P27 and Mib1 Expression in Actinic Keratosis, Bowen Disease, and Squamous Cell Carcinoma

American Journal of Dermatopathology

Volumn 26, Issue 1, 2004, Pages 22-26

  Oh, Chee Won ^a   Penneys, Neal ^b,c  

^a Gyeongsang National University School of Medicine   (South Korea)

^b Ameripath   (United States)

^c American Laboratory Associates   (United States)

Author keywords

Actinic keratosis; Bowen disease; Ki 67; P27; Squamous cell carcinoma

Indexed keywords

KI 67 ANTIGEN; PROTEIN P27;

ACTINIC KERATOSIS; ARTICLE; BOWEN DISEASE; CELL NUCLEUS; CELL PROLIFERATION; CELL TYPE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; EPIDERMIS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LABELING INDEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SQUAMOUS CELL CARCINOMA;

BOWEN'S DISEASE; CARCINOMA, SQUAMOUS CELL; CELL COUNT; CELL NUCLEUS; HUMANS; IMMUNOENZYME TECHNIQUES; KERATOSIS; KI-67 ANTIGEN; MICROFILAMENT PROTEINS; MUSCLE PROTEINS; PHOTOSENSITIVITY DISORDERS; SKIN NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 1642569161     PISSN: 01931091     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000372-200402000-00004     Document Type: Article

References (11)

1. Weedon D. Tumors of the epidermis. In: Weedon D, ed. Skin Pathology. New York, NY: Churchill Livingstone; 1998:642-654.
2. Jones RE Jr. Questions to the editorial board and other authorities. Am J Dermatopathol. 1984;6:301.
3. Polyak K, Lee MH, Erdjument-Bromage H, et al. Cloning of p27kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell. 1994;78:59-66.
4. Weidner N, Moore DH 2nd, Vartanian R. Correlation of Ki-67 antigen expression with mitotic figure index and tumor grade in breast carcinomas using the novel "Paraffin"-reactive MIB1 Antibody. Hum Pathol. 1994; 25:337-342.
5. Hu W, Cook T, Oh CW, et al. Expression of the cyclin-dependent kinase inhibitor p27 in keratoacanthoma. J Am Acad Dermatol. 2000;42:473-475.
6. Strayer DS, Santa Cruz DJ. Carcinoma in situ of the skin: a review of histopathology. J Cutan Pathol. 1980;7:244-259.
7. Ackerman AB, Guo Y, Vitale PA. Clue 25. In: Ackerman AB, Guo Y, Vitale PA, eds. Clues to Diagnosis in Dermatopathology. Chicago, Ill: ASCP; 1992:97-100.
8. Lu S, Tiekso J, Hietanen S, et al. Expression of cell-cycle proteins p53, p21 (WAF-1), PCNA, and Ki-67 in benign, premalignant and malignant skin lesions with implicated HPV involvement. Acta Derm Venereol. 1999;79:268-273.
9. Matsuta M, Kimura S, Kosegawa G, et al. Immunohistochemical detection of Ki-67 in epithelial skin tumors in formalin-fixed paraffin-embedded tissue sections using a new monoclonal antibody (MIB-1). J Dermatol. 1996;23:147-152.
10. McCluggage WG, Buhidma M, Tang L, et al. Monoclonal antibody MIB1 in the assessment of cervical squamous intraepithelial lesions. Int J Gynecol Pathol. 1996;15:131-136.
11. Piffko J, Bankfalvi A, Joos U, et al. Immunophenotypic analysis of normal mucosa and squamous cell carcinoma of the oral cavity. Cancer Detect Prev. 1999;23:45-56.