Variability of glutathione during the menstrual cycle - Due to estrogen effects on hepatocytes?

Free Radical Biology and Medicine

Volumn 36, Issue 2, 2004, Pages 145-151

  Dabrosin, Charlotta ^a   Öllinger, Karin ^a  

^a LINKÖPING UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Breast; Free radicals; GSH; Hepatocytes; Liver; Microdialysis; Sex steroids

Indexed keywords

ESTRADIOL; ESTROGEN; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; PROGESTERONE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BREAST CELL; BREAST EPITHELIUM; CELL COMPOSITION; CELL CULTURE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EPITHELIUM CELL; ESTROGEN ACTIVITY; EXPOSURE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL; MALE; MENSTRUAL CYCLE; MICRODIALYSIS; NONHUMAN; NORMAL HUMAN; PERFUSION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT;

EID: 1642464751     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2003.10.028     Document Type: Article

References (48)

1. Hulka B.S., Stark A.T. Breast cancer: cause and prevention. Lancet. 346:1995;883-887.
2. Rossouw J.E., Anderson G.L., Prentice R.L., LaCroix A.Z., Kooperberg C., Stefanick M.L., Jackson R.D., Beresford S.A., Howard B.V., Johnson K.C., Kotchen J.M., Ockene J. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial. JAMA. 288:2002;321-333.
3. Cerutti P.A. Oxy-radicals and cancer. Lancet. 344:1994;862-863.
4. Cerutti P.A., Trump B.F. Inflammation and oxidative stress in carcinogenesis. Cancer Cells. 3:1991;1-7.
5. Pike M.C., Spicer D.V., Dahmoush L., Press M.F. Estrogens, progestogens, normal breast cell proliferation, and breast cancer risk. Epidemiol. Rev. 15:1993;17-35.
6. Shekhar M.P., Werdell J., Tait L. Interaction with endothelial cells is a prerequisite for branching ductal-alveolar morphogenesis and hyperplasia of preneoplastic human breast epithelial cells: regulation by estrogen. Cancer Res. 60:2000;439-449.
7. Liehr J.G. Genotoxic effects of estrogens. Mutat. Res. 238:1990;269-276.
8. Dabrosin C., Hammar M., Ollinger K. Impact of oestradiol and progesterone on antioxidant activity in normal human breast epithelial cells in culture. Free Radical Res. 28:1998;241-249.
9. Dabrosin C., Ollinger K., Ungerstedt U., Hammar M. Variability of glutathione levels in normal breast tissue and subcutaneous fat during the menstrual cycle: an in vivo study with microdialysis technique. J. Clin. Endocrinol. Metab. 82:1997;1382-1384.
10. Dickinson D.A., Forman H.J. Glutathione in defense and signaling: lessons from a small thiol. Ann.N.Y. Acad. Sci. 973:2002;488-504.
11. Cotgreave I.A., Gerdes R.G. Recent trends in glutathione biochemistry - glutathione-protein interactions: a molecular link between oxidative stress and cell proliferation? Biochem. Biophys. Res. Commun. 242:1998;1-9.
12. Filomeni G., Rotilio G., Ciriolo M.R. Cell signalling and the glutathione redox system. Biochem. Pharmacol. 64:2002;1057-1064.
13. Lu S.C. Regulation of hepatic glutathione synthesis: current concepts and controversies. FASEB J. 13:1999;1169-1183.
14. Halliwell B., Gutteridge J.M. The antioxidants of human extracellular fluids. Arch. Biochem. Biophys. 280:1990;1-8.
15. Meister A. Glutathione metabolism and its selective modification. J. Biol. Chem. 263:1988;17205-17208.
16. Perry R.R., Mazetta J.A., Levin M., Barranco S.C. Glutathione levels and variability in breast tumors and normal tissue. Cancer. 72:1993;783-787.
17. Chen G., Waxman D.J. Role of cellular glutathione and glutathione S-transferase in the expression of alkylating agent cytotoxicity in human breast cancer cells. Biochem. Pharmacol. 47:1994;1079-1087.
18. Bolinder J., Ungerstedt U., Arner P. Microdialysis measurement of the absolute glucose concentration in subcutaneous adipose tissue allowing glucose monitoring in diabetic patients. Diabetologia. 35:1992;1177-1180.
19. Pertoft H., Smedsrød B. Pretlow T.G., Pretlow T.B. In Cell Separation. Vol. 4:1987;1-24 Academic Press, New York.
20. Honegger C.G., Langemann H., Krenger W., Kempf A. Liquid chromatographic determination of common water-soluble antioxidants in biological samples. J. Chromatogr. 487:1989;463-468.
21. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:1951;265-275.
22. Ball P., Knuppen R. Catecholoestrogens (2- and 4-hydroxyoestrogens): chemistry, biogenesis, metabolism, occurrence and physiological significance. Acta Endocrinol. Suppl. (Copenhagen). 232:1980;1-127.
23. Cao K., Devanesan P.D., Ramanathan R., Gross M.L., Rogan E.G., Cavalieri E.L. Covalent binding of catechol estrogens to glutathione catalyzed by horseradish peroxidase, lactoperoxidase, or rat liver microsomes. Chem. Res. Toxicol. 11:1998;917-924.
24. Mizutani K., Ikeda K., Nishikata T., Yamori Y. Phytoestrogens attenuate oxidative DNA damage in vascular smooth muscle cells from stroke-prone spontaneously hypertensive rats. J. Hypertens. 18:2000;1833-1840.
25. Ruiz-Larrea M.B., Garrido M.J., Lacort M. Estradiol-induced effects on glutathione metabolism in rat hepatocytes. J. Biochem. (Tokyo). 113:1993;563-567.
26. Liehr J.G., Roy D. Free radical generation by redox cycling of estrogens. Free Radical Biol. Med. 8:1990;415-423.
27. Nutter L.M., Wu Y.Y., Ngo E.O., Sierra E.E., Gutierrez P.L., Abul-Hajj Y.J. An o-quinone form of estrogen produces free radicals in human breast cancer cells: correlation with DNA damage. Chem. Res. Toxicol. 7:1994;23-28.
28. Dwivedy I., Devanesan P., Cremonesi P., Rogan E., Cavalieri E. Synthesis and characterization of estrogen 2,3- and 3,4-quinones. Comparison of DNA adducts formed by the quinones versus horseradish peroxidase-activated catechol estrogens. Chem. Res. Toxicol. 5:1992;828-833.
29. Han X., Liehr J.G. Microsome-mediated 8-hydroxylation of guanine bases of DNA by steroid estrogens: correlation of DNA damage by free radicals with metabolic activation to quinones. Carcinogenesis. 16:1995;2571-2574.
30. Liehr J.G., Fang W.F., Sirbasku D.A., Ari-Ulubelen A. Carcinogenicity of catechol estrogens in Syrian hamsters. J. Steroid Biochem. 24:1986;353-356.
31. Devanesan P., Santen R.J., Bocchinfuso W.P., Korach K.S., Rogan E.G., Cavalieri E. Catechol estrogen metabolites and conjugates in mammary tumors and hyperplastic tissue from estrogen receptor-alpha knock-out (ERKO)/Wnt-1 mice: implications for initiation of mammary tumors. Carcinogenesis. 22:2001;1573-1576.
32. DeLeve L.D., Kaplowitz N. Importance and regulation of hepatic glutathione. Semin. Liver Dis. 10:1990;251-266.
33. Lu S.C., Garcia-Ruiz C., Kuhlenkamp J., Ookhtens M., Salas-Prato M., Kaplowitz N. Hormonal regulation of glutathione efflux. J. Biol. Chem. 265:1990;16088-16095.
34. Meister A. Biosynthesis and functions of glutathione, an essential biofactor. J. Nutr. Sci. Vitaminol. (Tokyo). 1992;. (Spec. No:1-6).
35. Igarashi T., Satoh T., Ono S., Iwashita K., Hosokawa M., Ueno K., Kitagawa H. Effect of steroidal sex hormones on the sex-related differences in the hepatic activities of gamma-glutamyltranspeptidase, glutathione S-transferase and glutathione peroxidase in rats. Res. Commun. Chem. Pathol. Pharmacol. 45:1984;225-232.
36. Hambali Z., Ngah W.Z., Wahid S.A., Kadir K.A. Effect of ovariectomy and sex hormone replacement on glutathione and glutathione-related enzymes in rat hepatocarcinogenesis. Pathology. 27:1995;30-35.
37. Gompel A., Malet C., Spritzer P., Lalardrie J.P., Kuttenn F., Mauvais-Jarvis P. Progestin effect on cell proliferation and 17 beta-hydroxysteroid dehydrogenase activity in normal human breast cells in culture. J. Clin. Endocrinol. Metab. 63:1986;1174-1180.
38. Anderson T.J., Ferguson D.J., Raab G.M. Cell turnover in the "resting" human breast: influence of parity, contraceptive pill, age and laterality. Br. J. Cancer. 46:1982;376-382.
39. Burdon R.H. Superoxide and hydrogen peroxide in relation to mammalian cell proliferation. Free Radic. Biol. Med. 18:1995;775-794.
40. Buttke T.M., Sandstrom P.A. Oxidative stress as a mediator of apoptosis. Immunol. Today. 15:1994;7-10.
41. Chiba T., Takahashi S., Sato N., Ishii S., Kikuchi K. Fas-mediated apoptosis is modulated by intracellular glutathione in human T cells. Eur. J. Immunol. 26:1996;1164-1169.
42. Voehringer D.W. BCL-2 and glutathione: alterations in cellular redox state that regulate apoptosis sensitivity. Free Radic. Biol. Med. 27:1999;945-950.
43. Thompson C.B. Apoptosis in the pathogenesis and treatment of disease. Science. 267:1995;1456-1462.
44. Cohen S.M., Purtilo D.T., Ellwein L.B. Ideas in pathology. Pivotal role of increased cell proliferation in human carcinogenesis. Mod. Pathol. 4:1991;371-382.
45. Siziopikou K.P., Prioleau J.E., Harris J.R., Schnitt S.J. Bcl-2 expression in the spectrum of preinvasive breast lesions. Cancer. 77:1996;499-506.
46. Sabourin J.C., Martin A., Baruch J., Truc J.B., Gompel A., Poitout P. Bcl-2 expression in normal breast tissue during the menstrual cycle. Int. J. Cancer. 59:1994;1-6.
47. Gompel A., Sabourin J.C., Martin A., Yaneva H., Audouin J., Decroix Y., Poitout P. Bcl-2 expression in normal endometrium during the menstrual cycle. Am. J. Pathol. 144:1994;1195-1202.
48. Kane D.J., Sarafian T.A., Anton R., Hahn H., Gralla E.B., Valentine J.S., Ord T., Bredesen D.E. Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species. Science. 262:1993;1274-1277.