Central and peripheral mechanisms contribute to the antiemetic actions of delta-9-tetrahydrocannabinol against 5-hydroxytryptophan-induced emesis

European Journal of Pharmacology

Volumn 488, Issue 1-3, 2004, Pages 201-212

  Darmani, Nissar A ^a   Johnson, Jane C ^a  

^a A T STILL UNIVERSITY   (United States)

Author keywords

5 HT; 5 HTP; Cannabinoid CB1 receptor; Carbidopa; Central; Delta 9 THC; Ear scratch; Head twitch; Peripheral; SR 141716A

Indexed keywords

2 METHYLSEROTONIN; 5 HYDROXYTRYPTOPHAN; ANTIEMETIC AGENT; CANNABINOID 1 RECEPTOR; CANNABINOID RECEPTOR ANTAGONIST; CARBIDOPA; DRONABINOL; RIMONABANT; SEROTONIN; SEROTONIN 3 AGONIST;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; DRUG MEGADOSE; FEMALE; HEAD TWITCH; INSECTIVORE; LOW DRUG DOSE; MALE; NONHUMAN; POSTSYNAPTIC INHIBITION; PRESYNAPTIC INHIBITION; PRIORITY JOURNAL; SCRATCHING; VOMITING;

5-HYDROXYTRYPTOPHAN; ANIMALS; ANTIEMETICS; BEHAVIOR, ANIMAL; CARBIDOPA; CENTRAL NERVOUS SYSTEM; DOPAMINE AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; EMETICS; FEMALE; MALE; PERIPHERAL NERVOUS SYSTEM; PIPERIDINES; PYRAZOLES; RECEPTOR, CANNABINOID, CB1; SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; SHREWS; TETRAHYDROCANNABINOL;

EID: 1642303039     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.02.018     Document Type: Article

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