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1642561192
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Alternatively, 8 could be obtained directly from the diol without purification of the sulfonate ester. Interestingly, some acetyl transfer to the 4′-OH (presumably originating from sulfur) was also observed in this case and 9 (7%) accompanied the formation of 8 (73%).
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22
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-
-
1642479525
-
-
note
-
Efforts to employ the anomeric thiolate of sialic acid as a nucleophile (see Scheme 1) to produce disaccharide 18 or trisaccharide 25 met with failure, only 2,3-elimination products were obtained.
-
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-
-
39
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1042288493
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44
-
-
1642438531
-
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note
-
This reaction has been observed for β-octyl, β-allyl, and β-8-methoxycarbonyloctyl galactosides and a variety of lactosides.
-
-
-
-
45
-
-
1642479524
-
-
note
-
13C NMR data, including TROESY spectra.
-
-
-
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