Telomerase activity and Bcl-2 expression in gallbladders of pancreaticobiliary maljunction patients: A preliminary study

Journal of Hepato-Biliary-Pancreatic Surgery

Volumn 11, Issue 1, 2004, Pages 34-39

  Ichikawa, Yasushi ^a   Kamiyama, Masako ^a   Sekido, Hitoshi ^a   Ishikawa, Takashi ^a   Miura, Yasuhiko ^a   Kamiya, Noriyuki ^a   Morita, Tomoyuki ^a   Shimada, Hiroshi ^a  

^a YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

Bcl 2; Pancreaticobiliary maljunction; Telomerase

Indexed keywords

K RAS PROTEIN; KI 67 ANTIGEN; PROTEIN BCL 2; PROTEIN P53; TELOMERASE;

ARTICLE; BILIARY TRACT MALFORMATION; BILIARY TRACT SURGERY; CARCINOGENESIS; CHOLECYSTITIS; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME ACTIVATION; ENZYME ACTIVITY; GALLBLADDER CANCER; GALLBLADDER MUCOSA; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INCIDENCE; PANCREAS MALFORMATION; POINT MUTATION; PRECANCER; PROTEIN EXPRESSION;

GALLBLADDER; GALLBLADDER NEOPLASMS; HUMANS; IMMUNOHISTOCHEMISTRY; KI-67 ANTIGEN; POINT MUTATION; PRECANCEROUS CONDITIONS; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS P21(RAS); TELOMERASE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 1642444969     PISSN: 09441166     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00534-003-0860-9     Document Type: Article

References (24)

1. Kimura K, Ohta M, Saisho H, Unozawa T, Tsuchiya Y, Morita M, Ebara M, Matsunami S, Okubo K (1985) Association of gallbladder carcinoma and anomalous pancreaticobiliary ductal union. Gastroenterology 89:1258-1265
2. Miura Y, Ichikawa Y, Ishikawa T, Sekido H, Nakano A, Mitsuhashi M, Shimada H (1998) The elevated mRNA content as a potential indicator of precancerous states of the gallbladder mucosa in patients with pancreaticobiliary maljunction. Oncol Rep 5:845-851
3. Kim NW, Piatyszek MA, Prowse KR (1994) Specific association of human-telomerase activity with immortal cells and cancer. Science 266:2011-2015
4. Yashima K, Milchgrub S, Gallahon LS, Maitra A, Saboorian MH, Shay JW, Gazdar AF (1998) Telomerase enzyme activity and RNA expression during the multistage pathogenesis of breast carcinoma. Clin Cancer Res 4:229-234
5. Mandal M, Kumar R (1997) Bcl-2 modulates telomerase activity. J Biol Chem 272:14183-14187
6. Hisatomi H, Nagao K, Komatsu H (1997) Quantification of telomerase activity in human liver tissues by fluorescence-based TRAP analysis. Hepatol Res 7:35-42
7. Ohmura Y, Aoe M, Andou A, Shimizu N (2002) Telomerase activity and Bcl-2 expression in non-small cell lung cancer. Clin Cancer Res Aug 6:2980-2987
8. Hasegawa Y, Takeda S, Ichii S, Koizumi K, Maruyama M, Fujii A, Ohta H, Nakajima T, Okuda M, Baba S (1995) Detection of k-ras mutations in DNAs isolated from feces of patients with colorectal tumors by mutant-allele-specific amplification (MASA). Oncogene 10:1441-1445
9. Ohta T, Nagakawa T, Konishi K, Maeda K, Kato M, Akiyama T, Kanno M, Higashino Y, Konishi I, Miyazaki I (1987) Clinicopathological study on carcinoma of gall bladder associated with anomalous arrangement of pancreaticobiliary ductal system. Jpn J Gastroenterol Surg 20:1038-1044
10. Fearon ER, Vogelstein B (1990) A genetic model for colorectal tumorigenesis. Cell 61:759-767
11. Greider CW, Blackburn EH (1985) Identification of specific telomere terminal transferase activity in Tetrahymena extracts. Cell 43:405-413
12. Sugino T, Yoshida K, Bolodeoku J, Tahara H, Buley I, Manek S, Wells C, Goodison S, Ide T, Suzuki T, Tahara E, Tarin D (1996) Telomerase activity in human breast cancer and benign breast lesions; diagnostic application in clinical specimens, including fine needle aspiration. Int J Cancer 69:301-306
13. Tang R, Cheng AJ, Wang JY, Wang TCV (1998) Close correlation between telomerase expression and adenomatous polyp progression in multistep colorectal carcinogenesis. Cancer Res 58: 4052-4054
14. Tahara H, Nakanishi T, Kitamoto M, Nakashio R, Shay JW, Tahara E, Kajiyama G, Ide (1995) Telomerase activity in human liver tissue: Comparison between chronic liver disease and hepatocellular carcinomas. Cancer Res Jul 1;55(13):2734-2736
15. Chen Y, Sato M, Fujimura S, Endo C, Sakurada A, Aikawa H, Takahashi H, Tanita T, Kondo T, Saito Y, Sagawa M (1999) Expression of Bcl-2, Bax, and p53 proteins in carcinogenesis of squamous cell lung cancer. Anticancer Res 19(2B):1351-1356
16. Ioachim E, Assimakopoulos D, Agnantis NJ, Peschos D, Zissi A, Skevas A (1999) Altered patterns of retinoblastoma gene product expression in benign, premalignant and malignant epithelium of the larynx: An immunohistochemical study including correlation with p53, bcl-2 and proliferating indices. Anticancer Res 19:541-545
17. Zhang GJ, Kimijima I, Abe R, Kanno M, Katagata N, Hara K, Watanabe T, Tsuchiya A (1997) Correlation between the expression of apoptosis-related bcl-2 and p53 oncoproteins and the carcinogenesis and progression of breast carcinomas. Clin Cancer Res 3:2329-2335
18. Charlotte F, L'Hermine A, Martin N, Geleyn Y, Nollet M, Gaulard P, Zafrani ES (1994) Immunohistochemical detection of bcl-2 protein in normal and pathological human liver. Am J Pathol 144:460-465
19. Pezzella F, Gatter K (1995) What is the value of bcl-2 protein detection for histopathologists? Histopathology 26:89-93
20. Mandel M, Kumar R (1997) Bcl-2 modulates telomerase activity. J Biol Chem 272:14183-14187
21. Ishikawa T, Kamiyama M, Hisatomi H, Ichikawa Y, Momiyama N, Hamaguchi Y, Hasegawa S, Narita T, Shimada H (1999) Telomerase enzyme activity and RNA expression in Adriamycin-resistant human breast carcinoma MCF-7 cells. Cancer Lett 141:187-194
22. Itoi T, Watanabe H, Yoshikawa T, Ajioka Y, Nishikura K, Saito T (1996) K-ras mutation in gall bladder carcinomas in patients with anomolous arrangement of the pancreaticobiliary duct. Acta Med Biol 44:71-77
23. Matsubara T, Sakurai Y, Sasayama Y, Hori H, Ochiai M, Funabiki T, Matusmoto K, Hirono I (1996) K-ras point mutation in cancerous and noncancerous biliary epithelium in patients with pancreaticobiliary maljunction. Cancer 77:1752-1757
24. Itoi T, Watanabe H, Kasuya K, Takei K, Matsubayashi H, Yasuda A, Yoshikawa T (1996) Histopathology of precancerous lesion of the gall bladder. Tan To Sui 16:1-12 (in Japanese)