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1
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5344272596
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Navigating toward fetal and maternal health; the challenge of treating epilepsy in pregnancy
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Tomson T, Perucca E, Battino D. Navigating toward fetal and maternal health; the challenge of treating epilepsy in pregnancy. Epilepsia 2004; 45:1171-1175. This is an editorial with a brief review of the most significant cohort studies conducted during the past 5 years on congenital malformations and use of AEDs.
-
(2004)
Epilepsia
, vol.45
, pp. 1171-1175
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-
Tomson, T.1
Perucca, E.2
Battino, D.3
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2
-
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0032747235
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Antiepileptic drug regimens and major congenital abnormalities in the offspring
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Samren EB, van Duijn CM, Christiaens GC, et al. Antiepileptic drug regimens and major congenital abnormalities in the offspring. Ann Neurol 1999; 46:739-746.
-
(1999)
Ann Neurol
, vol.46
, pp. 739-746
-
-
Samren, E.B.1
Van Duijn, C.M.2
Christiaens, G.C.3
-
3
-
-
0032132828
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Pregnancies of women with epilepsy: A population-based study in Iceland
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Olafsson E, Hallgrimsson JT, Hauser WA, et al. Pregnancies of women with epilepsy: a population-based study in Iceland. Epilepsia 1998; 39:887-892.
-
(1998)
Epilepsia
, vol.39
, pp. 887-892
-
-
Olafsson, E.1
Hallgrimsson, J.T.2
Hauser, W.A.3
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4
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0033066533
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Congenital malformations due to antiepileptic drugs
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Kaneko S, Battino D, Andermann E, et al. Congenital malformations due to antiepileptic drugs. Epilepsy Res 1999; 33:145-158.
-
(1999)
Epilepsy Res
, vol.33
, pp. 145-158
-
-
Kaneko, S.1
Battino, D.2
Andermann, E.3
-
5
-
-
1542315305
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Malformation rates in children of women with untreated epilepsy: A meta-analysis
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Fried S, Kozer E, Nulman I, et al. Malformation rates in children of women with untreated epilepsy: a meta-analysis. Drug Saf 2004; 27:197-202. This meta-analysis of 10 studies suggests that drug treatment rather than epilepsy per se is associated with an increased risk for birth defects.
-
(2004)
Drug Saf
, vol.27
, pp. 197-202
-
-
Fried, S.1
Kozer, E.2
Nulman, I.3
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6
-
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0037236359
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Epilepsy and pregnancy: Report of an Epilepsy Research Foundation Workshop
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Barrett C, Richens A. Epilepsy and pregnancy: report of an Epilepsy Research Foundation Workshop. Epilepsy Res 2003; 52:147-187. This is a comprehensive summary of a recent international workshop covering most issues of relevance for this topic.
-
(2003)
Epilepsy Res
, vol.52
, pp. 147-187
-
-
Barrett, C.1
Richens, A.2
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7
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0141706894
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Gabapentin exposure in human pregnancy: Results from the Gabapentin Pregnancy Registry
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Montouris G. Gabapentin exposure in human pregnancy: results from the Gabapentin Pregnancy Registry. Epilepsy Behav 2003; 4:310-317.
-
(2003)
Epilepsy Behav
, vol.4
, pp. 310-317
-
-
Montouris, G.1
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8
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0042420527
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Levetiracetam monotherapy during pregnancy: A case series
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Long L. Levetiracetam monotherapy during pregnancy: a case series. Epilepsy Behav 2003; 4:447-448.
-
(2003)
Epilepsy Behav
, vol.4
, pp. 447-448
-
-
Long, L.1
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9
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2442554134
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The AED (antiepileptic drug) pregnancy registry: A 6-year experience
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Holmes LB, Wyszynski DF, Lieberman E. The AED (antiepileptic drug) pregnancy registry: a 6-year experience. Arch Neurol 2004; 61:673-678. This is the first full-length publication from NAREP, identifying phenobarbital to be associated with an increased risk for birth defects.
-
(2004)
Arch Neurol
, vol.61
, pp. 673-678
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Holmes, L.B.1
Wyszynski, D.F.2
Lieberman, E.3
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10
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0037465533
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Major malformations in offspring of women with epilepsy
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Kaaja E, Kaaja R, Hiilesmaa V. Major malformations in offspring of women with epilepsy. Neurology 2003; 60:575-579. This well designed, single-centre cohort study of birth defects in offspring of women with epilepsy found a higher malformation rate among infants exposed to antiepileptic drugs in utero than in offspring of untreated women with epilepsy, but it did not reveal any differences between drugs.
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(2003)
Neurology
, vol.60
, pp. 575-579
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Kaaja, E.1
Kaaja, R.2
Hiilesmaa, V.3
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13
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10744224908
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Epilepsy and pregnancy: Lamotrigine as main drug used
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Sabers A, Dam M, A-Rogvi-Hansen B, et al. Epilepsy and pregnancy: lamotrigine as main drug used. Acta Neurol Scand 2004; 109:9-13.
-
(2004)
Acta Neurol Scand
, vol.109
, pp. 9-13
-
-
Sabers, A.1
Dam, M.2
A-Rogvi-Hansen, B.3
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14
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1242314854
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Major malformations in infants exposed to antiepileptic drugs in utero, with emphasis on carbamazepine and valproic acid: A nation-wide, population-based register study
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Wide K, Winbladh B, Kallen B. Major malformations in infants exposed to antiepileptic drugs in utero, with emphasis on carbamazepine and valproic acid: a nation-wide, population-based register study. Acta Paediatr 2004; 93:174-176. This population-based, nationwide study utilizing the Swedish Medical Birth Registry reported significantly higher malformation rates with valproic acid than with carbamazepine.
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(2004)
Acta Paediatr
, vol.93
, pp. 174-176
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Wide, K.1
Winbladh, B.2
Kallen, B.3
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15
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0141670265
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The Australian registry of anti-epileptic drugs in pregnancy: Experience after 30 months
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Vajda FJ, O'Brien TJ, Hitchcock A, et al. The Australian registry of anti-epileptic drugs in pregnancy: experience after 30 months. J Clin Neurosci 2003; 10:543-549.
-
(2003)
J Clin Neurosci
, vol.10
, pp. 543-549
-
-
Vajda, F.J.1
O'Brien, T.J.2
Hitchcock, A.3
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16
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19644401012
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U.K. Epilepsy and pregnancy group
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Russell AJ, Craig JJ, Morrison P, et al. U.K. Epilepsy and pregnancy group. Epilepsia 2004; 45:1467. A summary update report from the UK Epilepsy and Pregnancy Register is presented.
-
(2004)
Epilepsia
, vol.45
, pp. 1467
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Russell, A.J.1
Craig, J.J.2
Morrison, P.3
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17
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7944226728
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EURAP: An international registry of antiepileptic drugs and pregnancy
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Tomson T, Battino D, Bonizzoni E, et al. EURAP: an international registry of antiepileptic drugs and pregnancy. Epilepsia 2004; 45:1463-1464. This is a summary update report from EURAP.
-
(2004)
Epilepsia
, vol.45
, pp. 1463-1464
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-
Tomson, T.1
Battino, D.2
Bonizzoni, E.3
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18
-
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19644400695
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North American Antiepileptic Drug Pregnancy Registry
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Holmes LB, Wyszynski DF. North American Antiepileptic Drug Pregnancy Registry. Epilepsia 2004; 45:1465. This is a summary update report from NAREP.
-
(2004)
Epilepsia
, vol.45
, pp. 1465
-
-
Holmes, L.B.1
Wyszynski, D.F.2
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19
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19644401289
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Australian pregnancy registry of women taking antiepileptic drugs
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Vajda F, Lander C, O'Brien T, et al. Australian pregnancy registry of women taking antiepileptic drugs. Epilepsia 2004; 45:1466. A summary update report from the Australian Pregnancy Registry is presented.
-
(2004)
Epilepsia
, vol.45
, pp. 1466
-
-
Vajda, F.1
Lander, C.2
O'Brien, T.3
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20
-
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0035849144
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The teratogenicity of anticonvulsant drugs
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Holmes LB, Harvey EA, Coull BA, et al. The teratogenicity of anticonvulsant drugs. N Engl J Med 2001; 344:1132-1138.
-
(2001)
N Engl J Med
, vol.344
, pp. 1132-1138
-
-
Holmes, L.B.1
Harvey, E.A.2
Coull, B.A.3
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21
-
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0036799783
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Preliminary results on pregnancy outcomes in women using lamotrigine
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Tennis P, Eldridge RR. Preliminary results on pregnancy outcomes in women using lamotrigine. Epilepsia 2002; 43:1161-1167.
-
(2002)
Epilepsia
, vol.43
, pp. 1161-1167
-
-
Tennis, P.1
Eldridge, R.R.2
-
22
-
-
19644401206
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The International Lamotrigine Pregnancy Registry update for the Epilepsy Foundation
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Cunnington MC. The International Lamotrigine Pregnancy Registry update for the Epilepsy Foundation. Epilepsia 2004; 45:1468. A summary update report from the manufacturer's lamotrigine pregnancy registry.
-
(2004)
Epilepsia
, vol.45
, pp. 1468
-
-
Cunnington, M.C.1
-
23
-
-
84921704273
-
Common antiepileptic drugs in pregnancy in women with epilepsy (Cochrane review)
-
Chichester, UK: John Wiley & Sons, Ltd
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Adab N, Tudur SC, Vinten J, et al. Common antiepileptic drugs in pregnancy in women with epilepsy (Cochrane review). In: The Cochrane Library. Chichester, UK: John Wiley & Sons, Ltd; Issue 3, 2004. This is a systematic critical review of the literature on potential adverse effects of AED exposure in utero on postnatal neurodevelopment. The conclusion was that the majority of studies were of limited quality and that there was little evidence about which drugs carry more risk than others.
-
(2004)
The Cochrane Library
, Issue.3
-
-
Adab, N.1
Tudur, S.C.2
Vinten, J.3
-
25
-
-
7244257375
-
The longer term outcome of children born to mothers with epilepsy
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Adab N, Kini U, Vinten J, et al. The longer term outcome of children born to mothers with epilepsy. J Neurol Neurosurg Psychiatry 2004; 75:1575-1583. This is a thorough re-evaluation of a previous retrospective cohort suggesting that frequent tonic-clonic seizures during pregnancy and exposure to valproic acid in utero are associated with lower verbal IQ in the children. The retrospective design, low rate of participation and small numbers call for caution in Interpretation of the data.
-
(2004)
J Neurol Neurosurg Psychiatry
, vol.75
, pp. 1575-1583
-
-
Adab, N.1
Kini, U.2
Vinten, J.3
-
26
-
-
9144257236
-
Normal intelligence in children with prenatal exposure to carbamazepine
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Gaily E, Kantola-Sorsa E, Hiilesmaa V, et al. Normal intelligence in children with prenatal exposure to carbamazepine. Neurology 2004; 62: 28-32. This well designed prospective study of long-term postnatal effects of exposure to AEDs in utero indicates lack of adverse effects of carbamazepine. Only few exposures to valproic acid are included.
-
(2004)
Neurology
, vol.62
, pp. 28-32
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Gaily, E.1
Kantola-Sorsa, E.2
Hiilesmaa, V.3
-
27
-
-
0142199908
-
Psychomotor development and general movements in offspring of women with epilepsy and anticonvulsant therapy
-
Parisi P, Francia A, Vanacore N, et al. Psychomotor development and general movements in offspring of women with epilepsy and anticonvulsant therapy. Early Hum Dev 2003; 74:97-108.
-
(2003)
Early Hum Dev
, vol.74
, pp. 97-108
-
-
Parisi, P.1
Francia, A.2
Vanacore, N.3
-
28
-
-
0042536455
-
Psychomotor development in children exposed in utero to benzodiazepines, antidepressants, neuroleptics, and anti-epileptics
-
Mortensen JT, Olsen J, Larsen H, et al. Psychomotor development in children exposed in utero to benzodiazepines, antidepressants, neuroleptics, and anti-epileptics. Eur J Epidemiol 2003; 18:769-771.
-
(2003)
Eur J Epidemiol
, vol.18
, pp. 769-771
-
-
Mortensen, J.T.1
Olsen, J.2
Larsen, H.3
-
29
-
-
0037308662
-
Effects of phenobarbital and multiple-dose corticosteroids on developmental outcome at age 7 years
-
Thorp JA, O'Connor M, Belden B, et al. Effects of phenobarbital and multiple-dose corticosteroids on developmental outcome at age 7 years. Obstet Gynecol 2003; 101:363-373. This is a secondary analysis of a randomized double-blind study of antenatal phenobarbital in women at risk for premature delivery. IQ at 7 years of age was similar among children exposed to phenobarbital compared with placebo.
-
(2003)
Obstet Gynecol
, vol.101
, pp. 363-373
-
-
Thorp, J.A.1
O'Connor, M.2
Belden, B.3
-
30
-
-
0028799430
-
In utero exposure to phenobarbital and intelligence deficits in adult men
-
Reinisch JM, Sanders SA, Mortensen EL, Rubin DB. In utero exposure to phenobarbital and intelligence deficits in adult men. JAMA 1995; 274: 1518-1525.
-
(1995)
JAMA
, vol.274
, pp. 1518-1525
-
-
Reinisch, J.M.1
Sanders, S.A.2
Mortensen, E.L.3
Rubin, D.B.4
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