Effect of glycine substitutions on α5(IV) chain structure and structure-phenotype correlations in Alport syndrome

Biochemical and Biophysical Research Communications

Volumn 316, Issue 4, 2004, Pages 1143-1149

  Wang, Yun Feng ^a   Ding, Jie ^a   Wang, Fang ^a   Bu, Ding Fang ^a  

^a PEKING UNIVERSITY FIRST HOSPITAL   (China)

Author keywords

Amino acid substitution; Circular dichroism; Collagen type IV; Genotype; Glycine; Nephritis, hereditary; Phenotype; Protein structure, secondary

Indexed keywords

GENOMIC DNA; GENOMIC RNA; GLYCINE; MESSENGER RNA; RECOMBINANT PROTEIN;

ALPHA CHAIN; ALPHA HELIX; ALPORT SYNDROME; ARTICLE; BIODIVERSITY; CIRCULAR DICHROISM; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE SEVERITY; ESCHERICHIA COLI; GENETIC IDENTIFICATION; IMMUNOBLOTTING; MASS SPECTROMETRY; MUTATION; NONHUMAN; ONSET AGE; PEDIGREE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN SECONDARY STRUCTURE; STRUCTURE ANALYSIS; X CHROMOSOME LINKAGE;

ADOLESCENT; ADULT; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CIRCULAR DICHROISM; COLLAGEN TYPE IV; ESCHERICHIA COLI; GLYCINE; HUMANS; MALE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NEPHRITIS, HEREDITARY; PHENOTYPE; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, PROTEIN; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP;

ESCHERICHIA COLI;

EID: 1642397346     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.02.168     Document Type: Article

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