Direct oxidation of guanine and 7,8-dihydro-8-oxoguanine in DNA by a high-valent chromium complex: A possible mechanism for chromate genotoxicity

Chemical Research in Toxicology

Volumn 14, Issue 9, 2001, Pages 1315-1322

  Sugden, K D ^a   Campo, C K ^a   Martin, B D ^a  

^a UNIVERSITY OF MONTANA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYGUANINE; CARCINOGEN; CHROMIUM DERIVATIVE; DNA; GUANINE; NUCLEIC ACID; OLIGONUCLEOTIDE; XENOBIOTIC AGENT;

ARTICLE; CARCINOGENICITY; CHEMICAL MODIFICATION; DNA DAMAGE; DNA STRAND; GENOTOXICITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MASS SPECTROMETRY; MOLECULAR INTERACTION; OXIDATION; REACTION ANALYSIS;

CARCINOGENS, ENVIRONMENTAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMIUM; DNA DAMAGE; GUANINE; HUMANS; MASS SPECTROMETRY; OXIDATION-REDUCTION; POINT MUTATION;

EID: 0034814369     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx010088+     Document Type: Article

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