Effect of novel benzoylphenylurea derivatives on DNA polymerase α activity using the synthesome-based in vitro model system

Investigational New Drugs

Volumn 21, Issue 4, 2003, Pages 421-428

  Abdel Aziz, Waleed ^a   Hickey, Robert ^a   Edelman, Martin ^b   Malkas, Linda ^a,c  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MARYLAND GREENEBAUM CANCER CENTER   (United States)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

BPU derivatives; DNA polymerase ; DNA replication; DNA synthesome; Tubulin

Indexed keywords

ANTINEOPLASTIC AGENT; BACTERIAL ENZYME; BENZOYLPHENYLUREA; CARBANILAMIDE DERIVATIVE; DNA DIRECTED DNA POLYMERASE ALPHA; DNA DIRECTED DNA POLYMERASE BETA; NSC 624548; NSC 639828; NSC 639829; NSC 654259; UNCLASSIFIED DRUG;

ARTICLE; CATTLE; CONTROLLED STUDY; DRUG EFFECT; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PURIFICATION; ESCHERICHIA COLI; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; THYMUS;

ANIMALS; CATTLE; CELL LINE, TUMOR; DNA POLYMERASE I; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HUMANS; PHENYLUREA COMPOUNDS;

EID: 1642452916     PISSN: 01676997     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1026247101229     Document Type: Article

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