Cholesterol Metabolism in Rat Is Affected by Protocatechuic Acid

Journal of Nutritional Science and Vitaminology

Volumn 50, Issue 1, 2004, Pages 13-18

  Tamura, Akiko ^a   Fukushima, Michihiro ^a   Shimada, Ken Ichiro ^a   Han, Kyu Ho ^a   Sekikawa, Mitsuo ^a   Watanabe, Shoko ^a   Nakano, Masuo ^a   Matsumoto, Megumi ^b   Chiji, Hideyuki ^b  

^a OBIHIRO UNIVERSITY OF AGRICULTURE AND VETERINARY MEDICINE   (Japan)

^b FUJI WOMEN'S UNIVERSITY   (Japan)

Author keywords

HTGL mRNA; LCAT mRNA; LDL receptor mRNA; Protocatechuic acid; Serum cholesterol

Indexed keywords

APOLIPOPROTEIN B; APOLIPOPROTEIN E; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INTERMEDIATE DENSITY LIPOPROTEIN; LIVER TRIACYLGLYCEROL LIPASE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; PHOSPHATIDYLCHOLINE STEROL ACYLTRANSFERASE; PROTOCATECHUIC ACID; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL LIVER LEVEL; CHOLESTEROL METABOLISM; CONTROLLED STUDY; CORRELATION ANALYSIS; DIETARY INTAKE; FOOD COMPOSITION; FOOD INTAKE; GENE EXPRESSION; LIPID LIVER LEVEL; LIVER WEIGHT; LOW FAT DIET; MALE; NONHUMAN; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALIA;

EID: 1642462972     PISSN: 03014800     EISSN: 18817742     Source Type: Journal    
DOI: 10.3177/jnsv.50.13     Document Type: Article

References (28)

1. Mori H, Tanaka T, Sugie S, Yoshimi N, Kawamori T, Hirose Y, Ohnishi M. 1997. Chemoprevention by naturally occurring and synthetic agents in oral, liver, and large bowel carcinogenesis. J Cell Biochem Suppl 27: 35-41.
2. Kawamori T, Tanaka T, Kojima T, Suzui M, Ohnishi M, Mori H. 1994. Suppression of azoxymethane-induced rat colon aberrant crypt foci by dietary protocatechuic acid. Jpn J Cancer Res 85: 686-691.
3. Hirose Y, Tanaka T, Kawamori T, Ohnishi M, Makita H, Mori H, Satoh K, Hara A. 1995. Chemoprevention of urinary bladder carcinogenesis by the natural phenolic compound protocatechuic acid in rats. Carcinogenesis 16: 2337-2342.
4. Tseng TH, Tsheng YM, Lee YJ. 2001. Cytotoxicity effects of di- and tri-hydroxybenzaldehydes as a chemopreventive potential agent on tumor cells. Toxicology 161: 179-187.
5. Tseng TH, Wang CJ, Kao ES, Chu HY. 1996. Hibiscus protocatechuic acid protects against oxidative damage induced by t-butylhydroperoxide in rat primary hepatocytes. Chem Biol Interact 101: 137-148.
6. Tseng TH, Hsu JD, Lo MH, Chu HY, Chu FP, Huang CL, Wang CJ. 1998. Inhibitory effect of hibiscus protocatechuic acid on tumor promotion in mouse skin. Cancer Lett 126: 199-207.
7. Zhang Z, Chang Q, Huang Y, Walter KKH, Chen ZY. 2001. Characterization of antioxidants present in hawthorn fruits. J Nutr Biochem 12: 144-152.
8. Tsuda T, Horio F, Osawa T. 1999. Absorption and metabolism of cyanidin 3-O-β-D-glucoside in rats. FEBS Lett 449: 179-182.
9. Frank J, Kamal-Eldin A, Lundh T, Maatta K, Torronen R, Vessby B. 2002. Effects of dietary anthocyanins on tocopherols and lipids in rats. J Agric Food Chem 50: 7226-7230.
10. Preuss HG, Wallerstedt D, Talpur N, Tutuncuoglu SO, Echard B, Myers A, Bui M, Bagchi D. 2000. Effects of niacin-bound chromium and grape seed proanthocyanidin extract on the lipid profile of hypercholesterolemic subjects: a pilot study. J Med 31: 227-246.
11. American Institute of Nutrition. 1977. Report of the American Institute of Nutrition ad hoc committee on standards for nutritional studies. J Nutr 107: 1340-1348.
12. National Research Council. 1985. Guide for the Care and Use of Laboratory Animals. Publication no. 85-23 (rev.). National Institute of Health, Bethesda, MD.
13. Folch J, Lees M, Sloane-Stanley JH. 1957. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem 226: 497-509.
14. Matsubara Y, Sawabe A, Iizuka Y. 1990. Structures of new linoroid glycosides in lemon (Citrus limon Burm. f.) peelings. Agric Biol Chem 54: 1143-1148.
15. Grundy SM, Ahrens EH Jr, Miettinen TA. 1965. Quantitative isolation and gas-liquid chromatographic analysis of total fecal bile acids. J Lipid Res 6: 397-410.
16. Chomczynski P, Sacchi N. 1987. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159.
17. Liu CL, Wang JM, Chu CY, Cheng MT, Tseng TH. 2002. In vivo protective effect of protocatechuic acid on tertbutyl hydroperoxide-induced rat hepatotoxicity. Food Chem Toxicol 40: 635-641.
18. Igarashi K, Satoh M, Terahara N, Tsuda T, Tsushida T, Kajimoto O. 2000. Anthocyanin of biological function. In: Anthocyanins - Food Color with Health Benefits (Ohba R, Igarashi K, Tsukui A, eds). p 151-163, Kenpakusha Co. Ltd. Tokyo.
19. Matsumoto N, Okushio K, Hara Y. 1998. Effect of black tea polyphenols on plasma lipids in cholesterol-fed rats. J Nutr Sci Vitaminol 44: 337-342.
20. Sonoyama K, Nishikawa H, Kiriyama S, Niki R. 1995. Apolipoprotein mRNA in liver and intestine of rats is affected by dietary beet fiber or cholestyramine. J Nutr 125: 13-19.
21. Nimpf J, Schneider WJ. 2000. From cholesterol transport to signal transduction: low-density lipoprotein receptor, very low-density lipoprotein receptor, and apolipoprotein E receptor-2. Biochim Biophys Acta 1529: 287-298.
22. Goldstein JL, Kita T, Brown MS. 1983. Defective lipoprotein receptors and atherosclerosis. N Engl J Med 309: 288-296.
23. Brown MS, Kovanen PT, Goldstein JL. 1981. Regulation of plasma cholesterol by lipoprotein receptors. Science 212: 628-635.
24. Kita T, Brown MS, Bilheimer DW, Goldstein JL. 1982. Delayed clearance of very low-density and intermediate density lipoproteins with enhanced conversion to low-density lipoprotein in WHHL rabbits. Proc Natl Acad Sci USA 79: 5693-5697.
25. Olivecrona G, Olivecrona T. 1995. Triglyceride lipases and atherosclerosis. Curr Opin Lipidol 6: 291-305.
26. Medh DJ, Bowen SL, Fry GL, Ruben S, Hill J, Wong H, Chappell DA. 1999. Hepatic triglyceride lipase promotes low-density lipoprotein receptor-mediated catabolism of very low-density lipoproteins in vitro. J Lipid Res 40: 1263-1275.
27. Breckenridge WC, Little JA, Alaupovic P, Wang CS, Kuksis A, Kakis G, Lindgren F, Gardiner G. 1982. Lipoprotein abnormalities associated with a familial deficiency of hepatic lipase. Atherosclerosis 45: 161-179.
28. Pal S, Ho N, Santos C, Dubois P, Mamo J, Croft K, Allister E. 2003. Red wine polyphenolics increase LDL receptor expression and activity and suppress the secretion of Apo B 100 from human HepG2 cells. J Nutr 113: 700-706.