Synthesis and Biological Evaluation of Novel Chloroethylaminoanthraquiones with Potent Cytotoxic Activity against Cisplatin-Resistant Tumor Cells

Journal of Medicinal Chemistry

Volumn 47, Issue 7, 2004, Pages 1856-1859

  Pors, Klaus ^a   Paniwnyk, Zennia ^b   Ruparelia, Ketan C ^b   Teesdale Spittle, Paul H ^b   Hartley, John A ^c   Kelland, Lloyd R ^d   Patterson, Laurence H ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b DE MONTFORT UNIVERSITY   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

1 [[2 [BIS(2 CHLOROETHYL)AMINO]ETHYL]AMINO] 4 [2 (DIMETHYLAMINO)ETHYL]AMINO 5,8 DIHYDROXYANTHRACENE 9,10 DIONE; ANTHRAQUINONE DERIVATIVE; ANTINEOPLASTIC AGENT; CHLORAMBUCIL; CHLOROETHYLAMINOANTHRAQUINONE DERIVATIVE; CISPLATIN; EPIRUBICIN; GUANINE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; CANCER RESISTANCE; CONTROLLED STUDY; CYTOTOXICITY; DNA BINDING; DNA CROSS LINKING; HUMAN; HUMAN CELL; OVARY TUMOR;

ANTHRAQUINONES; ANTINEOPLASTIC AGENTS, ALKYLATING; CELL LINE, TUMOR; CISPLATIN; DNA; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 1642349309     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm031070u     Document Type: Article

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