Striatal delivery of rAAV-hAADC to rats with preexisting immunity to AAV

Molecular Therapy

Volumn 9, Issue 3, 2004, Pages 403-409

  Sanftner, Laura M ^a   Suzuki, Brian M ^a   Doroudchi, Mohammad M ^a   Feng, Lan ^a   McClelland, Alan ^a   Forsayeth, John R ^a   Cunningham, Janet ^a  

^a Avigen Inc   (United States)

Author keywords

AAV hAADC; Adeno associated virus; Aromatic L amino acid decarboxylase; Brain; Neutralizing antibody response; Parkinson disease

Indexed keywords

AROMATIC LEVO AMINO ACID DECARBOXYLASE; BETA GALACTOSIDASE; BIOLOGICAL MARKER; CD11B ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; GROWTH HORMONE; NEUTRALIZING ANTIBODY; PARVOVIRUS VECTOR;

ANIMAL CELL; ANIMAL TISSUE; ANTIBODY TITER; ARTICLE; BRAIN TISSUE; CELL INFILTRATION; CENTRAL NERVOUS SYSTEM DISEASE; CONTROLLED STUDY; CORPUS STRIATUM; CORRELATION FUNCTION; DRUG DISTRIBUTION; DRUG INFUSION; DRUG INHIBITION; DRUG MEGADOSE; GENE EXPRESSION; GENE THERAPY; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNITY; IMMUNIZATION; IMMUNOHISTOCHEMISTRY; MICROMORPHOLOGY; NONHUMAN; PROTEIN ANALYSIS; RAT; STATISTICAL ANALYSIS; STEREOMETRY; STEREOTAXIS; TRANSGENE; VIRAL GENE DELIVERY SYSTEM; VIRUS RECOMBINANT;

ADENO-ASSOCIATED VIRUS;

EID: 1642443395     PISSN: 15250016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ymthe.2003.12.005     Document Type: Article

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