Acute tryptophan depletion slows gastric emptying in females

British Journal of Nutrition

Volumn 91, Issue 3, 2004, Pages 351-355

  van Nieuwenhoven, Michiel A ^a   Valks, Sabine D M ^a   Sobczak, Sjacko ^a   Riedel, Willem J ^a   Brummer, Robert Jan M ^a  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Amino acids; Gastric emptying; Serotonin; Tryptophan depletion

Indexed keywords

CISAPRIDE; NEUROTRANSMITTER; OCTANOIC ACID; PLACEBO; SEROTONIN; SEROTONIN 4 AGONIST; SEROTONIN 4 RECEPTOR; TRYPTOPHAN; AMINO ACID;

ADULT; ARTICLE; BREATH ANALYSIS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DYSPEPSIA; FEMALE; GASTROINTESTINAL MOTILITY; HUMAN; HUMAN EXPERIMENT; NORMAL HUMAN; NUTRITION; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN SYNTHESIS INHIBITION; QUANTITATIVE ANALYSIS; RANDOMIZED CONTROLLED TRIAL; SEROTONINERGIC SYSTEM; SEX DIFFERENCE; STOMACH EMPTYING; VOLUNTEER; BLOOD; METHODOLOGY; PHYSIOLOGY;

ADULT; AMINO ACIDS; BREATH TESTS; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; FEMALE; GASTRIC EMPTYING; HUMANS; SEROTONIN; TRYPTOPHAN;

EID: 1642388319     PISSN: 00071145     EISSN: None     Source Type: Journal    
DOI: 10.1079/BJN20031055     Document Type: Article

References (27)

1. Bell C, Abrams J & Nutt D (2001) Tryptophan depletion and its implications for psychiatry. Br J Psych 178, 399-405.
2. Bouras EP, Camilleri M, Burton DD, Thomforde G, McKinzie S & Zinsmeister AR (2001) Prucalopride accelerates gastrointestinal and colonic transit in patients with constipation without a rectal evacuation disorder. Gastroenterology 120, 354-360.
3. Carpenter LL, Anderson GM, Pelton GH, Gudin JA, Kirwin PD, Price LH, Heninger GR & McDougle CJ (1998) Tryptophan depletion during continuous CSF sampling in healthy human subjects. Neuropsychopharmacology 19, 26-35.
4. Cooke AR & Ward WO (1976) Effect of tryptophan and its metabolites on gastric emptying of liquid meals in dogs. Proc Soc Exp Biol Med 152, 656-658.
5. Coulie B, Tack J, Maes B, Geypens B, De Roo M & Janssens J (1997) Sumatriptan, a selective 5-HT1 receptor agonist, induces a lag phase for gastric emptying of liquids in humans. Am J Physiol 272, G902-G908.
6. Ghoos YF, Maes BD, Geypens BJ, Mys G, Hiele MI, Rutgeerts PJ & Vantrappen G (1993) Measurement of gastric emptying rate of solids by means of a carbon-labeled octanoic acid breath test. Gastroenterology 104, 1640-1647.
7. Gore S, Gilmore IT, Haigh CG, Brownless SM, Stockdale H & Morris AI (1990) Colonic transit in man is slowed by ondansetron (GR38032F), a selective 5-hydroxytryptamine receptor (type 3) antagonist. Aliment Pharmacol Ther 4, 139-144.
8. Haug TT, Svebak S, Hausken T, Wilhelmsen I, Berstad A & Ursin H (1994) Low vagal activity as mediating mechanism for the relationship between personality factors and gastric symptoms in functional dyspepsia. Psychosom Med 56, 181-186.
9. Houghton LA, Fowler P, Keene ON & Read NW (1992) Effect of sumatriptan, a new selective 5HT1-like agonist, on liquid gastric emptying in man. Aliment Pharmacol Ther 6, 685-691.
10. Jackson JL, O'Malley PG, Tomkins G, Balden E, Santoro J & Kroenke K (2000) Treatment of functional gastrointestinal disorders with antidepressant medications: a meta-analysis. Am J Med 108, 65-72.
11. Klaassen T, Riedel WJ, Deutz NE, van Someren A & van Praag HM (1999) Specificity of the tryptophan depletion method. Psychopharmacology (Berlin) 141, 279-286.
12. Maes BD, Ghoos YF, Hiele MI & Rutgeerts PJ (1997) Gastric emptying rate of solids in patients with nonulcer dyspepsia. Dig Dis Sci 42, 1158-1162.
13. Malagelada JR (1991) Gastrointestinal motor disturbances in functional dyspepsia. Scand J Gastroent 182, Suppl., 29-32.
14. Moore P, Landolt HP, Seifritz E, Clark C, Bhatti T, Kelsoe J, Rapaport M & Gillin JC (2000) Clinical and physiological consequences of rapid tryptophan depletion. Neuropsychopharmacology 23, 601-622.
15. Nielsen OH, Hvid-Jacobsen K, Lund P & Langoholz E (1990) Gastric emptying and subjective symptoms of nausea: lack of effects of a 5-hydroxytryptamine-3 antagonist ondansetron on gastric emptying in patients with gastric stasis syndrome. Digestion 46, 89-96.
16. Nishizawa S, Benkelfat C, Young SN, Leyton M, Mzengeza S, de Montigny C, Blier P & Diksic M (1997) Differences between males and females in rates of serotonin synthesis in human brain. Proc Natl Acad Sci USA 94, 5308-5313.
17. Riedel WJ, Klaassen T, Deutz NE, van Someren A & van Praag HM (1999) Tryptophan depletion in normal volunteers produces selective impairment in memory consolidation. Psychopharmacology (Berlin) 141, 362-369.
18. Schmitt JA, Jorissen BL, Sobczak S, van Boxtel MP, Hogervorst E, Deutz NE & Riedel WJ (2000) Tryptophan depletion impairs memory consolidation but improves focussed attention in healthy young volunteers. J Psychopharmacol 14, 21-29.
19. Sobczak S (2002) Serotonin and Bipolar Disorders, PhD thesis, Maastricht University, The Netherlands.
20. Tack J, Piessevaux H, Coulie B, Caenepeel & Janssens J (1998) Role of impaired gastric accommodation to a meal in functional dyspepsia. Gastroenterology 115, 1346-1352.
21. Thumshirn M, Coulie B, Camilleri M, Zinsmeister AR, Burton DD & Van Dyke C (2000) Effects of alosetron on gastrointestinal transit time and rectal sensation in patients with irritable bowel syndrome. Aliment Pharmacol Ther 14, 869-878.
22. Tonini M, Galligan JJ & North RA (1989) Effects of cisapride on cholinergic neurotransmission and propulsive motility in the guinea pig ileum. Gastroenterology 96, 1257-1264.
23. Van der Does AJ (2001) The effects of tryptophan depletion on mood and psychiatric symptoms. J Affect Disord 64, 107-119.
24. Van Eijk HM, Rooyakkers DR & Deutz NE (1993) Rapid routine determination of amino acids in plasma by high-performance liquid chromatography with a 2-3 microns Spherisorb ODS II column. J Chromatogr 620, 143-148.
25. Veldhuyzen van Zanten SJ, Jones MJ, Verlinden M & Talley NJ (2001) Efficacy of cisapride and domperidone in functional (nonulcer) dyspepsia: a meta-analysis. Am J Gastroenterol 96, 689-696.
26. Waldron B, Cullen PT, Kumar R, Smith D, Jankowski J, Hopwood D, Sutton D, Kennedy N & Campbell FC (1991) Evidence for hypomotility in non-ulcer dyspepsia: a prospective multifactorial study. Gut 32, 246-251.
27. Young SN, Leyton M & Benkelfat C (1999) Pet studies of serotonin synthesis in the human brain. Adv Exp Med Biol 467, 11-18.