Biscoumarin: New class of urease inhibitors; Economical synthesis and activity

Bioorganic and Medicinal Chemistry

Volumn 12, Issue 8, 2004, Pages 1963-1968

  Khan, Khalid Mohammed ^a   Iqbal, Sajid ^a   Lodhi, Muhammad Arif ^a   Maharvi, Ghulam Murtaza ^a   Zia Ullah, ^a   Choudhary, Muhammad Iqbal ^a   Atta ur Rahman, ^a   Perveen, Shahnaz ^b  

^a UNIVERSITY OF KARACHI   (Pakistan)

^b PCSIR LABORATORIES COMPLEX   (Pakistan)

Author keywords

[No Author keywords available]

Indexed keywords

3,3' (12 PHENYLPROPYLIDENE)BIS(4 HYDROXYCOUMARIN); 3,3' (2 BROMOBENZYLIDENE)BIS(4 HYDROXYCOUMARIN); 3,3' (2 CHLOROBENZYLIDENE)BIS(4 HYDROXYCOUMARIN); 3,3' (2 METHOXYBENZYLIDENE)BIS(4 HYDROXYCOUMARIN); 3,3' (2 PYRIDYLMETHYLENE)BIS(4 HYDROXYCOUMARIN); 3,3' (2 PYRROLIDENE)BIS(4 HYDROXYCOUMARIN); 3,3' (3 CHLOROBENZYLIDENE)BIS(4 HYDROXYCOUMARIN); 3,3' (3 CINNAMYLIDENE)BIS(4 HYDROXYCOUMARIN); 3,3' (3 HYDROXYBENZYLIDENE)BIS(4 HYDROXYCOUMARIN); 3,3' (3 INDOLIDENE)BIS(4 HYDROXYCOUMARIN); 3,3' (3 METHOXYBENZYLIDENE)BIS(4 HYDROXYCOUMARIN); 3,3' (4 HYDROXYBENZYLIDENE)BIS(4 HYDROXYCOUMARIN); 3,3' (4 METHOXYBENZYLIDENE)BIS(4 HYDROXYCOUMARIN); 3,3' (4 NITROBENZYLIDENE)BIS(4 HYDROXYCOUMARIN); 3,3' (CROTONALIDINE)BIS(4 HYDROXYCOUMARIN); 3,3' (DIHYDROCINNAMYLIDENE)BIS(4 HYDROXYCOUMARIN); 3,3' ETHYLIDENEBIS(4 HYDROXYCOUMARIN); 3,3' N BUTYLIDENEBIS(4 HYDROXYCOUMARIN); 3,3' N HEXYLIDENEBIS(4 HYDROXYCOUMARIN); 3,3' N PENTYLIDENEBIS(4 HYDROXYCOUMARIN); DICOUMAROL; UNCLASSIFIED DRUG; UREASE INHIBITOR;

ARTICLE; DRUG ACTIVITY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTRON; ENZYME INHIBITION; SUBSTITUTION REACTION;

COUMARINS; ENZYME INHIBITORS; UREASE;

EID: 1642461633     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2004.01.010     Document Type: Article

References (20)

1. Mobley H.L.T., Island M.D., Hausinger R.P. Microbiol. Rev. 59:1995;451.
2. Mobley H.L.T., Island M.D., Hausinger R.P. Microbiol. Rev. 53:1989;85.
3. Khan K.M., Saify Z.S., Hayat S., Khan M.Z., Noor F., Choudhary M.I., Zia Ullah, Perveen S. J. Chem. Soc. Pak. 24:2002;226.
4. Khan K.M., Saify Z.S., Begum S., Noor F., Khan M.Z., Hayat S., Choudhary M.I., Perveen S., Zia Ullah Nat. Prod. Res. 17:2003;115.
5. Khan K.M., Saify Z.S., Zeeshan Khan A., Ahmed M., Saeed M., Abdel-Jalil R.J., Grubler G., Voelter W. Z. Naturforsch. 54b:1999;1210.
6. Khan K.M., Saify Z.S., Zeeshan Khan A., Ahmed M., Saeed M., Schick M., Kohlbau H.J., Voelter W. Arzneim-Forsch/Drug Res. 50:2000;915.
7. Saify Z.S., Khan K.M., Haider S.M., Zeeshan Shah S.T.A., Saeed M., Shekhani M.S., Voelter W.Z. Naturforsch. 54b:1999;1327.
8. Zaidi J.H., Naeem F., Iqbal R., Choudhary M.I., Khan K.M., Shah S.T.A., Hayat S., Voelter W. Z. Naturforsch. 56b:2001;689.
9. Khan K.M., Rahat S., Choudhary M.I., Atta-ur-Rahman Ghani U., Perveen S., Khatoon S., Dar A., Malik A. Helv. Chim. Acta. 85:2002;559.
10. Khan K. M.; Iqbal S.; Lodhi M. A.; Maharvi G. M.; Choudhary M. I.; Atta-ur-Rahman, Chohan Z. H.; Supuran, C. T. J. Enzym. Inhibition and Med. Chem. 2003, in press.
11. Link K.P. Fed. Proc. 4:1945;176.
12. Sengupta P., Sen M., Karuri P. J Ind. Chem. Soc. 62:1985;916.
13. Murray R.D.H. Fortschr Chem. Org. Naturst. 58:1991;83.
14. Abramovitch R.A., Gear J.R. Can. J. Chem. 36:1958;1501.
15. Wolff L. Ann. 315:1901;145.
16. Anschütz R., Wagner J., Junkersdorf P. Ann. 367:1909;217.
17. Singer L.A., Kong N.P. J. Am. Chem. Soc. 88:1966;5213.
18. Schonberg A., Ltif N. J. Am. Chem. Soc. 76:1954;6208.
19. Mitra A., Misra S.K., Petra A. Synth. Commun. 10:1980;915.
20. Weatherburn M.W. Anal. Chem. 39:1967;971.