Intravenous iron and the risk of infection in end-stage renal disease patients

Seminars in Dialysis

Volumn 17, Issue 1, 2004, Pages 57-60

  Brewster, Ursula C ^a   Perazella, Mark A ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FERRIC GLUCONATE;

ADULT; ALLERGY; ANEMIA; BACTERIAL GROWTH; BACTERIAL INFECTION; BLOOD CULTURE; CASE REPORT; CATHETER; CLINICAL FEATURE; DRUG TOLERABILITY; DYSPNEA; EXERCISE TEST; FATIGUE; FEMALE; GLUCOSE BLOOD LEVEL; HEMODIALYSIS; HUMAN; IMMUNE RESPONSE; INFECTION RISK; IRON DEFICIENCY; IRON OVERLOAD; IRON THERAPY; KIDNEY FAILURE; NEPHROLOGY; REVIEW; SIDE EFFECT; STAPHYLOCOCCUS AUREUS;

EID: 1642277004     PISSN: 08940959     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1525-139x.2004.17115.x     Document Type: Review

References (35)

1. Collins AJ, Li S, St. Peter W: Death, hospitalization and economic associations among incident hemodialysis patients with hematocrit levels of 36% to 39%. J Am Soc Nephrol 12:2465-2473, 2001
2. NKF-K/DOQI clinical practice guidelines of anemia of chronic kidney disease: update 2000. Am J Kidney Dis 39:S182-S238, 2000
3. Fishbane S, Frei G, Maesaka J: Reduction in recombinant human erythropoietin doses by the use of chronic intravenous iron supplementation. Am J Kidney Dis 26:41-46, 1995
4. Sunder-Plassman G, Horl W: Comparative look at intravenous iron agents: pharmacology, efficacy, and safety of iron dextran, iron saccharate and ferric gluconate. Semin Dial 12:243-248, 1999
5. Faich G, Strobos J: Sodium ferric gluconate complex in sucrose: safer intravenous therapy than iron dextran. Am J Kidney Dis 33:464-470, 1999
6. Fishbane S: Safety in iron management. Am J Kidney Dis 41:S18-S26, 2003
7. Besarab A, Amin N, Ahsan M, Vogel S, Zazuwa G, Frinak S, Zazra J, Anandan J, Gupta A: Optimization of epoetin therapy with intravenous iron therapy in hemodialysis patients. J Am Soc Nephrol 11:530-538, 2000
8. Williams P, Griffiths E: Bacterial transferrin receptors - structure, function and contribution to virulence. Med Microbiol Immunol 181:301-322, 1992
9. Fishbane S: Review of issues relating to iron and infection. Am J Kidney Dis 34:S47-S52, 1999
10. Bullen JJ: The significance of iron in infection. Rev Infect Dis 3:1127-1138, 1981
11. Ward CG, Hammond J, Bullen J: Effect of iron compounds on antibacterial function of human polymorphs. Infect Immunol 15:723-730, 1986
12. Zaren A, Adriaansen H, Van Bommel E, Posthuma R, de Jong GT: Over-saturation of transferrin after intravenous ferric gluconate (Ferrlicit®) in haemodialysis patients. Nephrol Dial Transplant 11:820-824, 1996
13. Parkkinen J, vonBonsdorff L, Peltonen S, Gronhagen-Riska C, Rosenlof K: Catalytically active iron and bacterial growth in serum of haemodialysis patients after i.v. iron-saccharate administration. Nephrol Dial Transplant 15:1827-1834, 2000
14. Seligman P, Schleicher R: Comparison of methods used to measure serum iron in the presence of iron gluconate or iron dextran. Clin Chem 46:898-901, 1999
15. Mencacci A, Cenci E, Boelart J, Bucci P, Mosel P, d'Ostiani C, Bistoni F, Romani L: Iron overload alters innate and T helper cell responses to Candida albicans in mice. J Infect Dis 175:1467-1476, 1997
16. Vanholder R, Ringoir S: Infectious morbidity and defects of phagocytic function in end-stage renal disease: a review. J Am Soc Nephrol 3:1541-1554, 1993
17. vanAsbeck B, Marx J, Struyvenberg A, Verhoef J: Functional defects in phagocytic cells from patients with iron overload. J Infect 8:232-240, 1984
18. Patruta S, Edlinger R, Sunder-Plassmann G, Horl W: Neutrophil impairment associated with iron therapy in hemodialysis patients with functional iron deficiency. J Am Soc Nephrol 9:655-663, 1998
19. Deicher R, Ziai F, Cohen G, Mullner M, Horl W: High-dose parenteral iron sucrose depresses neutrophil intracellular killing capacity. Kidney Int 64:728-736, 2003
20. Ellison R, Giehl T: Killing of gram-negative bacteria by lactoferrin and lysozyme. J Clin Invest 88:1080-1091, 1991
21. Bonner C, Miller R, Arnold R: Bacteriacidal effect of lactoferrin on Legionella pneumophila. Infect Immunol 51:373-377, 1986
22. Seifert A, Von Herrath D, Schaefer K: Iron overload, but not treatment with deferoxamine favours the development of septicemia in patients on maintenance hemodialysis. Q J Med 65:1015-1024, 1987
23. Tieleman CL, Lenclud CM, Wens R, Collart FE, Dratwa M: Critical role of iron overload in the increased susceptibility of haemodialysis patients to bacterial infection. Beneficial effects of desferriozamine. Nephrol Dial Transplant 4:883-887, 1989
24. Boelaert JR, Daneels RF, Schurgers ML, Matthys EG, Gordts BZ, Van Landuyt HW: Iron overload in haemodialysis patients increases the risk of bacteraemia: a prospective study. Nephrol Dial Transplant 5:130-134, 1990
25. Hoen B, Kessler M, Hestin D, Mayeux D: Risk factors for bacterial infections in chronic hemodialysis adult patients: a multicentre prospective study. Nephrol Dial Transplant 10:377-381, 1995
26. Collins A, Ebben J, Ma J: Frequent IV iron dosing is associated with higher infectious deaths [abstract]. J Am Soc Nephrol 8:190A, 1997
27. Collins A, Ebben J, Ma J, Xia H: IV iron dosing patterns and mortality [abstract). J Am Soc Nephrol 9:205A, 1998
28. Feldman HI, Santanna J, Wensheng G, Furst H, Franklin E, Joffe M, Marcus S, Faich G: Iron administration and clinical outcomes in hemodialysis patients. J Am Soc Nephrol 13:734-744, 2002
29. Hoen B, Paul-Dauphin A, Hestin D, Kessler M: EPIBACDIAL: a multicenter prospective study of risk factors for bacteremia in chronic hemodialysis patients. J Am Soc Nephrol 9:869-876, 1998
30. Besarab A, Amin N, Ahsan M, Vogel S, Zazuwa G, Frinak S, Zazra J, Anandan J, Gupta A: Optimization of epoetin therapy with the intravenous iron therapy in hemodialysis patients. J Am Soc Nephrol 11:530-538, 2000
31. Briggs WA, Pederson MM, Mahajan SK, Sillix DH, Prasad AS, McDonald FD: Lymphocyte and granulocyte function inn zinc-treated and zinc-deficient hemodialysis patients. Kidney Int 21:827-832, 1982
32. Hubel E, Kiefer T, Weber J, Mettano T, Kuhlmann U: In vivo effect of 1,25-dihydroxyvitamin D3 on phagocyte function in hemodialysis patients. Kidney Int 40:927-933, 1991
33. Besarab A: Parenteral iron therapy: safety and efficacy. Semin Dial 12:237-242, 1999
34. Vanholder R, Van Biesen W, Ringoir S: Contributing factors to the inhibition of phagocytosis in hemodialyzed patients. Kidney Int 44:208-214, 1993
35. Vanholder R, Ringoir S, Dhondt A, Hakim R: Phagocytosis in uremic and hemodialysis patients: a prospective and cross sectional study. Kidney Int 39:320-327, 1991