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Volumn 79, Issue 4, 1999, Pages 268-273

Expression of cell-cycle proteins p53, p21 (WAF-1), PCNA and Ki-67 in benign, premalignant and malignant skin lesions with implicated HPV involvement

Author keywords

Actinic keratosis; Cell cycle proteins; Extragenital Bowen's disease; Human papillomavirns; Keratoacanthoma; Squamous cell carcinoma; Verruca

Indexed keywords

CELL CYCLE PROTEIN; CYCLINE; KI 67 ANTIGEN; PROTEIN P21; PROTEIN P53; VIRUS DNA;

EID: 0032968189     PISSN: 00015555     EISSN: None     Source Type: Journal    
DOI: 10.1080/000155599750010634     Document Type: Article
Times cited : (44)

References (44)
  • 1
    • 0023145547 scopus 로고
    • The molecular genetics of cancers
    • 1. Bishop JM. The molecular genetics of cancers. Science 1987; 235: 305-311.
    • (1987) Science , vol.235 , pp. 305-311
    • Bishop, J.M.1
  • 2
    • 0027489384 scopus 로고
    • Clinical implications of the p53 tumor-suppressor gene
    • 2. Harris CC, Hollstein M. Clinical implications of the p53 tumor-suppressor gene. N Engl J Med 1993; 329: 1318-1327.
    • (1993) N Engl J Med , vol.329 , pp. 1318-1327
    • Harris, C.C.1    Hollstein, M.2
  • 3
    • 0028775245 scopus 로고
    • P21 inhibits cyclin shock
    • 3. Pines J. p21 inhibits cyclin shock. Nature 1994; 369: 520-521.
    • (1994) Nature , vol.369 , pp. 520-521
    • Pines, J.1
  • 4
    • 0018760324 scopus 로고
    • Characterization of a 54K dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells
    • 4. Linzer DI, Levine AJ. Characterization of a 54K dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells. Cell 1979; 17: 43-52.
    • (1979) Cell , vol.17 , pp. 43-52
    • Linzer, D.I.1    Levine, A.J.2
  • 5
    • 0027109075 scopus 로고
    • P53, guardian of the genome
    • 5. Lane DP. p53, guardian of the genome. Nature 1992; 358: 15-16.
    • (1992) Nature , vol.358 , pp. 15-16
    • Lane, D.P.1
  • 6
    • 0026669469 scopus 로고
    • P53 function and dysfunction
    • 6. Vogelstein B, Kinzler KW. p53 function and dysfunction. Cell 1992; 70: 523-526.
    • (1992) Cell , vol.70 , pp. 523-526
    • Vogelstein, B.1    Kinzler, K.W.2
  • 7
    • 0026794190 scopus 로고
    • Mutant p53 expression in solar keratosis: An immunohistochemical study
    • 7. Sim CS, Slater S, Mckee PH. Mutant p53 expression in solar keratosis: an immunohistochemical study. J Cutan Pathol 1992; 19: 302-308.
    • (1992) J Cutan Pathol , vol.19 , pp. 302-308
    • Sim, C.S.1    Slater, S.2    McKee, P.H.3
  • 9
    • 0027458942 scopus 로고
    • The p53 tumor suppressor gene as a common cellular target in human carcinogenesis
    • 9. Chang F, Syrjänen S, Kurvinen K, Syrjänen K. The p53 tumor suppressor gene as a common cellular target in human carcinogenesis. Am J Gastroenterol 1993; 88: 174-186.
    • (1993) Am J Gastroenterol , vol.88 , pp. 174-186
    • Chang, F.1    Syrjänen, S.2    Kurvinen, K.3    Syrjänen, K.4
  • 10
    • 0027359827 scopus 로고
    • WAF1, a potential mediator of p53 tumor suppression
    • 10. el-Diery WS, Tokino T, Velculescu VE. WAF1, a potential mediator of p53 tumor suppression. Cell 1993; 75: 817-825.
    • (1993) Cell , vol.75 , pp. 817-825
    • El-Diery, W.S.1    Tokino, T.2    Velculescu, V.E.3
  • 11
    • 0028220204 scopus 로고
    • P53-dependent inhibitin of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest
    • 11. Dulic V, Kaufmann WK, Wilson SJ. p53-dependent inhibitin of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. Cell 1994; 76: 1013-1023.
    • (1994) Cell , vol.76 , pp. 1013-1023
    • Dulic, V.1    Kaufmann, W.K.2    Wilson, S.J.3
  • 12
    • 0027496935 scopus 로고
    • The p21 cdk-interacting protein cip1 is a potent inhibitor of G1 cyclin-dependent kinases
    • 12. Harper JW, Adami GR, Wei N. The p21 cdk-interacting protein cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 1993; 75: 805-816.
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3
  • 13
    • 0028518750 scopus 로고
    • Cip1 blocks the initiation of DNA replication in xenopus extracts by inhibition of cyclin-dependent kenases
    • 13. Strausfeld UP, Howell M, Rempel R, Maller JL, Hunt T, Blow JJ. Cip1 blocks the initiation of DNA replication in xenopus extracts by inhibition of cyclin-dependent kenases. Curr Biol 1994; 4: 876-883.
    • (1994) Curr Biol , vol.4 , pp. 876-883
    • Strausfeld, U.P.1    Howell, M.2    Rempel, R.3    Maller, J.L.4    Hunt, T.5    Blow, J.J.6
  • 14
    • 0028352434 scopus 로고
    • The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA
    • 14. Waga S, Hannon GJ, Beach D, Stillman B. The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature 1994; 369: 574-578.
    • (1994) Nature , vol.369 , pp. 574-578
    • Waga, S.1    Hannon, G.J.2    Beach, D.3    Stillman, B.4
  • 16
    • 0027053240 scopus 로고
    • Proliferating cell nuclear antigen (PCNA) in common epidermal lesions
    • 16. Geary WA, Cooper PH. Proliferating cell nuclear antigen (PCNA) in common epidermal lesions. J Cutan Pathol 1992; 19: 458-468.
    • (1992) J Cutan Pathol , vol.19 , pp. 458-468
    • Geary, W.A.1    Cooper, P.H.2
  • 17
    • 0028298352 scopus 로고
    • Induction of proliferating cell nuclear antigen in differentiated keratinocytes of human papillomavirus-infected lesions
    • 17. Demeter LM, Stoler MH, Broker TR, Chow LT. Induction of proliferating cell nuclear antigen in differentiated keratinocytes of human papillomavirus-infected lesions. Human Pathol 1994; 25: 343-348.
    • (1994) Human Pathol , vol.25 , pp. 343-348
    • Demeter, L.M.1    Stoler, M.H.2    Broker, T.R.3    Chow, L.T.4
  • 18
    • 0023649972 scopus 로고
    • Cylin (PCNA, auxiliary protein of DNA polymerase delta) is a central component of the pathways leading to DNA replication and cell division
    • 18. Celis JE, Madsen P, Celis A. Cylin (PCNA, auxiliary protein of DNA polymerase delta) is a central component of the pathways leading to DNA replication and cell division. FEBS Let 1987; 220: 1-7.
    • (1987) FEBS Let , vol.220 , pp. 1-7
    • Celis, J.E.1    Madsen, P.2    Celis, A.3
  • 19
    • 0023091627 scopus 로고
    • Cylin/ PCNA is the auxiliary protein of DNA polymerase-delta
    • 19. Bravo R, Frank R, Blumdell PA, Macdonald-Bravo H. Cylin/ PCNA is the auxiliary protein of DNA polymerase-delta. Nature 1987; 326: 515-517.
    • (1987) Nature , vol.326 , pp. 515-517
    • Bravo, R.1    Frank, R.2    Blumdell, P.A.3    Macdonald-Bravo, H.4
  • 20
    • 0023618206 scopus 로고
    • Autoantibody to the proliferating cell nuclear antigen neutralizes the activity of the auxiliary protein for DNA polymerase delta
    • 20. Tan CK, Sullivan K, Li X, et al. Autoantibody to the proliferating cell nuclear antigen neutralizes the activity of the auxiliary protein for DNA polymerase delta. Nucleic Acid Res 1987; 15: 9299-9308.
    • (1987) Nucleic Acid Res , vol.15 , pp. 9299-9308
    • Tan, C.K.1    Sullivan, K.2    Li, X.3
  • 21
    • 0021212003 scopus 로고
    • Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67
    • 21. Gerdes J, Lemke H, Baisch H, Wacker HH, Schwab U, Stein H. Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67. J Immunol 1984; 133: 1710-1715.
    • (1984) J Immunol , vol.133 , pp. 1710-1715
    • Gerdes, J.1    Lemke, H.2    Baisch, H.3    Wacker, H.H.4    Schwab, U.5    Stein, H.6
  • 22
    • 0025810796 scopus 로고
    • Immunobiochemical and molecular biologic characterization of the cell proliferation-associated nuclear antigen that is defined by monoclonal antibody Ki-67
    • 22. Gerdes J, Li L, Schlueter C, et al. Immunobiochemical and molecular biologic characterization of the cell proliferation-associated nuclear antigen that is defined by monoclonal antibody Ki-67. Am J Pathol 1991; 138: 867-873.
    • (1991) Am J Pathol , vol.138 , pp. 867-873
    • Gerdes, J.1    Li, L.2    Schlueter, C.3
  • 23
    • 0002726457 scopus 로고
    • The application of immunohistochemistry in assessment of cellular proliferation
    • Hall PA, Levison DA, Wright NA, editors. Heidelberg; Springer-Verlag
    • 23. Yu CCW, Woods AL, Levison DA. The application of immunohistochemistry in assessment of cellular proliferation. In: Assessment of Cell Proliferation in Clinical Practice. Hall PA, Levison DA, Wright NA, editors. Heidelberg; Springer-Verlag, 1992: 141-159.
    • (1992) Assessment of Cell Proliferation in Clinical Practice , pp. 141-159
    • Yu, C.C.W.1    Woods, A.L.2    Levison, D.A.3
  • 24
    • 0025271203 scopus 로고
    • Association of human papillomavirus type 16 and 18 E6 protein with p53
    • 24. Werness BA, Levine AJ, Howley PM. Association of human papillomavirus type 16 and 18 E6 protein with p53. Science 1990; 248: 76-79.
    • (1990) Science , vol.248 , pp. 76-79
    • Werness, B.A.1    Levine, A.J.2    Howley, P.M.3
  • 25
    • 0024535228 scopus 로고
    • The human papillomavirus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product
    • 25. Dyson N, Howley PM, Munger K, Harlow E. The human papillomavirus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product. Science 1989; 243: 934-937.
    • (1989) Science , vol.243 , pp. 934-937
    • Dyson, N.1    Howley, P.M.2    Munger, K.3    Harlow, E.4
  • 26
    • 0026544710 scopus 로고
    • Squamous cell carcinoma of the skin (excluding lip and oral mucosa)
    • 26. Johnson TM, Rowe DE, Nelson BR, Swanson NA. Squamous cell carcinoma of the skin (excluding lip and oral mucosa). J Am Acad Dermatol 1992; 26: 467-484.
    • (1992) J Am Acad Dermatol , vol.26 , pp. 467-484
    • Johnson, T.M.1    Rowe, D.E.2    Nelson, B.R.3    Swanson, N.A.4
  • 27
    • 0029100067 scopus 로고
    • No evidence of human papillomavirus DNA in actinic keratosis
    • 27. Lu S, Syrjänen K, Havu VK, Syrjänen S. No evidence of human papillomavirus DNA in actinic keratosis. Arch Dermatol Res 1995; 287: 649-651.
    • (1995) Arch Dermatol Res , vol.287 , pp. 649-651
    • Lu, S.1    Syrjänen, K.2    Havu, V.K.3    Syrjänen, S.4
  • 28
    • 0029930528 scopus 로고    scopus 로고
    • Known HPV types have no association with keratoacanthomas
    • 28. Lu S, Syrjänen K, Havu VK, Syrjänen S. Known HPV types have no association with keratoacanthomas. Arch Dermatol Res 1996; 288: 129-132.
    • (1996) Arch Dermatol Res , vol.288 , pp. 129-132
    • Lu, S.1    Syrjänen, K.2    Havu, V.K.3    Syrjänen, S.4
  • 29
    • 0030449826 scopus 로고    scopus 로고
    • Expression of PCNA is associated with the presence of HPV DNA in skin warts
    • 29. Lu S, Syrjänen K, Havu VK, Syrjänen S. Expression of PCNA is associated with the presence of HPV DNA in skin warts. Arch Dermatol Res 1996; 289: 35-39.
    • (1996) Arch Dermatol Res , vol.289 , pp. 35-39
    • Lu, S.1    Syrjänen, K.2    Havu, V.K.3    Syrjänen, S.4
  • 30
    • 0030448511 scopus 로고    scopus 로고
    • Failure to demonstrate human papillomavirus (HPV) involvement in Bowen's disease of the skin
    • 30. Lu S, Syrjänen K, Havu VK, Syrjänen S. Failure to demonstrate human papillomavirus (HPV) involvement in Bowen's disease of the skin. Arch Dermatol Res 1996; 289: 40-45.
    • (1996) Arch Dermatol Res , vol.289 , pp. 40-45
    • Lu, S.1    Syrjänen, K.2    Havu, V.K.3    Syrjänen, S.4
  • 32
    • 0026012487 scopus 로고
    • A simple isolation of DNA from formalin-fixed, paraffin-embedded samples for PCR
    • 32. Kallio P, Syrjänen S, Tervahauta A, Syrjänen K. A simple isolation of DNA from formalin-fixed, paraffin-embedded samples for PCR. J Virol Methods 1991; 35: 39-47.
    • (1991) J Virol Methods , vol.35 , pp. 39-47
    • Kallio, P.1    Syrjänen, S.2    Tervahauta, A.3    Syrjänen, K.4
  • 33
    • 0027496935 scopus 로고
    • The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
    • 33. Harper JW, Adami GR, Wei N, Keyomarsi K, Elledge SJ. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 1993; 75: 805-816.
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 34
    • 0001622772 scopus 로고
    • A molecular portrait of human papillomavirus carcinogenesis
    • 34. Broker TR, Chow LT, Chin MT. A molecular portrait of human papillomavirus carcinogenesis. Cancer Cells 1989; 7: 197-208.
    • (1989) Cancer Cells , vol.7 , pp. 197-208
    • Broker, T.R.1    Chow, L.T.2    Chin, M.T.3
  • 35
    • 0025334305 scopus 로고
    • Infectious cycle of human papillomavirus type 11 in human foreskin xenografts in nude mice
    • 35. Stoler MH, Whitbeck A, Wolinsky SM, Broker TR, Chow LT, Howett MK. Infectious cycle of human papillomavirus type 11 in human foreskin xenografts in nude mice. J Virol 1990; 64: 3310-3318.
    • (1990) J Virol , vol.64 , pp. 3310-3318
    • Stoler, M.H.1    Whitbeck, A.2    Wolinsky, S.M.3    Broker, T.R.4    Chow, L.T.5    Howett, M.K.6
  • 36
    • 0024422238 scopus 로고
    • Differentiation-linked human papillomavirus type 6 and 11 transcription in genetal condylomata revealed by in situ hybridization with message-specific RNA probes
    • 36. Stoler MH, Wolinsky SM, Whilbeck A. Differentiation-linked human papillomavirus type 6 and 11 transcription in genetal condylomata revealed by in situ hybridization with message-specific RNA probes. Virology 1989; 172: 331-340.
    • (1989) Virology , vol.172 , pp. 331-340
    • Stoler, M.H.1    Wolinsky, S.M.2    Whilbeck, A.3
  • 37
    • 0025328320 scopus 로고
    • Sequential initiation of lagging and leading strand synthesis by two different polymerase complexes at the SV40 DNA replication origin
    • 37. Tsurimoto T, Melendy T, Stillman B. Sequential initiation of lagging and leading strand synthesis by two different polymerase complexes at the SV40 DNA replication origin. Nature 1990; 346: 534-539.
    • (1990) Nature , vol.346 , pp. 534-539
    • Tsurimoto, T.1    Melendy, T.2    Stillman, B.3
  • 38
    • 0028169236 scopus 로고
    • P21-containing cyclin kinases exist in both active and inactive states
    • 38. Zhang H, Hannon GJ, Beach. p21-containing cyclin kinases exist in both active and inactive states. Genes Dev 1994; 8: 1750-1758.
    • (1994) Genes Dev , vol.8 , pp. 1750-1758
    • Zhang, H.1    Hannon, G.J.2
  • 39
    • 0029058587 scopus 로고
    • Inhibition of cyclin-dependent kinases by p21
    • 39. Harper JW, Elledge SJ, Keyomarsi K, et al. Inhibition of cyclin-dependent kinases by p21. Mol Biol Cell 1995; 6: 387-400.
    • (1995) Mol Biol Cell , vol.6 , pp. 387-400
    • Harper, J.W.1    Elledge, S.J.2    Keyomarsi, K.3
  • 40
    • 0027724586 scopus 로고
    • PCNA independence of KI-67 expression in HPV infection
    • 40. Boon ME, Howard CV, van Velzen D. PCNA independence of KI-67 expression in HPV infection. Cel Biol Int 1993; 17: 1001-1004.
    • (1993) Cel Biol Int , vol.17 , pp. 1001-1004
    • Boon, M.E.1    Howard, C.V.2    Van Velzen, D.3
  • 42
    • 0025248598 scopus 로고
    • Activating mutations in p53 produce common conformational effect. A monoclonal antibody specific for the mutant form
    • 42. Gannon JV, Greaves R, Iggo R, Lane DP. Activating mutations in p53 produce common conformational effect. A monoclonal antibody specific for the mutant form. EMBO J 1990; 9: 1595-1602.
    • (1990) EMBO J , vol.9 , pp. 1595-1602
    • Gannon, J.V.1    Greaves, R.2    Iggo, R.3    Lane, D.P.4
  • 43
    • 0028832048 scopus 로고
    • P53 expression and cell proliferation in squamous cell carcinomas of the head and neck
    • 43. Nylander K, Stenling R, Gustafsson H, Zackrisson B, Roos G. p53 expression and cell proliferation in squamous cell carcinomas of the head and neck. Cancer 1994; 75: 87-93.
    • (1994) Cancer , vol.75 , pp. 87-93
    • Nylander, K.1    Stenling, R.2    Gustafsson, H.3    Zackrisson, B.4    Roos, G.5
  • 44
    • 0028212360 scopus 로고
    • Ki-67 and p53 expression in cutaneous Bowen's disease: An immunohistochemical study of fixed-embedded tissue sections
    • 44. Szekeres G, de Giacomoni P. Ki-67 and p53 expression in cutaneous Bowen's disease: an immunohistochemical study of fixed-embedded tissue sections. Acta Derm Venereol (Stockh) 1994; 74: 95-97.
    • (1994) Acta Derm Venereol (Stockh) , vol.74 , pp. 95-97
    • Szekeres, G.1    De Giacomoni, P.2


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