ. Comparison of nebulized budesonide with oral prednisolone in the treatment of severe acute asthma. Eur Respir J. 1995;8:490A.
25. Devidayal, Singhi S, Kurnar L, Jayshree M. Efficacy of nebulized budesonide compared to oral prednisolone in acute bronchial asthma. Acta Paediatr. 1999;88:835-40.
26. Curtis P. Comparison of prednisolone and nebulised budesonide in acute asthma in children: a pilot study. Eur Resp J. 1995;8:S470.
27. Matthews EE, Curtis PD, Mclain BI, Morris LS, Turbitt ML. Nebulized budesonide versus oral steroid in severe exacerbations of childhood asthma. Acta Paediatr. 1999;88:841-3.
28. Nuhõglu Y, Bahceciler NN, Barlan IB, Mujdat-Basaran M. The effectiveness of high-dose inhaled budesonide therapy in the treatment of acute asthma exacerbation in children. Ann Allergy Asthma Immunol. 2001;86:318-22
29. Schuh S, Reisman J, Alshehri M, Dupuis A, Corey M, Arseneault R. A comparison of inhaled fluticasone and oral prednisone for children with severe acute asthma. N Engl J Med. 2000;343:689-94.
30. Sung L, Osmond MH, Klassen TP. Randomized controlled trial of inhaled budesonide as an adjunct to oral prednisone in acute asthma. Acad Emerg Med. 1998;5:209-13.
31. Hendeles L, Sherman J. Are inhaled corticosteroids effective for acute exacerbation of asthma in children. J Pediatr. 2003;142(2 Suppl):26-33.