Serum osteoprotegerin but not receptor activator of NF-κB ligand correlates with Larsen score in rheumatoid arthritis

Annals of the Rheumatic Diseases

Volumn 63, Issue 2, 2004, Pages 216-217

  Skoumal, M ^a,e   Kolarz, G ^a   Woloszczuk, W ^b   Hawa, G ^c   Klingler, A ^d  

^a Institut fur Rheumatologie   (Austria)

^b LUDWIG BOLTZMANN INSTITUTE FOR LUNG VASCULAR RESEARCH   (Austria)

^c Biomedica Medizinprodukte GmbH C   (Austria)

^d UNIVERSITY HOSPITAL INNSBRUCK   (Austria)

^e Rheumasonderkrankenanstalt der SVA   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; OSTEOPROTEGERIN; STEROID;

ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME IMMUNOASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; HUMAN; LOW DRUG DOSE; MALE; MEASUREMENT; OSTEOPOROSIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RHEUMATOID ARTHRITIS; SCORING SYSTEM; STATISTICAL SIGNIFICANCE; UPREGULATION;

ADULT; ARTHRITIS, RHEUMATOID; CARRIER PROTEINS; FEMALE; GLYCOPROTEINS; HUMANS; JOINTS; MALE; MEMBRANE GLYCOPROTEINS; MIDDLE AGED; OSTEOPROTEGERIN; RANK LIGAND; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, TUMOR NECROSIS FACTOR;

EID: 1642580527     PISSN: 00034967     EISSN: None     Source Type: Journal    
DOI: 10.1136/ard.2002.004507     Document Type: Article

References (10)

1. Simonet WS, Lacey DL, Dunstan CR, Kelley M, Chang MS, Luthy R, et al. Osteoprotegerin: A novel secreted protein involved in the regulation of bone density. Cell 1997;89:309-19.
2. Itonaga I, Fujikawa Y, Sabokar A, Murray DW, Athanasou NA. Rheumatoid arthritis synovial macrophage-osteoclast differentiation is osteoprotegerin ligand-dependent. J Pathol 2000;192:97-104.
3. Burgess TL, Qian Y, Kaufman S, Ring BD, Van G, Capparelli C, et al. The ligand for osteoprotegerin (OPGL) directly activates mature osteoclasts. J Cell Biol 1999;145:527-38.
4. Hofbauer LC, Heufelder AC. Role of receptor activator of nuclear factor -κB ligand and osteoprotegerin in bone cell biology. J Mol Med 2001;79:243-53.
5. Takayanagi H, Iizuka H, Juji T, Nakagawa T, Yamamoto A, Miyazaki T, et al. Involvement of receptor activator of nuclear factor-κB ligand osteoclast differentiation factor in osteoclastogenesis from synoviocytes in rheumatoid arthritis. Arthritis Rheum 2000;43:259-69.
6. Kudlacek S, Schneider B, Woloszczuk W, Pietschmann P, Willvonseder R. Serum levels of osteoprotegerin increase with age in healthy adult population. Bone 2003;32:681-6.
7. Gravallese EM, Manning C, Tsay A, et al. Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factor. Arthritis Rheum 2000;43:250-8.
8. Kolarz G, Schödl CH, Skoumal M, Woloszczuk W, Wottawa A. Osteoprotegerin serum levels in rheumatoid arthritis: J Mineralstoffwechsel, (in press).
9. Haynes DR, Crotti TN, Loric M, Bain GI, Atkins GJ, Findlay DM. Osteoprotegerin and receptor activator of nuclear factor-κB ligand (RANKL) regulate osteoclast formation by cells in the human rheumatoid arthritic joint. Rheumatology (Oxford) 2001;40:623-30.
10. Haynes DR, Barg E, Crotti TN, Holding C, Weedon H, Atkins GJ, et al. Osteoprotegerin expression in synovial tissue from patients with rheumatoid arthritis, spondylorthropathies and osteoarthritis and normal controls. 2003;42:123-34.