Synthesis, in vitro and in vivo 5-HT1A/5-HT2A serotonin receptor activity of new hybrid 1,2,3,4-tetrahydro-γ-carbolines with 1-(2-methoxyphenyl)piperazine moiety

Polish Journal of Pharmacology

Volumn 55, Issue 6, 2003, Pages 1013-1019

  Boksa, Jan ^a   Charakchieva Minol, Sijka ^a   Duszyńska, Beata ^a   Bugno, Ryszard ^a   Kłodzińska, Aleksandra ^a   Tatarczyńska, Ewa ^a   Chojnacka Wójcik, Ewa ^a   Bojarski, Andrzej J ^a  

^a INSTITUTE OF PHARMACOLOGY   (Poland)

Author keywords

1,2,3,4 tetrahydro carbolines; 2 methoxyphenylpiperazines; 5 HT1A ligands; 5 HT2A ligands

Indexed keywords

1,2,3,4 TETRAHYDRO GAMMA CARBOLINE DERIVATIVE; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 4 IODO 2,5 DIMETHOXYAMPHETAMINE; ACETIC ACID DERIVATIVE; CARBOLINE DERIVATIVE; KETANSERIN; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; PIPERAZINE DERIVATIVE; RADIOLIGAND; SEROTONIN 1A AGONIST; SEROTONIN 1A ANTAGONIST; SEROTONIN 1A RECEPTOR; SEROTONIN 2A ANTAGONIST; SEROTONIN 2A RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG CLASSIFICATION; DRUG DESIGN; DRUG INHIBITION; DRUG MEGADOSE; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HEAD TWITCH; HYBRID; IN VITRO STUDY; IN VIVO STUDY; LOWER LIP; MALE; MOUSE; NONHUMAN; RAT; RECEPTOR AFFINITY; SUBSTITUTION REACTION;

ANIMALS; BEHAVIOR, ANIMAL; BRAIN; CARBOLINES; MALE; MICE; PIPERAZINES; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTOR, SEROTONIN, 5-HT1A; RECEPTOR, SEROTONIN, 5-HT2A; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 1642543948     PISSN: 12306002     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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