IL-4 from Th2-type cells suppresses induction of delayed-type hypersensitivity elicited shortly after immunization

Immunology and Cell Biology

Volumn 81, Issue 6, 2003, Pages 424-430

  Jacysyn, Jacqueline F ^a   Abrahamsohn, Ises A ^a   Macedo, Mahasti S ^a,b  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b NONE   (Brazil)

Author keywords

Delayed type hypersensitivity; IL 4; Th2 cells

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; OVALBUMIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ANTIGEN SPECIFICITY; CELL TRANSFER; CONTROLLED STUDY; CYTOKINE PRODUCTION; DELAYED HYPERSENSITIVITY; FEMALE; FOOT PAD; IMMUNE RESPONSE; IMMUNITY; IMMUNIZATION; LYMPHOBLAST; MALE; MOUSE; NONHUMAN; PHENOTYPE; PROVOCATION TEST; RAT; RECIPIENT; REVIEW; T LYMPHOCYTE; TH2 CELL; TRYPANOSOMA CRUZI;

ANIMALS; ANTIBODIES, MONOCLONAL; CELLS, CULTURED; FEMALE; HYPERSENSITIVITY, DELAYED; IMMUNIZATION; INTERLEUKIN-10; INTERLEUKIN-4; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED DBA; OVALBUMIN; TH2 CELLS;

ANIMALIA; TRYPANOSOMA; TRYPANOSOMA CRUZI;

EID: 1642465408     PISSN: 08189641     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1711.2003.01194.x     Document Type: Review

References (35)

1. Pearce EJ, Caspar P, Grzych JM, Lewis FA, Sher A. Down-regulation of the Th1 cytokine production accompanies induction of Th2 response by a parasitic helminth, Schistosoma mansoni. J. Exp. Mod. 1991; 173: 159-66.
2. Curry AJ, Else KJ, Jones F, Bancroft A, Grencis RK, Dunne DW. Evidence that cytokine-mediated immune interaction induced by Schistosoma mansoni alter disease outcome in mice concurrently infected by Trichuris muris. J. Exp. Med. 1995; 181: 769-74.
3. Yan Y, Inuo G, Akao N, Tsukidate S, Fujita K. Down-regulation of murine susceptibility to cerebral malaria by inoculation with third-stage larvae of the filarial nematode Brugia pahangi. Parasitology 1997; 114: 333-8.
4. Kullberg MC, Pearce EJ, Hieny SE, Sher A, Berzofsky JA. Infection with Schistosoma mansoni alters Th1/Th2 cytokine response to a non-parasite antigen. J. Immunol. 1992; 148: 3264-70.
5. Pearlman E, Kazura J, Hazlett Jr FE, Boom WH. Modulation of murine cytokine responses to mycobacterial antigens by helminth-induced T helper 2 cell response. J. Immunol. 1993; 151: 4857-64.
6. Actor JK, Marshall MA, Eltoum IA, Buller RML, Berzofsky JA, Sher A. Increased susceptibility of mice infected with Schistosoma mansoni to recombinant vaccinia virus: association of viral persistence with egg granuloma formation. Eur. J. Immunol. 1994; 24: 3050-6.
7. Racke MK, Bonomo A, Scott DE et al. Cytokine-induced immune deviation as therapy for inflammatory autoimmune disease. J. Exp. Med. 1994; 180: 1961-6.
8. Biedermann T, Maillhammer R, Mai A et al. Reversal of established delayed type hypersensitivity reactions following therapy with IL-4 or antigen-specific Th2 cells. Eur. J. Immunol. 2001; 31: 1582-91.
9. Jacysyn JF, Abrahamsohn IA, Macedo MS. Modulation of delayed-type hypersensitivity during the time course of immune response to a protein antigen. Immunology 2001; 102: 373-9.
10. Alexander J, Curtis J. Development of delayed hypersensitivity responses in Mycobacterium lepraemurium infections in resistant and susceptible strains of mice. Immunology 1979; 36: 563-7.
11. Rizzo LV, Dekruyff RH, Umetsu DT, Caspi RR. Regulation of the interaction between Th1 and Th2 T cell clones to provide help for antibody production in vivo. Eur. J. Immunol. 1995; 25: 708-16.
12. Powrie F, Menon S, Coffman RL. Interleukin-4 and interleukin-10 synergize to inhibit cell-mediated immunity in vivo. Eur. J. Immunol. 1993; 23: 2223-9.
13. Mu H-H, Sewell WA. Regulation of DTH and IgE responses by IL-4 and IFN-γ in immunised mice given pertussis toxin. Immunology 1994; 83: 639-45.
14. Flores-Villanueva PO, Zheng XX, Strom TB, Stadecker MJ. Recombinant IL-10 and IL-10/Fc treatment down-regulate egg antigen-specific delayed hypersensitivity reactions and egg granuloma formation in schistosomiasis. J. Immunol. 1996; 156: 3315-20.
15. Li L, Elliott JF, Mosmann TR. IL-10 inhibits cytokine production, vascular leakage and swelling during T helper 1 cell-induced delayed-type hypersensitivity. J. Immunol. 1994; 153: 3967-78.
16. Curotto de Lafaille MA, Barbosa de Oliveira LC, Lima GC, Abrahamsohn IA. Trypanosoma cruzi: maintenance of parasite-specific T cell responses in lymph nodes during the acute phase of infection. Exp. Parasitol. 1990; 70: 164-74.
17. Ferreira AP, Faquim ES, Abrahamsohn IA, Macedo MS. Immunization with Ascaris suum extract impairs T cell functions in mice. Cell Immunol. 1995; 162: 202-10.
18. Zar JH. Biostatistical Analysis. New York: Prentice Hall 1984.
19. Mota I, Wong D. Homologous passive cutaneous anaphylactic activity of mouse antisera during the course of immunization. Life Sci. 1969; 8: 813-20.
20. Fox DA, Chiorazzi N, Katz DH. Hapten-specific IgE antibody response in mice. V. Differential resistance of IgE and IgG B lymphocytes to X-irradiation. J. Immunol. 1976; 117: 1622-8.
21. Ishizaka K, Adachi T. Generation of specific helper cells and suppressor cells in vitro for the IgE and IgG antibody response. J. Immunol. 1976; 117: 40-7.
22. Kurnick JT, Grönvik KO, Kimura AK. Long term growth in vitro of human T-cell blasts with maintenance of specificity and function. J. Immunol. 1979; 122: 1255-60.
23. Louis JA, Moedder E, MacDonald HR, Engers HD. Recognition of protozoan parasites by murine T lymphocytes. II. Role of the H-2 gene complex in interactions between antigen-presenting macrophages and Leishmania-immune T lymphocytes. J. Immunol. 1981; 126: 1661-6.
24. Parish CR, Liew FY. Immune response to chemically modified flagellin. III. Enhanced cell-mediated immunity during high and low zone tolerance to flagellin. J. Exp. Med. 1972; 135: 298-311.
25. Silver J, Benacerraf B. Dissociation of T cell helper function and delayed hypersensitivity. J. Immunol. 1974; 113: 1872-5.
26. + lymphocytes increase in vivo susceptibility to Trypanosoma cruzi infection. Cell Immunol. 1996; 170: 41-53.
27. Macedo MS, Faquim-Mauro E, Ferreira AP, Abrahamsohn IA. Immunomodulation induced by Ascaris suum extract in mice, effect of anti-interleukin-4 and anti-interleukin-10 antibodies. Scan. J. Immunol. 1998; 47: 10-18.
28. + T cells through IL-12 produced by Listeria-induced macrophages. Science 1993; 260: 547-9.
29. Ferguson TA, Dube P, Griffith TS. Regulation of contact hypersensitivity by interleukin 10. J. Exp. Med. 1994; 179: 1597-604.
30. Berg DJ, Leach MW, Kuhn R et al. Interleukin 10 but not interleukin 4 is a natural suppressant of cutaneous inflammatory responses. J. Exp. Med. 1995; 182: 99-108.
31. + T cells are important for the balance between protective and pathogenic cell-mediated immunity. J. Exp. Med. 1994; 179: 589-600.
32. Kitching AR, Tipping PG, Mutch DA, Huang XR, Holdsworth SR. Interleukin-4 deficiency enhances Th1 responses and crescentic glomerulonephritis in mice. Kidney Int. 1998; 53: 112-8.
33. Yoshino S, Murata Y, Ohsawa M. Successful induction of adjuvant arthritis in mice by treatment with a monoclonal antibody against IL-4. J. Immunol. 1998; 161: 6904-8.
34. Ward BJ, Griffin DE. Changes in cytokine production after measles virus vaccination: predominant production of IL-4 suggests induction of a Th2 response. Clin. Immunol. Immunopathol. 1993; 67: 171-7.
35. Mencacci A, Torosantucci A, Spaccapelo R, Romani L, Bistoni F, Cassone A. A mannoprotein constituent of Candida albicans that elicits different levels of delayed-type hypersensitivity, cytokine production, and anticandidal protection in mice. Infec. Immun 1994; 62: 5353-60.