Assessment of the distribution of radiolabelled non-ionic multilamellar surfactant microvesicles following topical application to canine skin biopsies: A preliminary study

Journal of Drug Delivery Science and Technology

Volumn 15, Issue 2, 2005, Pages 183-185

  Barthe, N ^a   Jasmin, P ^b   Brouillaud, B ^a   Guinez, C ^c   Coulon, P ^d   Gatto, H ^b  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b Virbac SA   (France)

^c Centre Condorcet   (France)

^d Biospace Mesures   (France)

Author keywords

Dog; Penetration; Radio imaging; Skin; Spherulites; Topical therapy

Indexed keywords

CARBON 14; DRUG CARRIER; NONIONIC SURFACTANT; PALMITIC ACID; SPHERULITE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; CONTROLLED STUDY; DERMIS; DOG; EPIDERMIS; FROZEN SECTION; HAIR FOLLICLE; IMAGE ANALYSIS; IMAGING SYSTEM; ISOTOPE LABELING; NONHUMAN; RADIOACTIVITY; SIGNAL DETECTION; SKIN BIOPSY; SKIN PENETRATION; TISSUE DISTRIBUTION; TOPICAL DRUG ADMINISTRATION;

EID: 16444364238     PISSN: 11571489     EISSN: None     Source Type: Journal    
DOI: 10.1016/s1773-2247(05)50024-8     Document Type: Article

References (7)

1. GULIKT., DEDIEU J.C., ROUX D., DEGERT C., LAVERSANNE R. - Freeze-fracture electron microscopy of sheared lamellar phase - Langmuir, 12, 4668, 1996.
2. MIGNET N., BRUN A., DEGERT C., DELORD B., ROUX D., LAVERSANNE R., FRANÇOIS J.C. - The Spherulites: a promising carrier for oligonucleotide delivery - Nucleic Acids Research, 28, 16, 3134-3142, 2000.
3. Active principle carriers containing non-ionic surfactants, and uses thereof, particularly in food, cosmetics and pharmaceuticals. - International PCT patent WO 97/00623, owned by Capsulis, France, 9 January 1997.
4. Method for making a product adhere to a surface. - International PCT patent WO 98/46199, owned by Capsulis, France, 10 April 1998.
5. DROZ B., BOUTEILLE M. - Techniques in radioautography - Journal de Microscopie et de Biologie Cellulaire, 27, 2-3, 1976.
6. LANIECE P., CHARON Y., CARDONA A. et al. - A new high resolution radio imager for the quantitative analysis of radiolabelled molecules in tissue section - Journal of Neuroscience Methods, 86, 1-5, 1998.
7. BETZ G., IMBODEN R., IMANIDIS G. - Interaction of liposome formulations with human skin in vitro - Int. J. Pharm., 229, 117-129, 2001.