Effects of the order exposure to a binary mixture of mutagens on the induced mutation spectra in the supF gene

Mutagenesis

Volumn 19, Issue 2, 2004, Pages 137-141

  McLuckie, Keith I E ^b   Gaskell, Margaret ^d   Farmer, Peter B ^d   Martin, Elizabeth A ^c   Jones, George D D ^a   Routledge, Michael N ^b  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b UNIVERSITY OF LEEDS   (United Kingdom)

^c ASTRAZENECA   (United Kingdom)

^d UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROXYBENZO[A]PYRENE OXIDE; MUTAGENIC AGENT;

ARTICLE; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; DNA SEQUENCE; EMBRYO; GENE MUTATION; HUMAN; HUMAN CELL; MUTAGENICITY; MUTATION RATE; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; SHUTTLE VECTOR; ULTRAVIOLET C RADIATION;

7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE 9,10-OXIDE; BASE SEQUENCE; ESCHERICHIA COLI; GENES, SUPPRESSOR; MOLECULAR SEQUENCE DATA; MUTAGENS; MUTATION; RNA, TRANSFER; ULTRAVIOLET RAYS;

EID: 1642376441     PISSN: 02678357     EISSN: None     Source Type: Journal    
DOI: 10.1093/mutage/geh011     Document Type: Article

References (20)

1. Bigger,C.A.H., Ponten,I., Page,J.E. and Dipple,A. (2000) Mutational spectra for polycyclic aromatic hydrocarbons in the supF target gene. Mutat. Res., 450, 75-93.
2. Brash,D.E., Seetharam,S., Kraemer,K.H., Seidman,M.M. and Bredberg,A. (1987) Photoproduct frequency is not the major determinant of UV base substitution hot spots or cold spots in human cells. Proc. Natl Acad. Sci. USA, 84, 3782-3786.
3. Canella,K.A. and Seidman,M.M. (2000) Mutation spectra in supF: Approaches to elucidating sequence context effects. Mutat. Res., 450, 61-73.
4. Cariello,N.F., Piegorsch,W.W., Adams,W.T. and Skopek,T.R. (1994) Computer program for the analysis of mutational spectra: application to p53 mutations. Carcinogenesis, 15, 2281-2285.
5. Courtemanche,C. and Anderson.A. (1994) Shuttle-vector mutagenesis by aflatoxin B-1 in human cells - effects of sequence context on the supF mutational spectrum. Mutat. Res., 306, 143-151.
6. Deflora,S., Vigano,L., Dagostini,F., Camoirano,A., Bagnasco,M., Bennicelli,C., Melodia,F. and Arillo,A. (1993) Multiple genotoxicity biomarkers in fish exposed in-situ to polluted river water. Murat. Res., 319, 167-177.
7. DeMarini,D.M. (1998) Mutation spectra of complex mixtures. Mutat. Res., 411, 11-18.
8. Graham,F.L. and Van der Eb,A.J. (1973) A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology, 52, 456-467.
9. Houk,V.S. (1992) The genotoxicity of industrial-wastes and effluents. Mutat. Res., 277, 91-138.
10. Hussain,S.P. and Harris,C.C. (2000) Molecular epidemiology and carcinogenesis: Endogenous and exogenous carcinogens. Mutat. Res., 462, 311-322.
11. 1-induced mutations in a plasmid replicated in xeroderma-pigmentosum and DNA-repair proficient human cells. Cancer Res., 52, 5668-5673.
12. Levy,D.D., Magee,A.D. and Seidman,M.M. (1996) Single nuclecitide positions have proximal and distal influence on UV mutation hotspots and coldspots. J. Mol. Biol., 258, 251-260.
13. Parris,C.N. and Seidman,M.M. (1992) A signature element distinguishes sibling and independent mutations in a shuttle vector plasmid. Gene, 117, 1-5.
14. Rank,J., Folke,J. and Jespersen,P.H. (2001) Differences in cyclists and car drivers' exposure to air pollution from traffic in the city of Copenhagen. Sci. Total Environ., 279, 131-136.
15. Routledge,M.N., McLuckie,K.I.E., Jones,G.D.D., Farmer,P.B. and Martin,E.A. (2001) Presence of benzo[a]pyrene diol epoxide adducts in target DNA leads to an increase in UV-induced DNA single strand breaks and supF gene mutations. Carcinogenesis, 22, 1231-1238.
16. Seidman,M.M., Dixon,K., Razzaque,A., Zagursky,R.J. and Berman,M.L. (1985) A shuttle vector plasmid for studying carcinogen-induced point mutations in mammalian cells. Gene, 38, 233-237.
17. Seidman,M.M., Bredberg,A., Seetharam,S. and Kraemer,K.H. (1987) Multiple point mutations in a shuttle vector propagated in human-cells - evidence for an error-prone DNA-polymerase-activity. Proc. Natl Acad. Sci. USA, 84, 4944-4948.
18. Seo,K.-Y., Jelinsky,S.A. and Loechler,E.L. (2000) Factors that influence the mutagenic patterns of DNA adducts from chemical carcinogens. Mutat. Res., 463, 215-246.
19. Viskari,E.L., Rekila,R., Roy,S., Lehto,O., Ruuskanen,J. and Karenlampi,L. (1997) Airborne pollutants along a roadside: Assessment using snow analyses and moss bags. Environ. Pollut., 97, 153-160.
20. White,P.A., Rasmussen,J.B. and Blaise,C. (1996) Comparing the presence, potency and potential hazard of genotoxins extracted from a broad range of industrial effluents. Environ. Mol. Mutagen., 27, 116-139.