Does granulosa cell apoptosis have a role in the etiology of unexplained infertility?

European Journal of Obstetrics and Gynecology and Reproductive Biology

Volumn 112, Issue 2, 2004, Pages 182-184

  Idil, Mehmet ^a   Çepni, Ismail ^a   Demirsoy, Gülten ^a   Öcal, Pelin ^a   Salihoǧlu, Funda ^a   Şenol, Hülya ^a   Elibol, Feyhan ^a   Irez, Tülay ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

Author keywords

Apoptosis; Granulosa cell; Unexplained infertility

Indexed keywords

DNA; GONADORELIN DERIVATIVE; GONADOTROPIN;

ADULT; APOPTOSIS; ARTICLE; ASPIRATION; CLINICAL ARTICLE; CONTROLLED STUDY; EMBRYO TRANSFER; FEMALE; FEMALE INFERTILITY; FERTILIZATION IN VITRO; FLOW CYTOMETRY; GRANULOSA CELL; HUMAN; HUMAN CELL; NICK END LABELING; OVARY FOLLICLE; OVULATION INDUCTION; PRIORITY JOURNAL; RANK SUM TEST; STATISTICS; STUDENT T TEST; UTERINE TUBE OCCLUSION;

EID: 1642463917     PISSN: 03012115     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-2115(03)00365-8     Document Type: Article

References (14)

1. Jones R.K., Searle R.F., Stewart S.A., Turner S., Bulmer J.N. Apoptosis, bcl-2 expression in normal human endometrium, endometriosis and adenomyosis. Hum. Reprod. 13:1998;3496-3502.
2. Jones R.K., Searle R.F., Stewart S.A., Turner S., Bulmer J.N. Apoptosis bcl-2 expression and proliferative activity of human endometrial stroma and endometrial granulated lymphocytes. Biol. Reprod. 58:1998;995-1002.
3. Tao J., Tilly K., Maravel D., Shifren J.L., Karajevsky S., Reed J.C. Differential expression of members of the bcl-2 gene family in proliferative and secretory human endometrium. J. Clin. Endocrinol. Metab. 82:1997;2738-2746.
4. Yuan W., Giudice L.C. Programmed cell death in human ovary is a function of follicle and corpus luteum status. J. Clin. Endocrinol. Metab. 82:1997;3148-3155.
5. Tilly J.L., Kowalski K.I., Johnson A.L., Hsueh A.J.W. Involvement of apoptosis in ovarian follicular atresia and postovulatory regression. Endocrinology. 5:1991;2799-2801.
6. Nakahara K., Saito H., Saito T.et al. The incidence of apoptotic bodies in membrana granulosa can predict prognosis of ova from patients participating in in vitro fertilization programs. Fertil. Steril. 68:1997;312-317.
7. Oosterhuis G.J.E., Michgelsen H.W., Lambalk C.B., Schoemaker J., Vermes I. Apoptotic cell death in human granulosa-lutein cells: a possible indicator of in vitro fertilization outcome. Fertil. Steril. 4:1998;747-749.
8. Nakahara K., Saito H., Saito T., Ito M., Ohta N., Hiroi M. Incidence of apoptotic bodies in membrana granulosa of the patients participating in an in vitro fertilization program. Fertil. Steril. 67:1997;302-308.
9. Billig H., Furuta I., Hsueh A.J. Gonadotropin releasing hormone directly induces apoptotic cell death in the rat ovary biochemical and in situ detection of deoxyribonucleic acid fragmentation in granulosa cells. Endocrinology. 134:1994;245-252.
10. Arnot A.M., Vandekerckhove P., DeBono M.A. Follicular volume and number during in vitro fertilization: association with oocyte developmental capacity and pregnancy rate. Hum. Reprod. 10:1995;256-261.
11. Spencer S.J., Cataldo N.A., Jaffe R.B. Apoptozis in the human female reproductive tract. Obstet. Gynecol. Survey. 5:1996;314-323.
12. Vermes I., Haanan C. Apoptosis and programmed cell death in health and disease. Adv. Clin. Chem. 31:1994;177.
13. Piquette G.N., Tilly J.L. Detection of apoptosis in human and rat ovarian follicles. J. Soc. Gynecol. Invest. 1:1994;297-301.
14. Investigation of the infertile couple. Birmingham, AL: The American Fertility Society; 1991. p. 33.