Dietary L-carnitine increases plasma leptin concentrations of gestating sows fed one meal per day

Domestic Animal Endocrinology

Volumn 26, Issue 1, 2004, Pages 1-9

  Woodworth, J C ^a,b   Minton, J E ^a   Tokach, M D ^a   Nelssen, J L ^a   Goodband, R D ^a   Dritz, S S ^a   Koo, S I ^a,c   Owen, K Q ^a,b  

^a KANSAS STATE UNIVERSITY   (United States)

^b Lonza Inc USA   (United States)

^c UNIVERSITY OF CONNECTICUT   (United States)

Author keywords

Carnitine; Chromium; Leptin; Sow

Indexed keywords

EID: 1642485840     PISSN: 07397240     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.domaniend.2003.06.003     Document Type: Article

References (31)

1. Eder K., Ramanau A., Kluge H. Effect of L-carnitine supplementation on performance parameters in gilts and sows. J. Anim. Physiol. Anim. Nutr. (Berl.). 85:2001;73-80.
2. Musser R.E., Goodband R.D., Tokach M.D., Owen K.Q., Nelssen J.L., Blum S.A.et al. Effects of L-carnitine fed during gestation and lactation on sow and litter performance. J. Anim. Sci. 77:1999;3289-3295.
3. Campbell RG. The effects of chromium picolinate on fertility and fecundity of sows under commercial conditions. In: Proceedings of the 16th Annual Prince Feed Ingredient Conference. Quincy, IL, 1996.
4. Lindemann M.D., Wood C.M., Harper A.F., Kornegay E.T., Anderson R.A. Dietary chromium picolinate additions improve gain: feed and carcass characteristics in growing-finishing pigs and increase litter size in reproducing sows. J. Anim. Sci. 73:1995;457-465.
5. Real DE. Sow productivity, pig growth performance, and pork quality as influenced by micronutrients: carnitine, chromium, and niacin. MSc thesis, Kansas State University, 2001.
6. Montague C.T., Farooqi I.S., Whitehead J.P., Soos M.A., Rau H., Wareham N.J.et al. Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature. 387:1997;903-908.
7. Houseknecht K.L., Baile C.A., Matteri R.L., Spurlock M.E. The biology of leptin: a review. J. Anim. Sci. 76:1998;1405-1420.
8. Takken A., Williams K.C. A simplified procedure for long-term catheterisation of the anterior vena cava in adult pigs. Aust. Vet. J. 57:1981;17-20.
9. Estienne M.J., Harper A.F., Kozink D.M., Knight J.W. Serum and milk concentrations of leptin in gilts fed a high- or low-energy diet during gestation. Anim. Reprod. Sci. 75:2003;95-105.
10. Estienne M.J., Harper A.F., Barb C.R., Azain M.J. Concentrations of leptin in serum and milk collected from lactating sows differing in body condition. Domest. Anim. Endocrinol. 19:2000;275-280.
11. Mao J., Zak L.J., Cosgrove J.R., Shostak S., Foxcroft G.R. Reproductive, metabolic, and endocrine responses to feed restriction and GnRH treatment in primiparous, lactating sows. J. Anim. Sci. 77:1999;724-735.
12. Prunier A., Guadarrama C.A., Mourot J., Quesnel H. Influence of feed intake during pregnancy and lactation on fat body reserve mobilisation, plasma leptin and reproductive function of primiparous lactating sows. Reprod. Nutr. Dev. 41:2001;333-347.
13. Whisnant C.S., Harrell R.J. Effect of short-term feed restriction and refeeding on serum concentrations of leptin, luteinizing hormone and insulin in ovariectomized gilts. Domest. Anim. Endocrinol. 22:2002;73-80.
14. Woodworth JC. The effects of carnitine and/or chromium on blood hormones and metabolites of gestating swine. PhD dissertation, Kansas State University, 2002.
15. Hongu N., Sachan D.S. Caffeine, carnitine and choline supplementation of rats decreases body fat and serum leptin concentration as does exercise. J. Nutr. 130:2000;152-157.
16. Levin N., Nelson C., Gurney A., Vandlen R., de Sauvage F. Decreased food intake does not completely account for adiposity reduction after ob protein infusion. Proc. Natl. Acad. Sci. U.S.A. 93:1996;1726-1730.
17. Pelleymounter M.A., Cullen M.J., Baker M.B., Hecht R., Winters D., Boone T.et al. Effects of the obese gene product on body weight regulation in ob/ob mice. Science. 269:1995;540-543.
18. Masuzaki H., Ogawa Y., Sagawa N., Hosoda K., Matsumoto T., Mise H.et al. Nonadipose tissue production of leptin: leptin as a novel placenta-derived hormone in humans. Nat. Med. 3:1997;1029-1033.
19. Bado A., Levasseur S., Attoub S., Kermorgant S., Laigneau J.P., Bortoluzzi M.N.et al. The stomach is a source of leptin. Nature. 394:1998;790-793.
20. Wang J., Liu R., Hawkins M., Barzilai N., Rossetti L. A nutrient-sensing pathway regulates leptin gene expression in muscle and fat. Nature. 393:1998;684-688.
21. Caprio M., Fabbrini E., Isidori A.M., Aversa A., Fabbri A. Leptin in reproduction. Trends Endocrinol. Metab. 12:2001;65-72.
22. Karlsson C., Lindell K., Svensson E., Bergh C., Lind P., Billig H.et al. Expression of functional leptin receptors in the human ovary. J. Clin. Endocrinol. Metab. 82:1997;4144-4148.
23. Banks W.A., McLay R.N., Kastin A.J., Sarmiento U., Scully S. Passage of leptin across the blood-testis barrier. Am. J. Physiol. 276:1999;E1099-E1104.
24. Barash I.A., Cheung C.C., Weigle D.S., Ren H., Kabigting E.B., Kuijper J.L.et al. Leptin is a metabolic signal to the reproductive system. Endocrinology. 137:1996;3144-3147.
25. Armstrong J.D., Britt J.H. Nutritionally-induced anestrus in gilts: metabolic and endocrine changes associated with cessation and resumption of estrous cycles. J. Anim. Sci. 65:1987;508-523.
26. Vigersky R.A., Andersen A.E., Thompson R.H., Loriaux D.L. Hypothalamic dysfunction in secondary amenorrhea associated with simple weight loss. N. Engl. J. Med. 297:1977;1141-1145.
27. Berti L., Kellerer M., Capp E., Haring H.U. Leptin stimulates glucose transport and glycogen synthesis in C2C12 myotubes: evidence for a P13-kinase mediated effect. Diabetologia. 40:1997;606-609.
28. Muller G., Ertl J., Gerl M., Preibisch G. Leptin impairs metabolic actions of insulin in isolated rat adipocytes. J. Biol. Chem. 272:1997;10585-10593.
29. Kamohara S., Burcelin R., Halaas J.L., Friedman J.M., Charron M.J. Acute stimulation of glucose metabolism in mice by leptin treatment. Nature. 389:1997;374-377.
30. Wang J.L., Chinookoswong N., Scully S., Qi M., Shi Z.Q. Differential effects of leptin in regulation of tissue glucose utilization in vivo. Endocrinology. 140:1999;2117-2124.
31. Seck T., Englaro P., Blum W.F., Scheidt-Nave C., Rascher W., Ziegler R. et al. Leptin concentrations in serum from a randomly recruited sample of 50- to 80-year-old men and women: positive association with plasma insulin-like growth factors (IGFs) and IGF-binding protein-3 in lean, but not in obese individuals. Eur. J. Endocrinol. 138:1998;70-75.