Somatic treatment of bipolar disorder in children and adolescents

Psychiatric Clinics of North America

Volumn 27, Issue 1, 2004, Pages 155-178

  Weller, Elizabeth B ^a   Danielyan, Arman K ^b   Weller, Ronald A ^b  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; CALCIUM CHANNEL BLOCKING AGENT; CARBAMAZEPINE; CHLORPROMAZINE; CLOZAPINE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GABAPENTIN; LAMOTRIGINE; LEVOTHYROXINE; LITHIUM; NEUROLEPTIC AGENT; NIMODIPINE; NONSTEROID ANTIINFLAMMATORY AGENT; OLANZAPINE; OMEGA 3 FATTY ACID; PSYCHOTROPIC AGENT; QUETIAPINE; RISPERIDONE; SERTRALINE; TRICYCLIC ANTIDEPRESSANT AGENT; VALPROATE SEMISODIUM; VALPROIC ACID; XANTHINE DERIVATIVE;

AGITATION; AGRANULOCYTOSIS; ALOPECIA; APLASTIC ANEMIA; ATAXIA; BIOAVAILABILITY; BIPOLAR I DISORDER; BIPOLAR II DISORDER; BLOOD DYSCRASIA; BRAIN FUNCTION; CARDIOVASCULAR DISEASE; CARNITINE DEFICIENCY; CLINICAL TRIAL; COMA; DEATH; DIARRHEA; DISEASE ASSOCIATION; DROWSINESS; DRUG EFFICACY; ELECTROCONVULSIVE THERAPY; ENURESIS; EYE DISEASE; FATIGUE; FEVER; FOCAL EPILEPSY; HEADACHE; HEMATOLOGIC DISEASE; HUMAN; HYPERAMMONEMIA; HYPERGLYCEMIA; INCREASED APPETITE; INSOMNIA; IRRITABILITY; KIDNEY DISEASE; LETHARGY; LEUKOCYTOSIS; LIVER DISEASE; LIVER TOXICITY; LONG TERM CARE; LONGITUDINAL STUDY; MAJOR DEPRESSION; MALAISE; MANIA; MEDICAL EXAMINATION; MEDICAL LITERATURE; MEDICAL RESEARCH; MENSTRUATION DISORDER; MENTAL INSTABILITY; MUSCLE WEAKNESS; NAUSEA; NEURAL TUBE DEFECT; NEUROLOGIC DISEASE; ONSET AGE; PANCREAS DISEASE; PANCREATITIS; POLYDIPSIA; POLYURIA; PRIORITY JOURNAL; PROBABILITY; PSYCHOPHARMACOLOGY; RANDOMIZATION; RETROSPECTIVE STUDY; REVIEW; SALIVATION DISORDER; SEDATION; SEIZURE; SORE THROAT; THYROID DISEASE; TREMOR; VERTIGO; VOMITING; WEIGHT GAIN;

ADOLESCENT; ANTIPSYCHOTIC AGENTS; BIPOLAR DISORDER; CHILD; DRUG ADMINISTRATION SCHEDULE; ELECTROCONVULSIVE THERAPY; HUMANS;

EID: 1642285782     PISSN: 0193953X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0193-953X(03)00116-3     Document Type: Review

References (167)

1. American Academy of Child and Adolescent Psychiatry. Practice parameters for the assessment and treatment of children and adolescents with bipolar disorder. J Am Acad Child Adolesc Psychiatry. 36:1997;138-157.
2. Fetner H.H., Geller B. Lithium and tricyclic antidepressants. Psychiatr Clin North Am. 15:1992;223-224.
3. Youngerman J., Canino I.A. Lithium carbonate use in children and adolescents: a survey of the literature. Arch Gen Psychiatry. 35:1978;216-224.
4. Kafantaris V. Treatment of bipolar disorder in children and adolescents. J Am Acad Child Adolesc Psychiatry. 34:1995;732-741.
5. Weller E. Bipolar children and adolescents: controversies in diagnosis and treatment. Proceedings of the American Psychiatric Association 153rd Annual Meeting. Chicago (IL); 2000.
6. Strober M., Morrell W., Lampert C., et al. Relapse following discontinuation of lithium maintenance therapy in adolescents with bipolar I illness: a naturalistic study. Am J Psychiatry. 147:1990;457-461.
7. Carlson G.A., Rapport M.D., Pataki C.S., et al. Lithium in hospitalized children at 4 and 8 weeks: mood, behavior and cognitive effects. J Child Psychol Psychiatry. 33:1992;411-425.
8. Varanka T.M., Weller R.A., Weller E.B., et al. Lithium treatment of manic episodes with psychotic features in prepubertal children. Am J Psychiatry. 145:1988;1557-1559.
9. Geller B., Cooper T.B., Sun K., et al. Double-blind and placebo-controlled study of lithium for adolescent bipolar disorders with secondary substance dependency. [see comments] J Am Acad Child Adolesc Psychiatry. 37:1998;171-178.
10. Kowatch R.A., Suppes T., Carmody T.J., et al. Effect size of lithium, divalproex sodium, and carbamazepine in children and adolescents with bipolar disorder. J Am Acad Child Adolesc Psychiatry. 39:2000;713-720.
11. Lin K.M., Anderson D., Poland R.E. Ethnicity and psychopharmacology. Bridging the gap. Psychiatr Clin North Am. 18:1995;635-647.
12. Goodwin F., Jamison K. Manic-depressive illness. 1990;Oxford University Press, New York (NY).
13. Goodwin F.K., Murphy D.L., Bunney W.E. Lithium-carbonate treatment in depression and mania. A longitudinal double-blind study. Arch Gen Psychiatry. 21:1969;486-496.
14. Maggs R. Treatment of manic illness with lithium carbonate. Br J Psychiatry. 109:1963;56-65.
15. Schou M., Juel-Nielsen N., Stromgren E., et al. The treatment of manic psychoses by the administration of lithium salts. J Neurol Neurosurg Psychiatry. 17:1954;250-260.
16. Bowden C.L., Janicak P.G., Orsulak P., et al. Relation of serum valproate concentration to response in mania. Am J Psychiatry. 153:1996;765-770.
17. Bowden C.L., Brugger A.M., Swann A.C., et al. Efficacy of divalproex vs lithium and placebo in the treatment of mania. The Depakote Mania Study Group. [published erratum appears in JAMA 1994;271(23):1830] [see comments] JAMA. 271:1994;918-924.
18. Hagino O.R., Weller E.B., Weller R.A., et al. Untoward effects of lithium treatment in children aged four through six years. J Am Acad Child Adolesc Psychiatry. 34:1995;1584-1590.
19. Van Krevelen D.A., Van Voorst J.A. Lithium in the treatment of a cryptogenetic psychosis in a juvenile. Zeitschrift Fuer Kinderpsychiatrie. 26:1959;148-152.
20. DeLong G.R., Nieman G.W. Lithium-induced behavior changes in children with symptoms suggesting manic-depressive illness. Psychopharmacol Bull. 19:1983;258-265.
21. McKnew D.H., Cytryn L., Buchsbaum M.S., et al. Lithium in children of lithium-responding parents. Psychiatry Res. 4:1981;171-180.
22. DeLong G.R., Aldershof A.L. Long-term experience with lithium treatment in childhood: correlation with clinical diagnosis. J Am Acad Child Adolesc Psychiatry. 26:1987;389-394.
23. Gram L.F., Overo K.F., Andersen J., et al. Check to see if these outside brackets are right [Lu 5-003] in antidepressive therapy. A controlled clinical trial with simultaneous measurement of pharmacokinetic parameters. [review] Nord Psykiatr Tidsskr. 26:1972;361. [in Norwegian].
24. Brumback R.A., Weinberg W.A. Mania in childhood II. therapeutic trial of lithium carbonate and further description of manic-depressive illness in children. Am J Dis Child. 131:1977;1122-1126.
25. Carlson G., Strober M. Manic-depressive illness in early adolescence. A study of clinical and diagnostic characteristics in six cases. J Am Acad Child Adolesc Psychiatry. 17:1978;138-153.
26. Hassanyeh F., Davison K. Bipolar affective psychosis with onset before age 16 years: report of 10 cases. Br J Psychiatry. 137:1980;530-539.
27. Horowitz H.A. Lithium and the treatment of adolescent manic depressive illness. Dis Nerv Syst. 38:1977;480-483.
28. Strober M., Morrell W., Burroughs J., et al. A family study of bipolar I disorder in adolescence. Early onset of symptoms linked to increased familial loading and lithium resistance. J Affect Disord. 15:1988;255-268.
29. Campbell M., Adams P.B., Small A.M., et al. Lithium in hospitalized aggressive children with conduct disorder: a double-blind and placebo-controlled study. [published erratum appears in J Am Acad Child Adolesc Psychiatry 1995;34(5):694] J Am Acad Child Adolesc Psychiatry. 34:1995;445-453.
30. Campbell M., Fish B., Korein J., et al. Lithium and chlorpromazine: a controlled crossover study of hyperactive severely disturbed young children. J Autism Child Schizophr. 2:1972;234-263.
31. Campbell M., Small A.M., Green W.H., et al. Behavioral efficacy of haloperidol and lithium carbonate. A comparison in hospitalized aggressive children with conduct disorder. Arch Gen Psychiatry. 41:1984;650-656.
32. Siassi I. Lithium treatment of impulsive behavior in children. J Clin Psychiatry. 43:1982;482-484.
33. Cohn C.K. Lithium. Texas Medicine. 73:1977;73-75.
34. Joshi P., Capozzoli J.A., Coyle J.T. Effective management with lithium of a persistent, post-traumatic hypomania in a 10-year-old child. J Dev Behav Pediatr. 6:1985;352-354.
35. Geller B., Fox L.W., Fletcher M. Effect of tricyclic antidepressants on switching to mania and on the onset of bipolarity in depressed 6- to 12-year-olds. J Am Acad Child Adolesc Psychiatry. 32:1993;43-50.
36. American Psychiatric Association. Practice guideline for the treatment of patients with bipolar disorder. American Psychiatric Association. Am J Psychiatry. 151:1994;1-36.
37. Prien R.F., Potter W.Z. NIMH workshop report on treatment of bipolar disorder. Psychopharmacol Bull. 26:1990;409-427.
38. Geller B., Cooper T.B., Sun K., et al. Double-blind and placebo-controlled study of lithium for adolescent bipolar disorders with secondary substance dependency. J Am Acad Child Adolesc Psychiatry. 37:1998;171-178.
39. Hsu L.K., Starzynski J.M. Mania in adolescence. J Clin Psychiatry. 47:1986;596-599.
40. Young R.C., Biggs J.T., Ziegler V.E., et al. A rating scale for mania: reliability, validity and sensitivity. Br J Psychiatry. 133:1978;429-435.
41. Alessi N., Naylor M.W., Ghaziuddin M., et al. Update on lithium carbonate therapy in children and adolescents. [see comments] J Am Acad Child Adolesc Psychiatry. 33:1994;291-304.
42. Weller E.B., Weller R.A., Fristad M.A. Lithium dosage guide for prepubertal children: a preliminary report. J Am Acad Child Psychiatry. 25:1986;92-95.
43. Hagino O.R., Weller E.B., Weller R.A., et al. Comparison of lithium dosage methods for preschool- and early school-age children. J Am Acad Child Adolesc Psychiatry. 37:1998;60-65.
44. Geller B., Fetner H.H. Children's 24-hour serum lithium level after a single dose predicts initial dose and steady-state plasma level. J Clin Psychopharmacol. 9:1989;155.
45. Cooper T.B., Bergner P.E., Simpson G.M. The 24-hour serum lithium level as a prognosticator of dosage requirements. Am J Psychiatry. 130:1973;601-603.
46. Ahrens B., Grof P., Moller H.J., et al. Extended survival of patients on long-term lithium treatment. Can J Psychiatry. 40:1995;241-246.
47. Muller-Oerlinghausen B., Ahrens B., Grof E., et al. The effect of long-term lithium treatment on the mortality of patients with manic-depressive and schizoaffective illness. Acta Psychiatr Scand. 86:1992;218-222.
48. Muller-Oerlinghausen B., Wolf T., Ahrens B., et al. Mortality during initial and during later lithium treatment. A collaborative study by the International Group for the Study of Lithium-treated Patients. Acta Psychiatr Scand. 90:1994;295-297.
49. Schou M. Prophylactic lithium treatment of unipolar and bipolar manic-depressive illness. Psychopathology. 28:1995;81-85.
50. Schou M., Hansen H.E., Thomsen K., et al. Lithium treatment in Aarhus 2. Risk of renal failure and of intoxication. Pharmacopsychiatry. 22:1989;101-103.
51. Geller B., Sun K., Zimerman B., et al. Complex and rapid-cycling in bipolar children and adolescents: a preliminary study. J Affect Disord. 34:1995;259-268.
52. Himmelhoch J.M., Garfinkel M.E. Mixed mania: diagnosis and treatment. Psychopharmacol Bull. 22:1986;613.
53. Keller M.B., Lavori P.W., Coryell W., et al. Bipolar I: a five-year prospective follow-up. J Nerv Ment Dis. 181:1993;238-245.
54. Geller B., Luby J. Child and adolescent bipolar disorder: a review of the past 10 years. J Am Acad Child Adolesc Psychiatry. 36:1997;1168-1176.
55. Strober M., Schmidt-Lackner S., Freeman R., et al. Recovery and relapse in adolescents with bipolar affective illness: a five-year naturalistic, prospective follow-up. J Am Acad Child Adolesc Psychiatry. 34:1995;724-731.
56. Campbell M., Silva R.R., Kafantaris V., et al. Predictors of side effects associated with lithium administration in children. Psychopharmacol Bull. 27:1991;373-380.
57. Khandelwal S.K., Varma V.K., Srinivasa Murthy R. Renal function in children receiving long-term lithium prophylaxis. Am J Psychiatry. 141:1984;278-279.
58. Silva R.R., Campbell M., Golden R.R., et al. Side effects associated with lithium and placebo administration in aggressive children. Psychopharmacol Bull. 28:1992;319-326.
59. Rosenberg D.R., Holttum J., Gershon S. Textbook of pharmacotherapy for child and adolescent psychiatric disorders. 1994;Brunner/Mazel, New York (NY).
60. Birch N.J., Horsman A., Hullin R.P. Lithium, bone and body weight studies in long-term lithium-treated patients and in the rat. Neuropsychobiology. 8:1982;86-92.
61. Gelenberg A.J., Schoonover S.C. Bipolar disorder. Bassuk E.L., Schoonover S.C., Gelenberg A.J. The practitioner's guide to psychoactive drugs. 3rd edition:1991;91-124 Plenum, New York (NY).
62. Reisberg B., Gershon S. Side effects associated with lithium therapy. Arch Gen Psychiatry. 36:1979;879-887.
63. Hetmar O., Povlsen U.J., Ladefoged J., et al. Lithium: long-term effects on the kidney. A prospective follow-up study ten years after kidney biopsy. Br J Psychiatry. 158:1991;53-58.
64. Geller B., Fox L.W., Clark K.A. Rate and predictors of prepubertal bipolarity during follow-up of 6- to 12-year-old depressed children. [see comments] J Am Acad Child Adolesc Psychiatry. 33:1994;461-468.
65. Viesselman J.O., Yaylayan S., Weller E.B., et al. Antidysthymic drugs (antidepressants and antimanics). Werry J.S., Aman M.G. Practitioner's guide to psychoactive drugs for children and adolescents. 1993;239-268 Plenum, New York, NY.
66. Fristad M.A., Weller E.B., Weller R.A. The Mania Rating Scale: can it be used in children? A preliminary report. J Am Acad Child Alolesc Psychiatry. 31:1992;252-257.
67. Faedda G.L., Baldessarini R.J., Tohen M., et al. Episode sequence in bipolar disorder and response to lithium treatment. Am J Psychiatry. 148:1991;1237-1239.
68. Gelenberg A.J., Kane J.M., Keller M.B., et al. Comparison of standard and low serum levels of lithium for maintenance treatment of bipolar disorder. N Engl J Med. 321:1989;1489-1493.
69. Post R.M., Rubinow D.R., Uhde T.W., et al. Dysphoric mania. Clinical and biological correlates. Arch Gen Psychiatry. 46:1989;353-358.
70. Lena B. Lithium in child and adolescent psychiatry. Arch Gen Psychiatry. 36:1979;854-855.
71. Kutcher S.P., Marton P., Korenblum M. Adolescent bipolar illness and personality disorder. J Am Acad Child Adolesc Psychiatry. 29:1990;355-358.
72. Vitiello B., Behar D., Malone R., et al. Pharmacokinetics of lithium carbonate in children. J Clin Psychopharmacol. 8:1988;355-359.
73. De Santo N.G., Coppola S., Coscarella G., et al. Tubular function by lithium clearance, plasma amino acids and hormones following a meat meal in childhood. Ren Physiol Biochem. 14:1991;63-70.
74. McElroy S.L., Keck P.E. Jr., Pope H.G. Jr., et al. Valproate in the treatment of bipolar disorder: literature review and clinical guidelines. J Clin Psychopharmacol. 12:1992;42S-52S.
75. Pope H.G., McElroy S.L., Keck P.E., et al. Valproate in the treatment of acute mania. A placebo-controlled study. Arch Gen Psychiatry. 48:1991;62-68.
76. Strober M. The naturalistic prospective course of juvenile bipolar illness. Pittsburgh (PA); 1977.
77. Janicak P.G. The relevance of clinical pharmacokinetics and therapeutic drug monitoring: anticonvulsant mood stabilizers and antipsychotics. J Clin Psychiatry. 54:1993;35-41.
78. West S.A., Keck P.E., McElroy S.L., et al. Open trial of valproate in the treatment of adolescent mania. J Child Adolesc Psychopharmacol. 4:1994;263-267.
79. Kastner T., Friedman D.L. Verapamil and valproic acid treatment of prolonged mania. J Am Acad Child Adolesc Psychiatry. 31:1992;271-275.
80. Kastner T., Friedman D.L., Plummer A.T., et al. Valproic acid for the treatment of children with mental retardation and mood symptomatology. Pediatrics. 86:1990;467-472.
81. Whittier M.C., West S.A., Galli V.B., et al. Valproic acid for dysphoric mania in a mentally retarded adolescent. [letter] J Clin Psychiatry. 56:1995;590-591.
82. Messenheimer J., Mullens E.L., Giorgi L., et al. Safety review of adult clinical trial experience with lamotrigine. Drug Saf. 18:1998;281-296.
83. Papatheodorou G., Kutcher S.P. Divalproex sodium treatment in late adolescent and young adult acute mania. Psychopharmacol Bull. 29:1993;213-219.
84. Papatheodorou G., Kutcher S.P., Katic M., et al. The efficacy and safety of divalproex sodium in the treatment of acute mania in adolescents and young adults: an open clinical trial. J Clin Psychopharmacol. 15:1995;110-116.
85. Wagner J.G., Rocchini A.P., Vasiliades J. Prediction of steady-state verapamil plasma concentrations in children and adults. Clin Pharmacol Ther. 32:1982;172-181.
86. Walter G., Rey J.M., Mitchell P.B. Practitioner review: electroconvulsive therapy in adolescents. J Child Psychol Psychiatry. 40:1999;325-334.
87. West S.A., McElroy S.L., Strakowski S.M., et al. Attention deficit hyperactivity disorder in adolescent mania. Am J Psychiatry. 152:1995;271-273.
88. Donovan S.J., Susser E.S., Nunes E.V., et al. Divalproex treatment of disruptive adolescents: a report of 10 cases. J Clin Psychiatry. 58:1997;12-15.
89. Deltito J.A., Levitan J., Damore J., et al. Naturalistic experience with the use of divalproex sodium on an in-patient unit for adolescent psychiatric patients. Acta Psychiatr Scand. 97:1998;236-240.
90. Calabrese J.R., Fatemi S.H., Kujawa M., et al. Predictors of response to mood stabilizers. J Clin Psychopharmacol. 16:1996;24S-31S.
91. Pedley T.A., Scheuer M.L., Walczak T.S. Epilepsy. Rowland L.P. Merrits textbook of neurology. 9th edition:1995;845-869 Williams & Wilkins, Baltimore, MD.
92. Bryant A.E. III, Dreifuss F.E. Valproic acid hepatic fatalities III. U.S. experience since 1986. Neurology. 46:1996;465-469.
93. Silberstein S.D., Wilmore L.J. Divalproex sodium: migraine treatment and monitoring. Headache. 36:1996;239-242.
94. Isojarvi J.I., Laatikainen T.J., Pakarinen A.J., et al. Polycystic ovaries and hyperandrogenism in women taking valproate for epilepsy. N Engl J Med. 329:1993;1383-1388.
95. Isojarvi J.I., Laatikainen T.J., Knip M., et al. Obesity and endocrine disorders in women taking valproate for epilepsy. [see comments] Ann Neurol. 39:1996;579-584.
96. Isojarvi J.I., Rattya J., Myllyla V.V., et al. Valproate, lamotrigine, and insulin-mediated risks in women with epilepsy. Ann Neurol. 43:1998;446-451.
97. Ryan N.D., Bhatara V.S., Perel J.M. Mood stabilizers in children and adolescents. J Am Acad Child Adolesc Psychiatry. 38:1999;529-536.
98. Pleak R.R., Birmaher B., Gavrilescu A., et al. Mania and neuropsychiatric excitation following carbamazepine. J Am Acad Child Adolesc Psychiatry. 27:1988;500-503.
99. Okuma T., Kishimoto A., Inoue K., et al. Anti-manic and prophylactic effects of carbamazepine (Tegretol) on manic depressive psychosis. A preliminary report. Folia Psychiatr Neurol Jpn. 27:1973;283-297.
100. Post R.M., Ketter T.A., Denicoff K., et al. The place of anticonvulsant therapy in bipolar illness. Psychopharmacology (Berl). 128:1996;115-129.
101. Stuppaeck C., Barnas C., Miller C., et al. Carbamazepine in the prophylaxis of mood disorders. J Clin Psychopharmacol. 10:1990;39-42.
102. Solomon D.A., Keitner G.I., Ryan C.E., et al. Polypharmacy in bipolar I disorder. Psychopharmacol Bull. 32:1996;579-587.
103. Cueva J.E., Overall J.E., Small A.M., et al. Carbamazepine in aggressive children with conduct disorder: a double-blind and placebo-controlled study. J Am Acad Child Adolesc Psychiatry. 35:1996;480-490.
104. Evans R.W., Clay T.H., Gualtieri C.T. Carbamazepine in pediatric psychiatry. J Am Acad Child Adolesc Psychiatry. 26:1987;2-8.
105. Kafantaris V., Campbell M., Padron-Gayol M.V., et al. Carbamazepine in hospitalized aggressive conduct disorder children: an open pilot study. [published erratum appears in Psychopharmacol Bull 1992;28(3):220] Psychopharmacol Bull. 28:1992;193-199.
106. Hsu L.K. Lithium-resistant adolescent mania. J Am Acad Child Psychiatry. 25:1986;280-283.
107. Woolston J.L. Case study: carbamazepine treatment of juvenile-onset bipolar disorder. J Am Acad Child Adolesc Psychiatry. 38:1999;335-338.
108. Ballenger J.C. The use of anticonvulsants in manic-depressive illness. J Clin Psychiatry. 49:1988;21-25.
109. Post R.M., Uhde T.W., Roy-Byrne P.P., et al. Correlates of antimanic response to carbamazepine. Psychiatry Res. 21:1987;71-83.
110. Bhatara V.S., Carrera J. Medications for aggressiveness. J Am Acad Child Adolesc Psychiatry. 33:1994;282-283.
111. Carpenter R.O., Vining E.P.G. Antiepileptics (anticonvulsants). Werry J.S., Aman M.G. Practitioner's guide to psychoactive drugs for children and adolescents. 1993;321-346 Plenum, New York (NY).
112. Stores G., Williams P.L., Styles E., et al. Psychological effects of sodium valproate and carbamazepine in epilepsy. Arch Dis Child. 67:1992;1330-1337.
113. Calabrese J.R., Fatemi S.H., Woyshville M.J. Antidepressant effects of lamotrigine in rapid cycling bipolar disorder. [letter] [see comments] Am J Psychiatry. 153:1996;1236.
114. Fatemi S.H., Rapport D.J., Calabrese J.R., et al. Lamotrigine in rapid-cycling bipolar disorder. J Clin Psychiatry. 58:1997;522-527.
115. Fogelson D.L., Sternbach H. Lamotrigine treatment of refractory bipolar disorder. J Clin Psychiatry. 58:1997;271-273.
116. Chaffin J.J., Davis S.M. Suspected lamotrigine-induced toxic epidermal necrolysis. Ann Pharmacother. 31:1997;720-723.
117. Dooley J., Camfield P., Gordon K., et al. Lamotrigine-induced rash in children. Neurology. 46:1996;240-242.
118. Fogh K., Mai J. Toxic epidermal necrolysis after treatment with lamotrigine (Lamictal). Seizure. 6:1997;63-65.
119. Calabrese J.R., Suppes T., Bowden C.L., et al. A double-blind, placebo-controlled, prophylaxis study of lamotrigine in rapid-cycling bipolar disorder. Lamictal 614 Study Group. J Clin Psychiatry. 61:2000;841-850.
120. Mackay F.J., Wilton L.V., Pearce G.L., et al. Safety of long-term lamotrigine in epilepsy. Epilepsia. 38:1997;881-886.
121. Dichter M.A., Brodie M.J. New antiepileptic drugs. N Engl J Med. 334:1996;1583-1590.
122. Ryback R.S., Brodsky L., Munasifi F. Gabapentin in bipolar disorder. [letter] J Neuropsychiatry Clin Neurosci. 9:1997;301.
123. Schaffer C.B., Schaffer L.C. Gabapentin in the treatment of bipolar disorder. Am J Psychiatry. 154:1997;291-292.
124. Young L.T., Robb J.C., Patelis-Siotis I., et al. Acute treatment of bipolar depression with gabapentin. Biol Psychiatry. 42:1997;851-853.
125. Tallian K.B., Nahata M.C., Lo W., et al. Gabapentin associated with aggressive behavior in pediatric patients with seizures. Epilepsia. 37:1996;501-502.
126. Lee D.O., Steingard R.J., Cesena M., et al. Behavioral side effects of gabapentin in children. Epilepsia. 37:1996;87-90.
127. Garfinkel M, Garfinkel L, Himmelhoch J, et al. Lithium carbonate and carbamazepine: an effective treatment for adolescent manic or mixed bipolar patients. Proceedings of the Annual Meeting of the American Academy of Child and Adolescent Psychiatry, 1985. p. 41-2.
128. Soutullo C.A., Casuto L.S., Keck P.E. Jr. Gabapentin in the treatment of adolescent mania: a case report. J Child Adolesc Psychopharmacol. 8:1998;81-85.
129. Wolf S.M., Shinnar S., Kang H., et al. Gabapentin toxicity in children manifesting as behavioral changes. Epilepsia. 36:1995;1203-1205.
130. Ballenger J.C., Reus V.I., Post R.M. The "atypical" clinical picture of adolescent mania. Am J Psychiatry. 139:1982;602-606.
131. Joyce P.R. Age of onset in bipolar affective disorder and misdiagnosis as schizophrenia. Psychol Med. 14:1984;145-149.
132. Rosen L.N., Rosenthal N.E., Van Dusen P.H., et al. Age at onset and number of psychotic symptoms in bipolar I and schizoaffective disorder. Am J Psychiatry. 140:1983;1523-1524.
133. Goodnick P.J., Meltzer H.Y. Treatment of schizoaffective disorders. Schizophr Bull. 10:1984;30-48.
134. Janicak P.G., Newman R.H., Davis J.M. Advances in the treatment of mania and related disorders. Annals of Psychiatry. 22:1992;92-103.
135. Calabrese J.R., Kimmel S.E., Woyshville M.J., et al. Clozapine for treatment-refractory mania. Am J Psychiatry. 153:1996;759-764.
136. Kowatch R.A., Suppes T., Gilfillan S.K., et al. Clozapine treatment of children and adolescents with bipolar disorder and schizophrenia: a clinical case series. J Child Adolesc Psychopharmacol. 5:1995;241-253.
137. Fuchs D.C. Clozapine treatment of bipolar disorder in a young adolescent. J Am Acad Child Adolesc Psychiatry. 33:1994;1299-1302.
138. Killian J.G., Kerr K., Lawrence C., et al. Myocarditis and cardiomyopathy associated with clozapine. Lancet. 354:1999;1841-1845.
139. Arvanitis L.A., Miller B.G. Multiple fixed doses of "Seroquel" (quetiapine) in patients with acute exacerbation of schizophrenia: a comparison with haloperidol and placebo. The Seroquel Trial 13 Study Group. Biol Psychiatry. 42:1997;233-246.
140. Copolov D.L., Link C.G., Kowalcyk B. A multicentre, double-blind, randomized comparison of quetiapine (ICI 204,636, 'Seroquel') and haloperidol in schizophrenia. Psychol Med. 30:2000;95-105.
141. Peuskens J., Link C.G. A comparison of quetiapine and chlorpromazine in the treatment of schizophrenia. Acta Psychiatr Scand. 96:1997;265-273.
142. Small J.G., Hirsch S.R., Arvanitis L.A., et al. Quetiapine in patients with schizophrenia. A high- and low-dose double-blind comparison with placebo. Seroquel Study Group. Arch Gen Psychiatry. 54:1997;549-557.
143. Schaller J.L., Behar D. Quetiapine for refractory mania in a child. J Am Acad Child Adolesc Psychiatry. 38:1999;498-499.
144. Vieta E., Gasto C., Colom F., et al. Treatment of refractory rapid cycling bipolar disorder with risperidone. [letter] J Clin Psychopharmacol. 18:1998;172-174.
145. Ghaemi S.N., Sachs G.S., Baldassano C.F., et al. Acute treatment of bipolar disorder with adjunctive risperidone in outpatients. Can J Psychiatry. 42:1997;196-199.
146. Goodnick P.J. Risperidone treatment of refractory acute mania. [letter] J Clin Psychiatry. 56:1995;431-432.
147. McIntyre R., Young L.T., Hasey G., et al. Risperidone treatment of bipolar disorder. [letter] Can J Psychiatry. 42:1997;88-90.
148. Tohen M., Zarate C.A. Jr., Centorrino F., et al. Risperidone in the treatment of mania. J Clin Psychiatry. 57:1996;249-253.
149. Frazier J.A., Meyer M.C., Biederman J., et al. Risperidone treatment for juvenile bipolar disorder: a retrospective chart review. J Am Acad Child Adolesc Psychiatry. 38:1999;960-965.
150. Wozniak J., Biederman J., Kiely K., et al. Mania-like symptoms suggestive of childhood-onset bipolar disorder in clinically referred children. [see comments] J Am Acad Child Adolesc Psychiatry. 34:1995;867-876.
151. Frye M.A., Ketter T.A., Altshuler L.L., et al. Clozapine in bipolar disorder: treatment implications for other atypical antipsychotics. J Affect Disord. 48:1998;91-104.
152. Keck P.E. Jr., McElroy S.L. The new antipsychotics and their therapeutic potential. Psychiatr Ann. 27:1997;320-331.
153. Friedman L., Findling R.L., Kenny J.T., et al. An MRI study of adolescent patients with either schizophrenia or bipolar disorder as compared to healthy control subjects. [published erratum appears in Biol Psychiatry 1999;46(4):following 584] Biol Psychiatry. 46:1999;78-88.
154. Tollefson G.D., Beasley C.M., Tran P.V. Jr., et al. Olanzapine versus haloperidol in the treatment of schizophrenia and schizoaffective and schizophreniform disorders: results of an international collaborative trial. Am J Psychiatry. 154:1997;457-465.
155. McElroy S.L., Frye M., Denicoff K., et al. Olanzapine in treatment-resistant bipolar disorder. J Affect Disord. 49:1998;119-122.
156. Soutullo C.A., Sorter M.T., Foster K.D., et al. Olanzapine in the treatment of adolescent acute mania: a report of seven cases. J Affect Disord. 53:1999;279-283.
157. Chang K.D., Ketter T.A. Mood stabilizer augmentation with olanzapine in acutely manic children. J Child Adolesc Psychopharmacol. 10:2000;45-49.
158. Krishnamoorthy J., King B.H. Open-label olanzapine treatment in five preadolescent children. J Child Adolesc Psychopharmacol. 8:1998;107-113.
159. Black D.W., Winokur G., Nasrallah A. Treatment of mania: a naturalistic study of electroconvulsive therapy versus lithium in 438 patients. J Clin Psychiatry. 48:1987;132-139.
160. Welch C.A. Electroconvulsive therapy. Treatment of psychiatric disorders: a task force report of the American Psychiatric Association. 1989;1803-1813 The American Psychiatric Association, Washington, DC.
161. Small J.G., Klapper M.H., Kellams J.J., et al. Electroconvulsive treatment compared with lithium in the management of manic states. Arch Gen Psychiatry. 45:1988;727-732.
162. Bertagnoli M.W., Borchardt C.M. A review of ECT for children and adolescents. J Am Acad Child Adolesc Psychiatry. 29:1990;302-307.
163. Kutcher S., Robertson H.A. Electroconvulsive therapy in treatment-resistant bipolar youth. J Child Adolesc Psychopharmacol. 5:1995;167-175.
164. Davanzo P.A., Krah N., Kleiner J., et al. Nimodipine treatment of an adolescent with ultradian cycling bipolar affective illness. J Child Adolesc Psychopharmacol. 9:1999;51-61.
165. Stensby M.E. Nutritional properties of fish oils. World Rev Nutr Diet. 11:1969;46-105.
166. Sperling R.I., Benincaso A.I., Knoell C.T., et al. Dietary omega-3 polyunsaturated fatty acids inhibit phosphoinositide formation and chemotaxis in neutrophils. J Clin Invest. 91:1993;651-660.
167. Tappia P.S., Ladha S., Clark D.C., et al. The influence of membrane fluidity, TNF receptor binding, cAMP production and GTPase activity on macrophage cytokine production in rats fed a variety of fat diets. Mol Cell Biochem. 166:1997;135-143.