Medullary reticulospinal tract mediating a generalized motor inhibition in cats: III. Functional organization of spinal interneurons in the lower lumbar segments

Neuroscience

Volumn 121, Issue 3, 2003, Pages 731-746

  Takakusaki, K ^a   Kohyama, J ^a,c   Matsuyama, K ^b  

^a ASAHIKAWA MEDICAL COLLEGE   (Japan)

^b SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

ABSm; Anterior biceps semimembranosus; CDPs; Cord dorsum potentials; Deep peroneal; DP; EDL; EPSPs; Excitatory postsynaptic potentials; Extensor digitorum longus; FDL; Locomotion; Medullary reticulospinal tract; Muscle tone; REM sleep; Spinal interneurons

Indexed keywords

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN DEPTH STIMULATION; CAT; CELL ACTIVITY; CONTROLLED STUDY; EVOKED RESPONSE; EXTRACELLULAR SPACE; FEMALE; FLEXOR REFLEX; INHIBITION KINETICS; INTERNEURON; INTRACELLULAR SPACE; LATENT PERIOD; LOCOMOTION; LUMBAR SPINE; MALE; MEDULLA OBLONGATA; MOTONEURON; MUSCLE TONE; NERVE CELL STIMULATION; NONHUMAN; PRIORITY JOURNAL; RETICULOSPINAL TRACT; RETICULUM CELL; SPINAL CORD NERVE CELL;

AFFERENT PATHWAYS; ANIMALS; CATS; CELL COUNT; ELECTRIC STIMULATION; EXCITATORY POSTSYNAPTIC POTENTIALS; INTERNEURONS; LUMBOSACRAL REGION; MEMBRANE POTENTIALS; MOTOR NEURONS; NEURAL INHIBITION; REACTION TIME; RETICULAR FORMATION; SPINAL CORD;

EID: 1642398096     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(03)00542-6     Document Type: Article

References (76)

1. Alxander G.E., Crutcher M.D. Functional architecture of basal ganglia circuits neural substrates of parallel processing. Trends Neurosci. 13:1990;267-271.
2. Appelberg B., Hulliger M., Johansson H., Sojka P. Actions on gamma motoneurons elicited by electrical stimulation of group II muscle afferent fibres in the hind limb of the cat. J Physiol. 335:1983;255-273.
3. Arduini A., Berlucchi B., Strata P. Pyramidal activity during sleep and wakefulness. Arch Ital Biol. 101:1963;530-544.
4. Basbaum A.L., Clanton C.H., Fields H.L. Three bulbospinal pathways from the rostral medulla of the cat an autoradiographic study of pain modulating systems. J Comp Neurol. 178:1978;209-224.
5. Beckstead R.M., Domesick V.B., Nauta W.J.H. Efferent connections of the substantia nigra and ventral tegmental area in the rat. Brain Res. 175:1979;191-217.
6. Berman A.L. Brain stem of the cat a cytoarchitectonic atlas with stereotaxic coordinates. 1968;University of Wisconsin Press, Madison.
7. Bizzi E., Pompeiano O., Somogyi I. Spontaneous activity of single vestibular neurons of unrestrained cats during sleep and wakefulness. Arch Ital Biol. 102:1964;308-330.
8. Bradley K., Eccles J.C. Analysis of the fast afferent impulses from thigh muscles. J Physiol. 122:1953;462-463.
9. Brink E., Harrison P.J., Jankowska E., McCrea D., Skoog B. Postsynaptic potentials in a population of motoneurones following activity of single interneurones in the cat. J Physiol. 343:1983;341-359.
10. Brink E., Jankowska E., McCrea D.A., Skoog B. Inhibitory interactions between interneurones in reflex pathways from group Ia and group Ib afferents in the cat. J Physiol. 343:1983;361-373.
11. Carol A.P., Jordan L.M. Ia inhibitory interneurons and Renshaw cells as contributors to the spinal mechanisms of fictive locomotion. J Neurophysiol. 57:1987;56-71.
12. Cavallari P., Edgley S.A., Jankowska E. Post-synaptic actions of midlumbar interneurones on motoneurons of hind-limb muscles in the cat. J Physiol. 389:1987;675-690.
13. Chase M.H., Morales F.R. The atonia and myoclonia of active (REM) sleep. Annu Rev Psychol. 41:1990;557-584.
14. Chase M.H., Morales F.R., Boxer P., Fung S.J., Soja P.J. Effect of stimulation of the nucleus reticularis gigantocellularis on the membrane potential of cat lumbar motoneurons during sleep and wakefulness. Brain Res. 386:1986;237-244.
15. Coppin C.M.L., Jack J.J.B., McIntyre A.K. Properties of group I afferent fibres from semitendinosus muscle in the cat. J Physiol. 303:1969;45-46.
16. Czarkowska J., Jankowska E., Sybirska E. Common interneurones in reflex pathways from group Ia and Ib afferents of knee flexors and extensors in the cat. J Physiol. 310:1981;367-380.
17. Delong M.R. Primate models of movement disorders of basal ganglia origin. Trends Neurosci. 13:1990;281-289.
18. Delwaide P.J. Parkinsonian rigidity. Funct Neurol. 16:2001;147-156.
19. Drew T. Functional organization within the medullary reticular formation of the intact unanesthetized cat III. Microstimulation during locomotion. J Neurophysiol. 66:1991;919-938.
20. Drew T., Rossignol S. Functional organization within the medullary reticular formation of intact unanesthetized cat II. Electromyographic activity evoked by microstimulation. J Neurophysiol. 64:1990;782-795.
21. Drew T., Dubuc R., Rossignol S. Discharge patterns of reticulospinal and other reticular neurons in chronic, unrestrained cats walking on a treadmill. J Neurophysiol. 55:1986;375-401.
22. Eccles J.C., Eccles R.M., Iggo A., Lundberg A. Electrophysiological investigations on Renshaw cells. J Physiol. 159:1961;461-478.
23. Edgley S.A., Jankowska E. Field potentials generated by group I and II muscle afferents in the middle lumbar segments of the cat spinal cord. J Physiol. 385:1987;393-413.
24. Edgley S.A., Jankowska E., Shefchyk S. Evidence that interneurones in reflex pathways from group II afferents are involved in locomotion in the cat. J Physiol. 403:1988;57-73.
25. Feldman A.G., Orlovsky G.N. Activity of interneurons mediating reciprocal Ia inhibition during locomotion. Brain Res. 84:1975;181-194.
26. Glenn L.L., Dement W.C. Membrane potential, synaptic activity, and excitability of hindlimb motoneurons during wakefulness and sleep. J Neurophysiol. 46:1981;839-854.
27. Glenn L.L., Dement W.C. Membrane resistance and rheobase of hindlimb motoneurons during wakefulness and sleep. J Neurophysiol. 46:1981;1076-1088.
28. Glenn L.L., Dement W.C. Group I excitatory and inhibitory potentials in hindlimb motoneurons during wakefulness and sleep. J Neurophysiol. 46:1981;1089-1101.
29. Grantyn A., Berthoz A. Reticulospinal neurons participating in the control of synergic eye movements during orienting in the cat I. Behavioral properties. Expl Brain Res. 66:1987;339-354.
30. Habaguchi T., Takakusaki K., Saitoh K., Sugimoto J., Sakamoto T. Medullary reticulospinal tract mediating the generalized motor inhibition in cats II. Functional organization within the medullary reticular formation with respect to postsynaptic inhibition of forelimb and hindlimb motoneurons. Neuroscience. 113:2002;65-77.
31. Hentall I.D., Zorman G., Kansky S., Fields H.L. Relations among threshold, spike height, electrode distance, and conduction velocity in electrical stimulation of certain medullospinal neurons. J Neurophysiol. 51:1984;968-977.
32. Hongo T., Jankowska E., Lundberg A. The rubrospinal tract II. Facilitation of interneuronal transmission in reflex paths to motoneurons. Expl Brain Res. 7:1969;365-391.
33. Hongo T., Jankowska E., Lundberg A. The rubrospinal tract IV. Effects on interneurones. Expl Brain Res. 15:1972;54-78.
34. Hongo T., Jankowska E., Ohno T., Sasaki S., Yamashita M., Yoshida K. The same interneurones mediate inhibition of dorsal spinocerebellar tract cells and lumbar motoneurones in the cat. J Physiol. 342:1983;161-180.
35. Hultborn H., Illert M., Santini M. Convergence on interneurones mediating the reciprocal Ia inhibition of motoneurones III. Effects from supraspinal pathways. Acta Physiol Scand. 96:1976;368-391.
36. Hultborn H., Jankowska E., Lindstrom S. Recurrent inhibition from motor axon collaterals of transmission in the Ia inhibitory pathway to motoneurones. J Physiol. 215:1971;591-612.
37. Hultbon H., Jankowska E., Lindstrom S. Recurrent inhibition of interneurones monosynaptically activated from group I afferents. J Physiol. 215:1971;613-636.
38. Isa T., Naito K. Activity of neurons in the medial pontomedullary reticular formation during orienting movements in alert head-free cats. J Neurophysiol. 74:1995;73-95.
39. Jankowska E. Interneuronal relay in spinal pathways from proprioceptors. Prog Neurobiol. 38:1992;335-378.
40. Jankowska E., Johannisson T., Lipski J. Common interneurones in reflex pathways from group Ia and Ib afferents of ankle extensors in the cat. J Physiol. 310:1981;381-402.
41. Jankowska E., Lund S., Lundberg A., Pompeiano O. Inhibitory effects evoked by through ventral reticulospinal pathways. Arch Ital Biol. 106:1968;124-140.
42. Jankowska E., McCrea D., Mackel R. Pattern of non-reciprocal inhibition of motoneurones by impulses in group Ia muscle spindle afferents. J Physiol. 316:1981;393-409.
43. Jankowska E., Padel Y., Tanaka R. Disynaptic inhibition of spinal motoneurones from the motor cortex in the monkey. J Physiol. 258:1976;467-487.
44. Kohyama J., Lai Y.Y., Siegel J.M. Reticulospinal systems mediate atonia with short and long latencies. J Neurophysiol. 80:1998;1839-1851.
45. Llinás R., Terzuolo C.A. Mechanisms of supraspinal actions upon spinal cord activities reticular inhibitory mechanisms on alpha-extensor motoneurons. J Neurophysiol. 27:1964;579-591.
46. Llinás R., Terzuolo C.A. Mechanisms of supraspinal actions upon spinal cord activities reticular inhibitory mechanisms upon flexor motoneurons. J Neurophysiol. 28:1965;413-422.
47. Lundberg A., Malmgren K., Schomburg E.D. Reflex pathways from group II muscle afferents I. Distribution and linkage of reflex actions of α-motoneurons. Expl Brain Res. 65:1987;294-306.
48. Lundberg A., Malmgren K., Schomburg E.D. Reflex pathways from group II muscle afferents III. Secondary spindle afferents and the FRA: a new hypothesis. Expl Brain Res. 65:1987;294-306.
49. Lundberg A., Norrsell U., Vooehoeve P. Pyramidal effects on lumbo-sacral interneurones activated by somatic afferents. Acta Physiol Scand. 56:1962;220-229.
50. Lundberg A., Voorhoeve P. Effects from the pyramidal tract on spinal reflex arcs. Acta Physiol Scand. 56:1962;201-219.
51. McCrea D.A., Carol A.P., Jordan L.M. Renshaw cell activity and recurrent effects on motoneurons during fictive locomotion. J Neurophysiol. 44:1980;475-488.
52. Magoun M.W., Rhines R. An inhibitory mechanism in the bulbar reticular formation. J Neurophysiol. 9:1946;165-171.
53. Matsuyama K., Kobayashi Y., Takakusaki K., Mori S., Kimura H. Termination mode and branching patterns of reticuloreticular and reticulospinal fibers of the nucleus reticularis pontis oralis in the cat an anterograde PHA-L tracing study. Neurosci Res. 17:1993;9-21.
54. Matsuyama K., Ohta Y., Mori S. Ascending and descending projections of the nucleus reticularis gigantocellularis in the cat demonstrated by the anterograde neural tracer, Phaseolus vulgaris leucoagglutinin (PHA-L). Brain Res. 460:1988;124-141.
55. Mitani A., Ito K., Mitani Y., McCarley R.W. Descending projections from the gigantocellular tegmental field in the cat cells of origin and their brainstem and spinal cord trajectories. J Comp Neurol. 268:1988;546-566.
56. Morales F.R., Chase M.H. Intracellular recording of lumbar motoneuron membrane potential during sleep and wakefulness. Expl Neurol. 62:1978;821-827.
57. Mori S. Integration of posture and locomotion in acute decerebrate cats and in awake, freely moving cats. Prog Neurobiol. 28:1987;161-196.
58. Moriizumi T., Nakamura Y., Tokuno H., Kitao Y., Kudo M. Topographic projections from the basal ganglia to the nucleus tegmenti pedunculopontinus pars compacta of the cat with special reference to pallidal projections. Expl Brain Res. 71:1988;298-306.
59. Noga B.R., Schefchyk S.J., Jamal J., Jordan L.M. The role of Renshaw cells in locomotion antagonism of their excitation from motor axon collaterals with intravenous mecamylamine. Expl Brain Res. 66:1987;99-105.
60. Peterson B.W. The reticulospinal system and its role in the control of movement. Barnes C.D. Brainstem control of spinal cord function. 1984;27-36 Academic Press, London.
61. Peterson B.W., Pitts N.G., Fukushima K. Reticulospinal connections with limb and axial motoneurons. Expl Brain Res. 36:1979;1-20.
62. Peterson B.W., Pitts N.G., Fukushima K., Mackel R.G. Reticulospinal excitation and inhibition of neck motoneurons. Expl Brain Res. 32:1978;471-489.
63. Renshaw B. Central effects of centripetal impulses in axons of spinal ventral roots. J Neurophysiol. 9:1946;191-204.
64. Rhines R., Magoun M.W. Brain stem facilitation of cortical motor responses. J Neurophysiol. 9:1946;219-229.
65. Rudomin P., Soldokin M., Jimenez I. Synaptic potentials of primary afferent fibers and motoneurons evoked by single intermediate nucleus interneurons in the cat spinal cord. J Neurophysiol. 57:1987;1288-1313.
66. Rye B.D., Saper C.B., Lee H.J., Wainer B.H. Pedunculopontine tegmental nucleus of the rat cytoarchitecture, cytochemistry, and some extrapyramidal connections of the mesopontine tegmentum. J Comp Neurol. 259:1987;483-528.
67. Schefchyk S., Jell R.M., Jordan L.M. Reversal cooling of the brainstem reveals areas required for mesencephalic locomotor region evoked treadmill locomotion. Expl Brain Res. 56:1984;257-262.
68. Schefchyk S., McCrea D., Kriellaars P., Fortier P., Jordan L.M. Activity of interneurons within the L4 spinal segment of the cat during brain-stem evoked fictive locomotion. Expl Brain Res. 80:1990;290-295.
69. Snider R.S., Niemer W.T. A stereotaxic atlas of the cat brain. 1961;University of Chicago Press, Chicago.
70. Spann B.M., Grofova I. Nigro-pedunculopontine projection in the rat an anterograde tracing study with Phaseolus vulgaris-leucoagglutinin (PHA-L). J Comp Neurol. 311:1991;375-388.
71. Sprague J.M., Chambers W.W. Control of posture by reticular formation and cerebellum in the intact, anesthetized and unanesthetized and in the decerebrated cat. Am J Physiol. 176:1954;52-64.
72. Takakusaki K. Reticulospinal control of interneurons in relation to the production of generalized motor inhibition in cats. Soc Neurosci Abstr. 24:1998;951.
73. Takakusaki K., Habaguchi T., Ohtinata-Sugimoto J., Saitoh K., Sakamoto T. Basal ganglia efferents to the brainstem centers controlling postural muscle tone and locomotion a new concept for understanding motor disorders in basal ganglia dysfunction. Neuroscience. 119:2003;293-308.
74. Takakusaki K., Kohyama J., Matsuyama K., Mori S. Discharge properties of medullary reticulospinal neurons during postural changes induced by intra-pontine injections of carbachol, atropine and serotonin, and their functional linkages to hindlimb motoneurons in cats. Expl Brain Res. 99:1994;361-374.
75. Takakusaki K., Kohyama J., Matsuyama K., Mori S. Medullary reticulospinal tract mediating the generalized motor inhibition in cats parallel inhibitory mechanisms acting on motoneurons and on interneuronal transmission in reflex pathways. Neuroscience. 103:2001;511-527.
76. Takakusaki K., Ohta Y., Mori S. Single medullary reticulospinal neurons exert postsynaptic inhibitory effects via inhibitory interneurons upon alpha-motoneurons innervating cat hindlimb muscles. Expl Brain Res. 74:1989;11-23.