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Volumn 28, Issue 1, 2004, Pages 11-15

Simultaneous Determination of Isoline and Its Two Major Metabolites Using High-Performance Liquid Chromatography

Author keywords

[No Author keywords available]

Indexed keywords

BISLINE; BISLINE LACTONE; ISOLINE; MICROSOME ENZYME; PYRROLIZIDINE ALKALOID; UNCLASSIFIED DRUG;

EID: 1642580602     PISSN: 01464760     EISSN: None     Source Type: Journal    
DOI: 10.1093/jat/28.1.11     Document Type: Article
Times cited : (9)

References (12)
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    • R.J. Huxable. Human health implication of pyrrolizidine alkaloids and herbs containing them. In Toxicants of Plant Origin, Vol. 1, Alkaloids, P.R. Cheeke, Ed. CRC Press, Boca Raton, FL, 1989, pp 41-86.
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    • Huxable, R.J.1
  • 4
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    • Isolation and identification of a pyrrolic glutathione conjugate metabolite of the pyrrolizidine alkaloid monocrotaline
    • W.L. Michael, D. Morin, A.D. Jones, H.J. Segall, and D.W. Wilson. Isolation and identification of a pyrrolic glutathione conjugate metabolite of the pyrrolizidine alkaloid monocrotaline, Toxicol. Lett. 51: 321-329 (1990).
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    • D.E. Williams, R.L. Reed, B. Kedzierski, G.A. Dannan, F.P. Guengerich, and D.R. Buhler, Bioactivation and detoxication of the pyrrolizidine alkaloid senecionine by cytochrome P-450 enzymes in rat liver. Drug Metab. Dispos. 17: 387-392 (1989).
    • (1989) Drug Metab. Dispos. , vol.17 , pp. 387-392
    • Williams, D.E.1    Reed, R.L.2    Kedzierski, B.3    Dannan, G.A.4    Guengerich, F.P.5    Buhler, D.R.6
  • 6
    • 0033669269 scopus 로고    scopus 로고
    • Characterization of rat liver microsomal metabolites of clivorine, an hepatotoxic otonecine-type pyrrolizidine alkaloid
    • G. Lin, Y.Y. Cui, and E.M. Hawes. Characterization of rat liver microsomal metabolites of clivorine, an hepatotoxic otonecine-type pyrrolizidine alkaloid. Drug Metab. Dispos. 28: 1475-1483 (2000).
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  • 7
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    • Hydrolysis rates of pyrrolizidine alkaloids derived from Seneciojacobaea
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.