메뉴 건너뛰기




Volumn 47, Issue 1, 2004, Pages 15-22

Simulations of the cardiac action potential based on the Hodgkin-Huxley kinetics with the use of Microsoft Excel spreadsheets

Author keywords

Cardiac action potential; Excel; Mathematical model; Simulation

Indexed keywords

POTASSIUM ION; SODIUM ION; VOLTAGE GATED POTASSIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL;

EID: 1642567256     PISSN: 03044920     EISSN: 26660059     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (15)

References (27)
  • 1
    • 0017370379 scopus 로고
    • Reconstruction of the action potential of ventricular myocardial fibres
    • Beeler, G.W. and Reuter, H. Reconstruction of the action potential of ventricular myocardial fibres. J. Physiol. 268: 177-210, 1977.
    • (1977) J. Physiol. , vol.268 , pp. 177-210
    • Beeler, G.W.1    Reuter, H.2
  • 3
    • 0033082284 scopus 로고    scopus 로고
    • A methodology for simulating biological systems using Microsoft Excel
    • Brown, A.M. A methodology for simulating biological systems using Microsoft Excel. Comp. Methods Prog. Biomed. 58: 181-190, 1999.
    • (1999) Comp. Methods Prog. Biomed. , vol.58 , pp. 181-190
    • Brown, A.M.1
  • 4
    • 0023760886 scopus 로고
    • Studies of the sodium-calcium exchanger in bull-frog atrial myocytes
    • Campbell, D.L., Giles, W.R., Robinson, K. and Shibata, E.F. Studies of the sodium-calcium exchanger in bull-frog atrial myocytes. J. Physiol. 403: 317-340, 1988.
    • (1988) J. Physiol. , vol.403 , pp. 317-340
    • Campbell, D.L.1    Giles, W.R.2    Robinson, K.3    Shibata, E.F.4
  • 8
    • 0031571202 scopus 로고    scopus 로고
    • The NEURON simulation environment
    • Hines, M.L. and Carnevale, N.T. The NEURON simulation environment. Neural Comput. 9: 1179-1209, 1997.
    • (1997) Neural Comput. , vol.9 , pp. 1179-1209
    • Hines, M.L.1    Carnevale, N.T.2
  • 9
    • 35649001607 scopus 로고
    • A quantitative description of membrane current and its application to current pulse
    • Hodgkin, A.L. and Huxley, A.F. A quantitative description of membrane current and its application to current pulse. J. Physiol. 117: 500-544, 1952.
    • (1952) J. Physiol. , vol.117 , pp. 500-544
    • Hodgkin, A.L.1    Huxley, A.F.2
  • 10
    • 0027509511 scopus 로고
    • Cardiac pacemaking in the sinoatrial node
    • Irisawa, H. Brown, H.F. and Giles, W. Cardiac pacemaking in the sinoatrial node. Physiol. Rev. 73: 197-227, 1993.
    • (1993) Physiol. Rev. , vol.73 , pp. 197-227
    • Irisawa, H.1    Brown, H.F.2    Giles, W.3
  • 11
    • 0020422313 scopus 로고
    • Calcium currents of isolated bovine ventricular myocytes are fast and of large amplitude
    • Isenberg, G. and Klockner, U. Calcium currents of isolated bovine ventricular myocytes are fast and of large amplitude. Pflugers Arch. 395: 30-41, 1982.
    • (1982) Pflugers Arch. , vol.395 , pp. 30-41
    • Isenberg, G.1    Klockner, U.2
  • 12
    • 0027194486 scopus 로고
    • Ionic mechanisms of action potential prolongation at low temperatures in guinea-pig ventricular myocytes
    • Kiyosue, T., Arita, M., Muramatsu, H., Soindler, A.J. and Noble, D. Ionic mechanisms of action potential prolongation at low temperatures in guinea-pig ventricular myocytes. J. Physiol. 468: 85-106, 1993.
    • (1993) J. Physiol. , vol.468 , pp. 85-106
    • Kiyosue, T.1    Arita, M.2    Muramatsu, H.3    Soindler, A.J.4    Noble, D.5
  • 14
    • 0029913497 scopus 로고    scopus 로고
    • A model of the action potential and underlying membrane currents in a rabbit atrial cell
    • Lindblad, D.S., Murphey, C.R., Clark, J.W. and Giles, W.R. A model of the action potential and underlying membrane currents in a rabbit atrial cell. Am. J. Physiol. 271: H1666-H1696, 1996.
    • (1996) Am. J. Physiol. , vol.271
    • Lindblad, D.S.1    Murphey, C.R.2    Clark, J.W.3    Giles, W.R.4
  • 15
    • 0025891531 scopus 로고
    • A model of the ventricular cardiac action potential: Depolarization, repolarization and their interaction
    • Luo, C.H. and Rudy, Y. A model of the ventricular cardiac action potential: Depolarization, repolarization and their interaction. Circ. Res. 68: 1501-1526, 1991.
    • (1991) Circ. Res. , vol.68 , pp. 1501-1526
    • Luo, C.H.1    Rudy, Y.2
  • 16
    • 0028233422 scopus 로고
    • A dynamic model of the cardiac ventricular action potential. I. Simulations of ionic currents and concentration changes
    • Luo, C.H. and Rudy, Y. A dynamic model of the cardiac ventricular action potential. I. Simulations of ionic currents and concentration changes. Circ. Res. 74: 1071-1096, 1994.
    • (1994) Circ. Res. , vol.74 , pp. 1071-1096
    • Luo, C.H.1    Rudy, Y.2
  • 17
    • 0037191013 scopus 로고    scopus 로고
    • On the accuracy of statistical procedures in Microsoft Excel 2000 and Excel XP
    • McCullough, B.D. and Wilson, B. On the accuracy of statistical procedures in Microsoft Excel 2000 and Excel XP. Comput. Statist. Data Anal. 40: 713-721, 2002.
    • (2002) Comput. Statist. Data Anal. , vol.40 , pp. 713-721
    • McCullough, B.D.1    Wilson, B.2
  • 19
    • 0036901631 scopus 로고    scopus 로고
    • Modelling the heart: Insights, failure and progress
    • Noble, D. Modelling the heart: Insights, failure and progress. Bioessays 24: 1155-1163, 2002.
    • (2002) Bioessays , vol.24 , pp. 1155-1163
    • Noble, D.1
  • 20
    • 0034511516 scopus 로고    scopus 로고
    • Mathematical simulation of slowing of cardiac conduction velocity by elevated extracellular potassium
    • Nygren, A. and Giles, W.R. Mathematical simulation of slowing of cardiac conduction velocity by elevated extracellular potassium. Ann. Biomed. Eng. 28: 951-957, 2000.
    • (2000) Ann. Biomed. Eng. , vol.28 , pp. 951-957
    • Nygren, A.1    Giles, W.R.2
  • 21
    • 0009590174 scopus 로고
    • Neurosim for Windows
    • Revest, P. Neurosim for Windows. Trends Neurosci. 18: 556, 1995.
    • (1995) Trends Neurosci. , vol.18 , pp. 556
    • Revest, P.1
  • 22
    • 0023489831 scopus 로고
    • Passive properties and membrane currents of canine ventricular myocytes
    • Tseng, G.N., Robinson, R.B. and Hoffmann, B.F. Passive properties and membrane currents of canine ventricular myocytes. J. Gen. Physiol. 90: 671-701, 1987.
    • (1987) J. Gen. Physiol. , vol.90 , pp. 671-701
    • Tseng, G.N.1    Robinson, R.B.2    Hoffmann, B.F.3
  • 23
    • 0031908087 scopus 로고    scopus 로고
    • + channels by extracellular ATP and UTP in rat atrial myocytes
    • + channels by extracellular ATP and UTP in rat atrial myocytes. J. Cardiovasc. Pharmacol. 31: 203-211, 1998.
    • (1998) J. Cardiovasc. Pharmacol. , vol.31 , pp. 203-211
    • Wu, S.N.1    Liu, S.I.2    Hwang, T.L.3
  • 24
    • 0027371064 scopus 로고
    • Electrophysiologic properties of isolated adult cardiomyocytes from septic rats
    • Wu, S.N., Lue, S.I., Yang, S.L., Hsu, H.K. and Liu, M.S. Electrophysiologic properties of isolated adult cardiomyocytes from septic rats. Circ. Shock 41: 239-247, 1993.
    • (1993) Circ. Shock , vol.41 , pp. 239-247
    • Wu, S.N.1    Lue, S.I.2    Yang, S.L.3    Hsu, H.K.4    Liu, M.S.5
  • 25
    • 0028348651 scopus 로고
    • Molecular mechanism of cibenzoline-induced anticholinergic action in single atrial myocytes: Comparison with effect of disopyramide
    • Wu, S.N. Nakajima, T., Yamashita, T., Hamada, E., Hazama, H., Iwasawa, K., Omata, M. and Kurachi, Y. Molecular mechanism of cibenzoline-induced anticholinergic action in single atrial myocytes: comparison with effect of disopyramide. J. Cardiovasc.Pharmacol. 23: 618-623, 1994.
    • (1994) J. Cardiovasc. Pharmacol. , vol.23 , pp. 618-623
    • Wu, S.N.1    Nakajima, T.2    Yamashita, T.3    Hamada, E.4    Hazama, H.5    Iwasawa, K.6    Omata, M.7    Kurachi, Y.8
  • 26
    • 0019277122 scopus 로고
    • Reconstruction of sinoatrial node pacemaker potential based on the voltage clamp experiments
    • Yanagihara, K., Noma, A. and Irisawa, H. Reconstruction of sinoatrial node pacemaker potential based on the voltage clamp experiments. Jpn. J. Physiol. 30: 841-85, 1980.
    • (1980) Jpn. J. Physiol. , vol.30 , pp. 841-885
    • Yanagihara, K.1    Noma, A.2    Irisawa, H.3
  • 27
    • 0029024749 scopus 로고
    • + current in ventricular myocytes of the guinea pig type. Theoretical formulation and their role in repolarization
    • + current in ventricular myocytes of the guinea pig type. Theoretical formulation and their role in repolarization. Circ. Res. 77: 140-152, 1995.
    • (1995) Circ. Res. , vol.77 , pp. 140-152
    • Zeng, J.1    Laurita, K.R.2    Rosenbaum, D.S.3    Rudy, Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.