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Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences

Volumn 54, Issue 10, 1999, Pages 1327-1336

Syntheses and evaluation of the analgesic activity of some 4-acetyl-4-phenylpiperidine and 4-hydroxy-4-phenylpiperidine derivatives

(8) Saify, Zafar Saeed a Khan, Khalid Mohammed b Haider, Syed Moazzam a Zeeshan, b Ali Shah, Syed Tasadaque b Saeed, Muhammad a Shekhani, Mohammed Saleh c Voelter, Wolfgang a

a UNIVERSITY OF TÜBINGEN (Germany)

b UNIVERSITY OF KARACHI (Pakistan)

c Ophidian Pharmaceuticals Inc (United States)

Author keywords

4 Acetyl 4 phenylpiperidine; 4 Hydroxy 4 phenylpiperidine; Analgesic activity

Indexed keywords

CHEMISTRY;

4-ACETYL-4-PHENYLPIPERIDINE; 4-HYDROXY-4-PHENYLPIPERIDINE; ANALGESIC ACTIVITY; BODY WEIGHT; PARENT COMPOUNDS; SPECTROSCOPIC TECHNIQUE; SYNTHESISED;

MAMMALS;

EID: 0040714077 PISSN: 09320776 EISSN: None Source Type: Journal
DOI: 10.1515/znb-1999-1017 Document Type: Article

Times cited : (19)

References (37)

1
- 0025769798
- P. L. Feldman, M. K. James, M. F. Brackeen, J. M. Bilotta, S. V. Schuster, A. P. Lahey. M. W. Lutz, M. R. Johnson, H. J. Leighton, J. Med. Chem. 34, 2202 (1991).
- (1991) J. Med. Chem. , vol.34 , pp. 2202
- Feldman, P.L.¹ James, M.K.² Brackeen, M.F.³ Bilotta, J.M.⁴ Schuster, S.V.⁵ Lahey, A.P.⁶ Lutz, M.W.⁷ Johnson, M.R.⁸ Leighton, H.J.⁹

2
- 0026535836
- D. I. C. Scopes, N. F. Hayes, D. E. Bays, D. Belton, J. Brain, D. S. Brown, D. B. Judd, A. B. McElroy, C. A. Meerholz, A. Naylor, A. G. Hyes, M. J. Sheehan, P. J. Birch, M. B. Tyres. J. Med. Chem. 35, 490 (1992).
- (1992) J. Med. Chem. , vol.35 , pp. 490
- Scopes, D.I.C.¹ Hayes, N.F.² Bays, D.E.³ Belton, D.⁴ Brain, J.⁵ Brown, D.S.⁶ Judd, D.B.⁷ McElroy, A.B.⁸ Meerholz, C.A.⁹ Naylor, A.¹⁰ Hyes, A.G.¹¹ Sheehan, M.J.¹² Birch, P.J.¹³ Tyres, M.B.¹⁴

3
- 0025141368
- M. J. Millan, Trends Pharmacol. Sci. 11, 70 (1990).
- (1990) Trends Pharmacol. Sci. , vol.11 , pp. 70
- Millan, M.J.¹

4
- 0027363635
- C. H. Mitch, J. D. Leander, L. G. Mendelsohn, W. N. Shaw, D. T. Wong, B. E. Cantrell, B. G. Johnson, J. K. Reel, J. D. Snoddy, A. E. Takemori, D. M. Zimmerman, J. Med. Chem. 36, 2842 (1993).
- (1993) J. Med. Chem. , vol.36 , pp. 2842
- Mitch, C.H.¹ Leander, J.D.² Mendelsohn, L.G.³ Shaw, W.N.⁴ Wong, D.T.⁵ Cantrell, B.E.⁶ Johnson, B.G.⁷ Reel, J.K.⁸ Snoddy, J.D.⁹ Takemori, A.E.¹⁰ Zimmerman, D.M.¹¹

5
- 0032542315
- a) J. B. Thomas, M. J. Fall, J. B. Cooper, R. B. Rothman, S. W. Mascarella, H. Xu, J. S. Partilla, C. M. Dersch, K. B. McCullough, B. E. Cantrell, D. M. Zimmerman, F. I. Carroll, J. Med. Chem. 41, 5188 (1998);
- (1998) J. Med. Chem. , vol.41 , pp. 5188
- Thomas, J.B.¹ Fall, M.J.² Cooper, J.B.³ Rothman, R.B.⁴ Mascarella, S.W.⁵ Xu, H.⁶ Partilla, J.S.⁷ Dersch, C.M.⁸ McCullough, K.B.⁹ Cantrell, B.E.¹⁰ Zimmerman, D.M.¹¹ Carroll, F.I.¹²

6
- 15444345625
- b) J. B. Thomas, S. W. Mascarella, R. B. Rothman, J. S. Partilla, H. Xu, K. B. McCullough, C. M. Dersch, B. E. Cantrell, D. M. Zimmerman, F. I. Carroll, J. Med. Chem. 41, 1980 (1998).
- (1998) J. Med. Chem. , vol.41 , pp. 1980
- Thomas, J.B.¹ Mascarella, S.W.² Rothman, R.B.³ Partilla, J.S.⁴ Xu, H.⁵ McCullough, K.B.⁶ Dersch, C.M.⁷ Cantrell, B.E.⁸ Zimmerman, D.M.⁹ Carroll, F.I.¹⁰

7
- 4243448437
- A. D. Brown, R. P. Dickinson, M. J. Wyeth, C. A. 120, 217271V (1994).
- (1994) C. A. , vol.120
- Brown, A.D.¹ Dickinson, R.P.² Wyeth, M.J.³

8
- 0030663835
- J. L. Castro, L. J. Street, A. R. Guiblin, R. A. Jelley, M. G. N. Russell, F. Sternfeld, M. S. Beer, J. A. Stanton, V. G. Matassa, J. Med. Chem. 40, 3497 (1997).
- (1997) J. Med. Chem. , vol.40 , pp. 3497
- Castro, J.L.¹ Street, L.J.² Guiblin, A.R.³ Jelley, R.A.⁴ Russell, M.G.N.⁵ Sternfeld, F.⁶ Beer, M.S.⁷ Stanton, J.A.⁸ Matassa, V.G.⁹

9
- 0028064950
- R. L. Hudkins, R. B. Mailman, D. L. DeHaven-Hudkins, J. Med. Chem. 37, 1964 (1994).
- (1994) J. Med. Chem. , vol.37 , pp. 1964
- Hudkins, R.L.¹ Mailman, R.B.² Dehaven-Hudkins, D.L.³

10
- 4243366244
- S. A. Frank, D. E. Prather, J. A. Ward, J. A. Werner, C. A. 123, 313767u (1995).
- (1995) C. A. , vol.123
- Frank, S.A.¹ Prather, D.E.² Ward, J.A.³ Werner, J.A.⁴

11
- 4243819860
- R. T. Lewis, A. M. Macleod, Chemical Abstracts 125, 33480j (1996).
- (1996) Chemical Abstracts , vol.125
- Lewis, R.T.¹ Macleod, A.M.²

12
- 15444342053
- G. I. Stevenson, I. Huscroft, A. M. MacLeod, C. J. Swain, M. A. Cascieri, G. G. Chicchi, M. I. Graham, T. Harrison, F. J. Kelleher, M. Kurtz, T. Ladduwahetty, K. J. Merchant, J. M. Metzger, D. E. MacIntyre, S. Sadowski, B. Sohal, A. P. Owens, J. Med. Chem. 41, 4623 (1998).
- (1998) J. Med. Chem. , vol.41 , pp. 4623
- Stevenson, G.I.¹ Huscroft, I.² Macleod, A.M.³ Swain, C.J.⁴ Cascieri, M.A.⁵ Chicchi, G.G.⁶ Graham, M.I.⁷ Harrison, T.⁸ Kelleher, F.J.⁹ Kurtz, M.¹⁰ Ladduwahetty, T.¹¹ Merchant, K.J.¹² Metzger, J.M.¹³ Macintyre, D.E.¹⁴ Sadowski, S.¹⁵ Sohal, B.¹⁶ Owens, A.P.¹⁷

13
- 4243366686
- H. Pruecher, G. Bartoszyk, C. A. 126, 251152r (1997).
- (1997) C. A. , vol.126
- Pruecher, H.¹ Bartoszyk, G.²

14
- 33947483170
- H. Kugita, T. Oine, H. Inoue, G. Hayashi, J. Med. Chem. 7, 313 (1965).
- (1965) J. Med. Chem. , vol.7 , pp. 313
- Kugita, H.¹ Oine, T.² Inoue, H.³ Hayashi, G.⁴

15
- 33947489339
- H. Kugita, H. Inoue, T. Oine, G. Hayashi, S. Nurimoto, J. Med. Chem. 7, 298 (1965).
- (1965) J. Med. Chem. , vol.7 , pp. 298
- Kugita, H.¹ Inoue, H.² Oine, T.³ Hayashi, G.⁴ Nurimoto, S.⁵

16
- 21844437339
- and references quoted therein
- P. D. Bailey, P. A. Millwood, P. D. Smith, J. Chem. Soc., Chem. Commun. 633 (1998) and references quoted therein.
- (1998) J. Chem. Soc., Chem. Commun. , pp. 633
- Bailey, P.D.¹ Millwood, P.A.² Smith, P.D.³

17
- 0029008372
- and references quoted therein
- X. Zheng, S. R. Salgia, W. B. Thompson, E. O. Dillingham, S. E. Bond, Z. Feng, K. R. Prasad, R. Gollamudi, J. Med. Chem. 38, 180 (1995) and references quoted therein.
- (1995) J. Med. Chem. 38 , vol.180
- Zheng, X.¹ Salgia, S.R.² Thompson, W.B.³ Dillingham, E.O.⁴ Bond, S.E.⁵ Feng, Z.⁶ Prasad, K.R.⁷ Gollamudi, R.⁸

18
- 0029165812
- F. Gabor, G. Hamilton, F. Pittner, J. Pharm. Sci. 84, 1120 (1995).
- (1120) J. Pharm. Sci. , vol.84 , pp. 1995
- Gabor, F.¹ Hamilton, G.² Pittner, F.³

19
- 0027381873
- S. Hosztafi, I. Köhegyi, C. Simon, Z. Fürst, Arzneim-Forsch./Drug Res. 43, 1200 (1993).
- (1993) Arzneim-Forsch./Drug Res. , vol.43 , pp. 1200
- Hosztafi, S.¹ Köhegyi, I.² Simon, C.³ Fürst, Z.⁴

20
- 0026029548
- K. Prokai-Tatrai, E. Pop, W. Anderson, J-L. Lin, M. E. Brewster, N. Bodor, J. Pharm. Sci. 80, 255 (1991).
- (1991) J. Pharm. Sci. , vol.80 , pp. 255
- Prokai-Tatrai, K.¹ Pop, E.² Anderson, W.³ Lin, J.-L.⁴ Brewster, M.E.⁵ Bodor, N.⁶

21
- 0027420561
- M. Winn, B. De, T. M. Zydowsky, R. J. Altenbach, F. Z. Basha, S. A. Boyd, M. E. Brune, S. A. Buckner, D. Crowell, I. Drizin, A. A. Hancock, H-S. Jae, J. A. Kester, J. Y. Lee, R. A. Mantei, K. C. Marsh, E. I. Novosad, K. W. Oheeim, S. H. Rosenberg, K. Shiosaki, B. K. Sorensen, K. Spina, G. M. Sullivan, A. S. Tasker, T. W. Geldern, R. B. Warner, T. J. Opgenorth, D. J. Kerkman, J. F. DeBernardis, J. Med. Chem. 36, 2676 (1993).
- (1993) J. Med. Chem. , vol.36 , pp. 2676
- Winn, M.¹ De, B.² Zydowsky, T.M.³ Altenbach, R.J.⁴ Basha, F.Z.⁵ Boyd, S.A.⁶ Brune, M.E.⁷ Buckner, S.A.⁸ Crowell, D.⁹ Drizin, I.¹⁰ Hancock, A.A.¹¹ Jae, H.-S.¹² Kester, J.A.¹³ Lee, J.Y.¹⁴ Mantei, R.A.¹⁵ Marsh, K.C.¹⁶ Novosad, E.I.¹⁷ Oheeim, K.W.¹⁸ Rosenberg, S.H.¹⁹ Shiosaki, K.²⁰ more..

22
- 0032482486
- M. A. Lago, T. T. Nguyen, P. Bhatnagar, Tetrahedron Lett. 39, 3885 (1998).
- (1998) Tetrahedron Lett. , vol.39 , pp. 3885
- Lago, M.A.¹ Nguyen, T.T.² Bhatnagar, P.³

23
- 0000804976
- A. Wang, E. R. Biehl, Heterocycles 45, 1929 (1997).
- (1997) Heterocycles , vol.45 , pp. 1929
- Wang, A.¹ Biehl, E.R.²

24
- 0031372476
- M. Vlassa, J. Barbe, P. Brounat, P. Indian J. Heterocycl. Chem. 7, 149 (1997).
- (1997) J. Heterocycl. Chem. , vol.7 , pp. 149
- Vlassa, M.¹ Barbe, J.² Brounat, P.³ Indian, P.⁴

25
- 0029767854
- B. Jordaan, D. W. Oliver, I. C. Dormehl, N. Hugo, Arzneim-Forsch./Drug Res. 46, 844 (1996).
- (1996) Arzneim-Forsch./Drug Res. , vol.46 , pp. 844
- Jordaan, B.¹ Oliver, D.W.² Dormehl, I.C.³ Hugo, N.⁴

26
- 0008858685
- D. M. Aronov, Kardiologiya 36, 92 (1996).
- (1996) Kardiologiya , vol.36 , pp. 92
- Aronov, D.M.¹

27
- 0031944612
- S. Fetzner, Appl. Microbiol. Biotechnol. 49, 237 (1998).
- (1998) Appl. Microbiol. Biotechnol. , vol.49 , pp. 237
- Fetzner, S.¹

28
- 0020988594
- W. Hotz, Adv. Lipid Res. 20, 195 (1983).
- (1983) Adv. Lipid Res. , vol.20 , pp. 195
- Hotz, W.¹

29
- 0027168937
- G. Franceschini, R. Paoletti, Cardiovasc. Drug Ther. 7, 297 (1993).
- (1993) Cardiovasc. Drug Ther. , vol.7 , pp. 297
- Franceschini, G.¹ Paoletti, R.²

30
- 0003799353
- M. E. Wolf (ed): Therapeutic Agents, John Wiley and Sons, New York
- J. V. Aldrich, in M. E. Wolf (ed): Burger's Medicinal Chemistry and Drug Discovery Vol. 3 (Therapeutic Agents), John Wiley and Sons, New York (1996).
- (1996) Burger's Medicinal Chemistry and Drug Discovery , vol.3
- Aldrich, J.V.¹

31
- 0020663764
- S. J. Paterson, L. E. Robson, H. W. Kostertitz, Br. Med. Bull. 39, 31 (1983).
- (1983) Br. Med. Bull. , vol.39 , pp. 31
- Paterson, S.J.¹ Robson, L.E.² Kostertitz, H.W.³

32
- 0013800287
- P. S. Portoghese, J. Med. Chem. 8, 609 (1965).
- (1965) J. Med. Chem. , vol.8 , pp. 609
- Portoghese, P.S.¹

33
- 0040022800
- Stockholm, Pergamon Press, and references quoted therein
- D. E. Koshland, Jr. in Proceedings of the First International Pharmacological Meeting, Stockholm, Pergamon Press, Vol.7, (1963) pp.161, and references quoted therein.
- (1963) Proceedings of the First International Pharmacological Meeting , vol.7 , pp. 161
- Koshland D.E., Jr.¹

34
- 33846910647
- P. A. J. Janssen, N. B. Eddy, J. Med. Chem. 2, 31 (1960).
- (1960) J. Med. Chem. , vol.2 , pp. 31
- Janssen, P.A.J.¹ Eddy, N.B.²

35
- 0015945748
- B. Carnmalm, E. Jacupovic, L. Johannsson, T. de Paulis, S. Ramsby, N. E. Stjernstrom, A. L. Renyi, S. B. Ross, S. O. Ogren, J. Med. Chem. 17, 65 (1974).
- (1974) J. Med. Chem. , vol.17 , pp. 65
- Carnmalm, B.¹ Jacupovic, E.² Johannsson, L.³ De Paulis, T.⁴ Ramsby, S.⁵ Stjernstrom, N.E.⁶ Renyi, A.L.⁷ Ross, S.B.⁸ Ogren, S.O.⁹

36
- 0016786454
- C. J. Niemegeers, J. A. Van-Bruggen, P. A. Janssen, Arzneim-Forsch./Drug Res. 25, 1505 (1975).
- (1975) Arzneim-Forsch./Drug Res. , vol.25 , pp. 1505
- Niemegeers, C.J.¹ Van-Bruggen, J.A.² Janssen, P.A.³

37
- 0024269972
- L. C. di-Stasi, M. Costa, S. L. Mendacolli, M. Kirizawa, C. Gomes, G. Trolin, J. Ethnopharmacol. 24, 205 (1988).
- (1988) J. Ethnopharmacol. , vol.24 , pp. 205
- Di-Stasi, L.C.¹ Costa, M.² Mendacolli, S.L.³ Kirizawa, M.⁴ Gomes, C.⁵ Trolin, G.⁶

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