MG-63 human osteosarcoma cells grown in monolayer and as three-dimensional tumor spheroids present a different metabolic profile: A 1H NMR study

FEBS Letters

Volumn 557, Issue 1-3, 2004, Pages 148-154

  Santini, Maria Teresa ^a,b   Rainaldi, Gabriella ^a,b   Romano, Rocco ^b,c   Ferrante, Antonella ^a   Clemente, Stefania ^c   Motta, Andrea ^b,d   Indovina, Pietro Luigi ^b,c  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b INFM   (Italy)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^d CNR Consiglio Nazionale delle Ricerche   (Italy)

Author keywords

High resolution nuclear magnetic resonance spectroscopy; Human osteosarcoma cell; Monolayer culture; Three dimensional tumor spheroid

Indexed keywords

ALANINE; LACTIC ACID;

ARTICLE; CELL CYCLE; CONTROLLED STUDY; ENERGY METABOLISM; HUMAN; HUMAN CELL; HYPOXIA; LIPID METABOLISM; MONOLAYER CULTURE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; TUMOR SPHEROID;

EID: 1642450627     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(03)01466-2     Document Type: Article

References (38)

1. Sutherland R.M. Science. 240:1988;177-184.
2. Durand R.E. Cell Tissue Kinet. 23:1990;141-159.
3. Santini M.T., Rainaldi G., Indovina P.L. Crit. Rev. Oncol. Hematol. 36:2000;75-87.
4. Barba I., Cabanas M.E., Arus C. Cancer Res. 59:1999;1861-1868.
5. Le Moyec L., Tatoud R., Eugene M., Gauville C., Primot I., Charlemagne D., Calvo F. Br. J. Cancer. 66:1992;623-628.
6. Cooper W.A., Bartier W.A., Rideout D.C., Delikatny E.J. Magn. Reson. Med. 45:2001;1001-1010.
7. Santini M.T., Romano R., Rainaldi G., Filippini P., Bravo E., Porcu L., Motta A., Calcabrini A., Meschini S., Indovina P.L., Arancia G. Biochim. Biophys. Acta. 1531:2001;111-131.
8. Wehrle J.P., Ng C.E., McGovern K.A., Aiken N.R., Shungu D.C., Change E.M., Glickson J.D. NMR Biomed. 13:2000;349-360.
9. Chen T.B., Huzak M., Macura S., Vuk-Pavlovic S. Cancer Lett. 86:1994;41-51.
10. Sillerud L.O., Freyer J.P., Neeman M., Mattingly M.A. Magn. Reson. Med. 16:1990;380-389.
11. Bär P.R. Life Sci. 59:1996;369-378.
12. Oberhammer F.A., Froschl G., Tiefenbacher R., Inayat-Hussain S.H., Cain K., Stopper H. Microsc. Res. Tech. 34:1996;247-258.
13. Inayat-Hussain S.h., Cohen G.M., Cain K. Cell Biol. Toxicol. 15:1999;381-387.
14. Piotto M., Saudek V., Sklenar V. J. Biomol. NMR. 2:1992;661-665.
15. Mountford C.E., Lean C.L., MacKinnon W.B. Annu. Rep. NMR Spectrosc. 27:1993;173-215.
16. Behar K.L., Ogino T. Magn. Reson. Med. 17:1991;285-303.
17. Romano R., Santini M.T., Indovina P.L. J. Magn. Reson. 146:2000;89-99.
18. Kotitschke K., Tonn J.C., Goldbrunner R., Bogdahn U., Haase A. J. Magn. Reson. 109:1995;39-43.
19. Nelder J.A., Mead R. Comput. J. 7:1965;308-313.
20. Caceci M.S., Cacheris W.P. BYTE. 5:1984;340-362.
21. Kirkpatrick S., Gelatt C.D., Vecchi M.P. Science. 220:1983;671-680.
22. Kirkpatrick S. J. Stat. Phys. 34:1984;975-986.
23. Metropolis N., Rosenbluth A., Rosenbluth M., Teller A., Teller E. J. Chem. Phys. 21:1953;1087-1092.
24. Press, W.H., Teukolsky, S.A., Wetterling, W.T. and Flannery, B.P. (1986) Numerical Recipes in C: The Art of Scientific Computing, 2nd edn., Cambridge University Press, Cambridge.
25. Romano R., Motta A., Camassa S., Pagano C., Santini M.T., Indovina P.L. J. Magn. Reson. 155:2002;226-235.
26. Fan T.W.-M. Prog. Magn. Reson. 28:1996;161-219.
27. van den Boogart A., Ala-Korpela M., Jokisaari J., Griffiths J.R. Magn. Reson. Med. 31:1994;347-358.
28. Ross, S.M. (1987) Introduction to Probability and Statistics for Engineers and Scientists, John Wiley and Sons, New York.
29. Eadie, W.T., Drijard, D., James, F.E., Ross, M. and Sadoulet, B. (1971) Statistical Methods in Experimental Physics, North Holland Publishing Company, Amsterdam.
30. Minard K.R., Guo X., Wind R.A. J. Magn. Reson. 133:1998;368-373.
31. Ronen S.M., Stier A., Degani H. FEBS Lett. 266:1990;147-149.
32. Bloom M., Holmes K.T., Mountford C.E., Williams P.G. J. Magn. Reson. 69:1986;73-91.
33. Mountford C.E., Tattersall M.H.N. Cancer Surv. 6:1987;285-314.
34. May J.L., Wright L.C., Holmes K.T., Williams P.G., Smith I.C.P., Wright P.E., Fox R.M., Mountford C.E. J. Biol. Chem. 261:1986;3048-3053.
35. LeMoyec L., Tatoud R., Eugene M., Gauville C., Primot I., Charlemagne D., Calvo F. Br. J. Cancer. 66:1992;626-628.
36. Hakumäki J.M., Kauppinen R.A. Trends Biochem. Sci. 25:2000;357-362.
37. Dang C.V., Semenza G.L. Trends Biochem. Sci. 24:1999;68-72.
38. Nelson B.D., Kabir F. Biochimie. 68:1986;407-415.