Multiple Pharmacophores for the Investigation of Human UDP-Glucuronosyltransferase Isoform Substrate Selectivity

Molecular Pharmacology

Volumn 65, Issue 2, 2004, Pages 301-308

  Sorich, Michael J ^a   Miners, John O ^b,c   McKinnon, Ross A ^a   Smith, Paul A ^b  

^a UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^b FLINDERS UNIVERSITY   (Australia)

^c FLINDERS MEDICAL CENTRE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCURONOSYLTRANSFERASE; ISOENZYME; UDP GLUCURONOSYLTRANSFERASE, UGT1A6; UDP GLUCURONOSYLTRANSFERASE, UGT1A7; UDP GLUCURONSYLTRANSFERASE 1A9; UDP-GLUCURONOSYLTRANSFERASE, UGT1A6; UDP-GLUCURONOSYLTRANSFERASE, UGT1A7; UDP-GLUCURONSYLTRANSFERASE 1A9; UGT2B11 PROTEIN; UNCLASSIFIED DRUG; URIDINE 5' DIPHOSPHOGLUCURONOSYLTRANSFERASE 1A6; URIDINE 5' DIPHOSPHOGLUCURONOSYLTRANSFERASE 1A7; URIDINE 5' DIPHOSPHOGLUCURONOSYLTRANSFERASE 1A9; URIDINE 5' DIPHOSPHOGLUCURONOSYLTRANSFERASE 2B4; XENOBIOTIC AGENT;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DNA FINGERPRINTING; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME SPECIFICITY; GLUCURONIDATION; HUMAN; HYDROGEN BOND; METABOLISM; MOLECULAR MODEL; PATTERN RECOGNITION; PHARMACOPHORE; PHYSIOLOGY; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

GLUCURONOSYLTRANSFERASE; HUMANS; ISOENZYMES; MODELS, MOLECULAR; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 1642457197     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.65.2.301     Document Type: Article

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