A theoretical model for simulating the outcome of mechanism based in vitro toxicity testing strategies

Toxicology in Vitro

Volumn 18, Issue 2, 2004, Pages 171-178

  Frazier, John M ^a  

^a AIR FORCE RESEARCH LABORATORY   (United States)

Author keywords

Biologically based modeling; Mechanistic toxicology; Test validation; Toxicity testing

Indexed keywords

ARTICLE; CYTOTOXICITY; EMPIRICISM; EXPERIMENT; IN VITRO STUDY; SIMULATION; THEORETICAL MODEL; TOXICITY TESTING; TOXICOKINETICS; VALIDATION PROCESS;

EID: 1642493710     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0887-2333(03)00144-9     Document Type: Article

References (2)

1. Frazier J.M. Predictive toxicodynamics. empirical/mechanistic approaches Toxicol. In Vitro. 11:1997;465-472.
2. Van Zutphen L.F.M., Balls M. Animal Alternatives, Welfare and Ethics. Proceedings of the 2nd World Congress on Alternatives and Animal Use in the Life Sciences. 1997;Elsevier, New York. p. 1260.