Synthesis of 3,7,8-15N3-N1-(β -D-erythropentofuranosyl)-5-guanidinohydantoin

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 46, Issue 14, 2003, Pages 1269-1277

  Yu, Hongbin ^a   Wishnok, John S ^a   Tannenbaum, Steven R ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

8 oxo 7,8 dihydro 2 deoxyguanosine; DNA damage; Guanidinohydantoin; Peroxynitrite; Stable isotope labeling

Indexed keywords

BIOMOLECULES; IRIDIUM COMPOUNDS; ISOTOPES; POTASSIUM COMPOUNDS; SODIUM COMPOUNDS;

8-OXO-7,8-DIHYDRO-2′-DEOXYGUANOSINE; CATALYTIC TRANSFER HYDROGENATION; CYCLOHEXENES; DNA DAMAGES; GUANIDINOHYDANTOIN; PEROXYNITRITES; STABLE-ISOTOPE LABELING; SYNTHESISED;

PURIFICATION;

3,7,8 N3,N1 (BETA DEXTRO ERYTHROPENTOFURANOSYL) 5 GUANIDINOHYDANTOIN; CYCLOHEXENE DERIVATIVE; DEOXYGUANOSINE DERIVATIVE; GUANIDINE DERIVATIVE; HYDANTOIN DERIVATIVE; IRIDIUM; NITROGEN 15; PALLADIUM; POTASSIUM DIHYDROGEN PHOSPHATE; SODIUM DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BROMINATION; CATALYSIS; ELECTROSPRAY MASS SPECTROMETRY; HYDROGENATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; OXIDATION; PH; PURIFICATION; SYNTHESIS;

EID: 1642487758     PISSN: 03624803     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlcr.789     Document Type: Article

References (20)

1. Moncada S, Palmer RMJ, Higgs EA. Pharm Rev 1991; 43: 109-142.
2. Leaf CD, Wishnok JS, Tannenbaum SR. Nitric Oxide From L-Arginine: A Bioregulatory System. Elsevier Science Publishers: New York, 1990.
3. Ischiropoulos H, Zhu L, Beckman JS. Biology of Nitric Oxide Part 2. Portland Press, Ltd: London, 1993.
4. Steenken S, Jovanovic SV. J Amer Chem Soc 1997; 119: 617-618.
5. Burney S, Niles JC, Dedon PC, Tannenbaum SR. Chem Res Toxicol 1999; 12: 513-520.
6. Douki T, Cadet J. Free Rad Res Comm 1996; 24: 369-380.
7. Kennedy LJ, Moore Jr K, Caulfield JL, Tannenbaum SR, Dedon PC. Chem Res Toxicol 1997; 10: 386-392.
8. Niles JC, Wishnok JS, Tannenbaum SR. Org Lett 2001; 3: 963-966.
9. Luo W, Muller JG, Rachlin EM, Burrows CJ. Chem Res Toxicol 2001; 14: 927-938.
10. Niles JC, Wishnok JS, Tannenbaum SR. J Amer Chem Soc 2001; 49: 12147-12151.
11. Uppu RM, Cueto R, Squadrito GL, Salgo MG, Pryor WA. Free Rad Biol Med 1996; 21: 407-411.
12. Burrows CJ, Muller JG, Kornyushyna O, Luo W, Duarte V, Leipold MD, David SS. Environ Health Perspect Suppl 2002; 110: 713-717.
13. Sugden KD, Campo CK, Martin BD. Chem Res Toxicol 2001; 14: 1315-1322.
14. Sugden KD, Martin BD. Environ Health Perspect Suppl 2002; 110: 725-728.
15. Joudah L, Moghaddas S, Bose RN. Chem Commun 2002; 742-1743.
16. Gu F, Stillwell WG, Wishnok JS, Shallop AJ, Jones RA, Tannenbaum SR. Biochem 2002; 41: 7508-7518.
17. Hermanns RCA, Zomer G, Jacquemijns M, Stavenuiter JFC, Westra JG, Teixeira AJR, van de Werken G. J Labell Compd Radiopharm 1994; XXXIV: 191-197.
18. Gannett PM, Sura TP. Synth Commun 1993; 23: 1611-1615.
19. Zhao H, Pagano AR, Wang W, Shallop A, Gaffney BL, Jones RA. J Org Chem 1997; 22: 7832-7835.
20. Abdel-Baky S, Giese RW. Synth Commun 1993; 23: 861-865.