Prenatal Exposure to Carbon Monoxide Affects Postnatal Cellular Electrophysiological Maturation of the Rat Heart: A Potential Substrate for Arrhythmogenesis in Infancy

Circulation

Volumn 109, Issue 3, 2004, Pages 419-423

  Sartiani, Laura ^a   Cerbai, Elisabetta ^a   Lonardo, Giuseppe ^a   DePaoli, Petra ^a   Tattoli, Maria ^b   Cagiano, Raffaele ^b   Carratù, Maria Rosaria ^b   Cuomo, Vincenzo ^c   Mugelli, Alessandro ^a,d  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF BARI   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d Dept of Preclin/Clin Pharmacol ^*  (Italy)

Author keywords

Carbon monoxide; Death, sudden, infant; Electrophysiology; Ion channels; Smoking

Indexed keywords

CARBON MONOXIDE; CARBOXYHEMOGLOBIN;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARRHYTHMOGENESIS; ARTICLE; CALCIUM CURRENT; CELL MATURATION; CELL SIZE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; FEMALE; HEART ARRHYTHMIA; HEART DEVELOPMENT; HEART REPOLARIZATION; HEART VENTRICLE WALL; INFANT DISEASE; MALE; MATERNAL SMOKING; NEWBORN; NONHUMAN; PATCH CLAMP; POSTNATAL DEVELOPMENT; POTASSIUM CURRENT; PRENATAL EXPOSURE; PRIORITY JOURNAL; RAT; SMOKING; SUDDEN INFANT DEATH SYNDROME;

ACTION POTENTIALS; ANIMALS; ANIMALS, NEWBORN; ARRHYTHMIA; CALCIUM CHANNELS; CARBON MONOXIDE; CELL SIZE; CELLS, CULTURED; ELECTRIC CONDUCTIVITY; FEMALE; HEART; MATERNAL-FETAL EXCHANGE; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; PREGNANCY; RATS; RATS, WISTAR;

EID: 1642580523     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000109497.73223.4D     Document Type: Article

References (34)

1. Sullivan FM, Barlow SM. Review of risk factors for sudden infant death syndrome. Paediatr Perinat Epidemiol. 2001;15:144-200.
2. Aubard Y, Magne I. Carbon monoxide poisoning in pregnancy. BJOG. 2000;107:833-838.
3. Mereu G, Cammalleri M, Fa M, et al. Prenatal exposure to a low concentration of carbon monoxide disrupts hippocampal long-term potentiation in rat offspring. J Pharmacol Exp Ther. 2000;294:728-734.
4. Vaccari A, Ruiu S, Saba P, et al. Prenatal low-level exposure to CO alters postnatal development of hippocampal nitric oxide synthase and haem-oxygenase activities in rats. Int J Neuropsychopharmacol. 2001;4:219-222.
5. Browne CA, Colditz PB, Dunster KR. Infant autonomic function is altered by maternal smoking during pregnancy. Early Hum Dev. 2000;59:209-218.
6. Schwartz PJ, Stramba-Badiale M, Segantini A, et al. Prolongation of the QT interval and the sudden infant death syndrome. N Engl J Med. 1998;338:1709-1714.
7. Guntheroth WG, Spiers PS. Prolongation of the QT interval and the sudden infant death syndrome. N Engl J Med. 1998;339:1161.
8. Wren C. Cardiac causes for syncope or sudden death in childhood. Arch Dis Child. 1999;81:289-291.
9. Schwartz PJ, Priori SG, Dumaine R, et al. A molecular link between the sudden infant death syndrome and the long-QT syndrome. N Engl J Med. 2000;343:262-267.
10. Schwartz PJ, Priori SG, Bloise R, et al. Molecular diagnosis in a child with sudden infant death syndrome. Lancet. 2001;358:1342-1343.
11. Ackerman MJ, Siu BL, Sturner WQ, et al. Postmortem Molecular Analysis of SCN5A Defects in Sudden Infant Death Syndrome. JAMA. 2001;286:2264-2269.
12. Wedekind H, Smits JPP, Schulze-Bahr E, et al. De novo mutation in the SCN5A gene associated with early onset of sudden infant death. Circulation. 2001;104:1158-1164.
13. Schwartz PJ, Montemerlo M, Facchini M, et al. The QT interval throughout the first 6 months of life: a prospective study. Circulation. 1982;66:496-501.
14. Jeck CD, Boyden PA. Age-related appearance of outward currents may contribute to developmental differences in ventricular repolarization. Circ Res. 1992;71:1390-1403.
15. Guo W, Kamiya K, Toyama J. Modulated expression of transient outward current in cultured neonatal rat ventricular myocytes: comparison with development in situ. Cardiovasc Res. 1996;32:524-533.
16. Kilborn MJ, Fedida D. A study of the developmental changes in outward currents of rat ventricular myocytes. J Physiol (Lond) 1990;430:37-60.
17. Malfatto G, Rosen TS, Steinberg SF, et al. Sympathetic neural modulation of cardiac impulse initiation and repolarization in the newborn rat. Circ Res. 1990;66:427-437.
18. + channel isoforms in rat ventricle. J Physiol (Lond). 1997;500(pt 1):65-73.
19. f occurrence and properties in neonatal rat ventricular myocytes. Cardiovasc Res. 1999;42:416-423.
20. Cerbai E, Barbieri M, Li Q, et al. Ionic basis of action potential prolongation of hypertrophied cardiac myocytes isolated from hypertensive rats of different ages. Cardiovasc Res. 1994;28:1180-1187.
21. 2+ currents from newborn rat cardiomyocytes in primary culture. Pflugers Arch. 1994;428:241-249.
22. 2+ currents in ventricular myocytes from neonatal and adult rats. Can J Physiol Pharmacol. 1998;76:873-881.
23. + current in rat ventricular myocytes. Pflugers Arch. 1997;433:442-445.
24. + channel family in rat ventricular myocytes. Am J Physiol. 1997;272(4 pt 2):H1741-H1750.
25. Pandit SV, Clark RB, Giles WR, et al. A mathematical model of action potential heterogeneity in adult rat left ventricular myocytes. Biophys J. 2001;81:3029-3051.
26. Wibo M, Kilar F, Zheng L, et al. Influence of thyroid status on postnatal maturation of calcium channels, beta-adrenoceptors and cation transport ATPases in rat ventricular tissue. J Mol Cell Cardiol. 1995;27:1731-1743.
27. + currents in rat epicardial myocytes. Am J Physiol. 1998;274(3 pt 2):H915-H922.
28. Longo LD, Hill EP. Carbon monoxide uptake and elimination in fetal and maternal sheep. Am J Physiol. 1977;232:H324-H330.
29. Peyronnet J, Dalmaz Y, Ehrstrom M, et al. Long-lasting adverse effects of prenatal hypoxia on developing autonomic nervous system and cardiovascular parameters in rats. Pflugers Arch. 2002;443:858-865.
30. Hansson M, Kjorell U, Forsgren S. Ingrowth of sympathetic innervation occurs concomitantly with a decrease of ANP in the growing rat cardiac ventricles. Anat Embryol (Berl). 2001;203:35-44.
31. 2-regulated gene expression. FASEB J. 2002;16:1151-1162.
32. Kamiya K, Guo W, Yasui K, et al. Hypoxia inhibits the changes in action potentials and ion channels during primary culture of neonatal rat ventricular myocytes. J Mol Cell Cardiol. 1999;31:1591-1598.
33. Tomaselli G, Marban E. Electrophysiological remodeling in hypertrophy and heart failure. Cardiovasc Res. 1999;42:270-283.
34. Schwartz PJ, Priori SG, Napolitano C. Long QT syndrome. In: Zipes DP, Jalife J, eds. Cardiac Electrophysiology: From Cell to Bedside. 3rd ed. Philadelphia, Pa: WB Saunders Co; 2000:597-615.