Microencapsulation of a hydrophilic drug into a hydrophobic matrix using a salting-out procedure. I: Development and optimization of the process using factorial design

Journal of Microencapsulation

Volumn 21, Issue 2, 2004, Pages 125-135

  Mani, N ^a   Jun, H W ^b  

^a FOREST RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

Author keywords

Factorial design; Guaifenesin; Salting out; Sustained release; Wax microspheres

Indexed keywords

GUAIFENESIN; MICROSPHERE; POVIDONE; SODIUM CHLORIDE; SODIUM DIHYDROGEN PHOSPHATE; SORBITAN OLEATE; SORBITAN STEARATE; WATER; WAX; WETTING AGENT;

ARTICLE; CONTROLLED STUDY; DRUG SOLUBILITY; EMULSION; EXPERIMENTAL DESIGN; FACTORIAL ANALYSIS; HYDROPHILICITY; HYDROPHOBICITY; METHODOLOGY; MICROENCAPSULATION; PARTICLE SIZE; PHASE PARTITIONING; PROCESS OPTIMIZATION; SLOW DRUG RELEASE; SUSTAINED RELEASE FORMULATION;

DELAYED-ACTION PREPARATIONS; DRUG COMPOUNDING; EXPECTORANTS; FACTOR ANALYSIS, STATISTICAL; GUAIFENESIN; MICROSPHERES; PARTICLE SIZE; SALTS; SOLUBILITY; TIME FACTORS; WATER; WAXES;

EID: 1642569181     PISSN: 02652048     EISSN: None     Source Type: Journal    
DOI: 10.1080/02652040310001619776     Document Type: Article

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