Decreased agglutinability of human erythrocytes by attachment of methoxy polyethylene glycol and the effect on erythrocyte oxygen-carrying ability

Clinical Hemorheology and Microcirculation

Volumn 29, Issue 3-4, 2003, Pages 401-407

  Ong, Karolyn ^a   Dimacali, Kristine ^a   Quintos, Ricardo ^a  

^a UNIVERSITY OF THE PHILIPPINES MANILA   (Philippines)

Author keywords

Agglutinability; Erythrocyte; Methoxy polyethylene glycol; Oxygen carrying ability

Indexed keywords

ETHYLENE GLYCOL DERIVATIVE; METHOXYPOLYETHYLENE GLYCOL; UNCLASSIFIED DRUG;

ANTIGENICITY; BLOOD TRANSFUSION; CELL MEMBRANE; CONFERENCE PAPER; CONTROLLED STUDY; COVALENT BOND; ERYTHROCYTE; HEMAGGLUTINATION; HUMAN; HUMAN CELL; OXYGEN AFFINITY; SPECTROPHOTOMETRY;

BLOOD TRANSFUSION; ERYTHROCYTE MEMBRANE; HEMAGGLUTINATION; HUMANS; OXYGEN; OXYHEMOGLOBINS; POLYETHYLENE GLYCOLS; RH ISOIMMUNIZATION; RH-HR BLOOD-GROUP SYSTEM;

EID: 1642562623     PISSN: 13860291     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (8)

1. J. Armstrong, H. Meiselman, R. Wenby and T. Fisher, Modulation of red blood cell aggregation and blood viscosity by the covalent attachment of pluronic copolymers, Biorheology 38 (2001), 239-47.
2. M. Stuart, Transfusion and transplantation immunology, 1999. Available: http://www.kcom.edu/faculty/chamberlain/ Website/MSTUART/Lect13.htm [Dec 4, 2001].
3. K. Murad, K. Mahany, C. Brugnara, F. Kuypers, J. Eaton and M. Scott, Structural and functional consequences of antigenic modulation of red blood cells with methoxypoly (ethylene glycol), Blood 93 (1999), 2121-2127.
4. J.H. Lee, J. Min and Y. Kim, Platelet adhesion onto segmented polyurethane film surfaces modified by addition and crosslinking of PEO-containing block copolymers, Biomaterials 21 (2000), 683-691.
5. M. Scott, A. Bradley and K. Murad, Camouflaged blood cells: Low-technology bioengineering for transfusion medicine?, Transfusion Medicine Reviews 14 (2000), 53-63.
6. G. Hortin, H.T. Lok and S. Huang, Progress toward preparation of universal donor red cells, Art. Cells, Blood Subs. Immob. Biotech. 25 (1997), 487-491.
7. M. Scott, K. Murad, F. Koumpuras, M. Talbot and J. Eaton, Chemical camouflage of antigenic determinants: stealth erythrocytes, Proc. Natl. Acad. Sci. 94 (1997), 7566-7571.
8. K. Armstrong, H. Meiselman and T. Fisher, Covalent binding of poly (ethylene glycol) (PEG) to the surface of red blood cells inhibits aggregation and reduces low shear blood viscosity, Am. J. Hematology 56 (1997), 26-28.