메뉴 건너뛰기




Volumn 3, Issue SUPPL. 2, 2001, Pages

Effects of omapatrilat on pharmacodynamic biomarkers of neutral endopeptidase and angiotensin-converting enzyme activity in humans

Author keywords

[No Author keywords available]

Indexed keywords

ANTIHYPERTENSIVE AGENT; ATRIAL NATRIURETIC FACTOR; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; MEMBRANE METALLOENDOPEPTIDASE; OMAPATRILAT; PYRIDINE DERIVATIVE; THIAZEPINE DERIVATIVE; VASODILATOR AGENT;

EID: 1642270417     PISSN: 15226417     EISSN: 15343111     Source Type: Journal    
DOI: 10.1007/s11906-001-0103-x     Document Type: Article
Times cited : (8)

References (42)
  • 1
    • 0033011038 scopus 로고    scopus 로고
    • Vasopeptidase inhibition: A new concept in blood pressure management
    • Burnett JC: Vasopeptidase inhibition: a new concept in blood pressure management. J Hypertens 1999, 17(Suppl 1):S37-S43.
    • (1999) J Hypertens , vol.17 , Issue.SUPPL. 1
    • Burnett, J.C.1
  • 2
    • 0034241622 scopus 로고    scopus 로고
    • Vasopeptidase inhibition: A new direction in cardiovascular treatment
    • Asher JR, Naftilan AJ: Vasopeptidase inhibition: a new direction in cardiovascular treatment. Curr Hypertens Rep 2000, 2:384-391.
    • (2000) Curr Hypertens Rep , vol.2 , pp. 384-391
    • Asher, J.R.1    Naftilan, A.J.2
  • 3
    • 0024538318 scopus 로고
    • Neutral endopeptidase 24.11 (enkephalinase) and related regulators of peptide hormones
    • Erdös EG, Skidgel RA: Neutral endopeptidase 24.11 (enkephalinase) and related regulators of peptide hormones. FASEB J 1989, 3:145-151.
    • (1989) FASEB J , vol.3 , pp. 145-151
    • Erdös, E.G.1    Skidgel, R.A.2
  • 5
    • 0035007108 scopus 로고    scopus 로고
    • Pathways of angiotensin- (1-7) metabolism in the kidney
    • Chappell MC, Allred AJ, Ferrario CM: Pathways of angiotensin- (1-7) metabolism in the kidney. Nephrol Dial Transplant 2001, 16(Suppl):122-126.
    • (2001) Nephrol Dial Transplant , vol.16 , Issue.SUPPL. , pp. 122-126
    • Chappell, M.C.1    Allred, A.J.2    Ferrario, C.M.3
  • 6
    • 0026734608 scopus 로고
    • Candoxatril, a neutral endopeptidase inhibitor: Efficacy and tolerability in essential hypertension
    • Bevan EG, Connell JMC, Doyle J, et al.: Candoxatril, a neutral endopeptidase inhibitor: efficacy and tolerability in essential hypertension. J Hypertens 1992, 10:607-613.
    • (1992) J Hypertens , vol.10 , pp. 607-613
    • Bevan, E.G.1    Connell, J.M.C.2    Doyle, J.3
  • 8
    • 0003287217 scopus 로고
    • Combined atriopeptidase inhibition and angiotensin converting enzyme inhibition in hypertensive patients
    • Stergiou GS, Hannah JA, Bevan EG, et al.: Combined atriopeptidase inhibition and angiotensin converting enzyme inhibition in hypertensive patients. J Hypertens 1994, 12:1310-1311.
    • (1994) J Hypertens , vol.12 , pp. 1310-1311
    • Stergiou, G.S.1    Hannah, J.A.2    Bevan, E.G.3
  • 11
    • 0034130979 scopus 로고    scopus 로고
    • Vasopeptidase inhibition has potent effects on blood pressure and resistance arteries in stroke-prone spontaneously hypertensive rats
    • Intengan HD, Schiffrin EL: Vasopeptidase inhibition has potent effects on blood pressure and resistance arteries in stroke-prone spontaneously hypertensive rats. Hypertension 2000, 35:1221-1225. (Pubitemid 30413654)
    • (2000) Hypertension , vol.35 , Issue.6 , pp. 1221-1225
    • Intengan, H.D.1    Schiffrin, E.L.2
  • 12
    • 0035045775 scopus 로고    scopus 로고
    • Vasopeptidase inhibition exhibits endothelial protection in salt-induced hypertension
    • Quaschning T, d'Uscio LV, Shaw S, et al.: Vasopeptidase inhibition exhibits endothelial protection in salt-sensitive hypertension. Hypertension 2001, 37:1108-1113. (Pubitemid 32304012)
    • (2001) Hypertension , vol.37 , Issue.4 , pp. 1108-1113
    • Quaschning, T.1    D'Uscio, L.V.2    Shaw, S.3    Luscher, T.F.4
  • 13
    • 0000877531 scopus 로고    scopus 로고
    • Simultaneous inhibition of neutral endopeptidase and angiotensin covering enzyme by omapatrilat increased survival in heart failure hamsters greater than ACE inhibition [abstract]
    • Trippodo NC, Fox M, Monticello TM, et al.: Simultaneous inhibition of neutral endopeptidase and angiotensin covering enzyme by omapatrilat increased survival in heart failure hamsters greater than ACE inhibition [abstract]. Circulation 1998, 98:I-781.
    • (1998) Circulation , vol.98
    • Trippodo, N.C.1    Fox, M.2    Monticello, T.M.3
  • 14
    • 0001643315 scopus 로고    scopus 로고
    • Effects of BMS-186716, a new dual metalloprotease inhibitor, on pharmacodynamic markers of neutral endopeptidase (NEP) and angiotensin converting enzyme (ACE) activity in healthy men
    • Vesterqvist O, Manning JA, Uderman H, et al.: Effects of BMS- 186716, a new dual metalloprotease inhibitor, on pharmacodynamic markers of neutral endopeptidase (NEP) and angiotensin converting enzyme (ACE) activity in healthy men [abstract]. Clin Pharmacol Ther 1997, 61:230. (Pubitemid 127791618)
    • (1997) Clinical Pharmacology and Therapeutics , vol.61 , Issue.2 , pp. 230
    • Vesterqvist, O.1    Liao, W.2    Manning, J.A.3    Uderman, H.4    Delaney, C.5    Beierle, F.6    Swanson, B.N.7
  • 15
    • 0003007201 scopus 로고    scopus 로고
    • Pharmacodynamic effects of multiple doses of omapatrilat in healthy subjects
    • [abstract]
    • Vesterqvist O, Liao W, Manning JA, et al.: Pharmacodynamic effects of multiple doses of omapatrilat in healthy subjects [abstract]. Clin Pharmacol Ther 1999, 65:132.
    • (1999) Clin Pharmacol Ther , vol.65 , pp. 132
    • Vesterqvist, O.1    Liao, W.2    Manning, J.A.3
  • 16
    • 4244218180 scopus 로고    scopus 로고
    • Angiotensin-(1-7) and vasopeptidase inhibition [abstract]
    • Ferrario CM, Smith RD, Yunis C, et al.: Angiotensin-(1-7) and vasopeptidase inhibition [abstract]. Am J Hypertens 2000, 13:23A.
    • (2000) Am J Hypertens , vol.13
    • Ferrario, C.M.1    Smith, R.D.2    Yunis, C.3
  • 17
    • 0029144913 scopus 로고
    • Atrial natriuretic peptide and blood pressure in a population-based sample
    • Flickinger AL, Burnett JC, Turner ST: Atrial natriuretic peptide and blood pressure in a population-based sample. Mayo Clin Proc 1995, 70:932-938.
    • (1995) Mayo Clin Proc , vol.70 , pp. 932-938
    • Flickinger, A.L.1    Burnett, J.C.2    Turner, S.T.3
  • 18
    • 0028568254 scopus 로고
    • Atrial natriuretic peptide and its potential role in pharmacotherapy
    • Deutch A, Frishman WH, Sukenik D, et al.: Atrial natriuretic peptide and its potential role in pharmacotherapy. J Clin Pharmacol 1994, 34:1133-1147.
    • (1994) J Clin Pharmacol , vol.34 , pp. 1133-1147
    • Deutch, A.1    Frishman, W.H.2    Sukenik, D.3
  • 19
    • 0032757411 scopus 로고    scopus 로고
    • Comparison of the short-term effects of candoxatril, an orally active neutral endopeptidase inhibitor, and frusemide in the treatment of patients with chronic heart failure
    • Northridge DB, Newby DE, Rooney E, et al.: Comparison of the short-term effects of candoxatril, an orally active neutral endopeptidase inhibitor, and frusemide in the treatment of patients with chronic heart failure. Am Heart J 1999, 138:1149-1157.
    • (1999) Am Heart J , vol.138 , pp. 1149-1157
    • Northridge, D.B.1    Newby, D.E.2    Rooney, E.3
  • 20
    • 0022903325 scopus 로고
    • Metabolic clearance rate and plasma half life of alpha-human atrial natriuretic peptide in man
    • DOI 10.1016/0024-3205(86)90137-2
    • Yandle TG, Richards AM, Nicholls MG, et al.: Metabolic clearance rate and plasma half life of alpha-human atrial natriuretic peptide in man. Life Sci 1986, 38:1827-1833. (Pubitemid 16068742)
    • (1986) Life Sciences , vol.38 , Issue.20 , pp. 1827-1833
    • Yandle, T.G.1    Richards, A.M.2    Nicholls, M.G.3
  • 21
    • 0023126676 scopus 로고
    • Relationship of increased plasma atrial natriuretic factor and renal sodium handling during immersion-induced central hypervolemia in normal humans
    • Epstein M, Loutzenhiser R, Friedland E, et al.: Relationship of increased plasma atrial natriuretic factor and renal sodium handling during immersion-induced central hypervolemia in normal humans. J Clin Invest 1987, 79:738-745. (Pubitemid 17050897)
    • (1987) Journal of Clinical Investigation , vol.79 , Issue.3 , pp. 738-745
    • Epstein, M.1    Loutzenhiser, R.2    Friedland, E.3
  • 22
    • 0022499232 scopus 로고
    • Effects of posture on plasma immunoreactive atrial natriuretic peptide concentrations in man
    • Solomon LR, Atherton JC, Bobinski H, et al.: Effect of posture on plasma immunoreactive atrial natriuretic peptide concentrations in man. Clin Sci 1986, 71:299-305. (Pubitemid 16058740)
    • (1986) Clinical Science , vol.73 , Issue.3 , pp. 299-305
    • Solomon, L.R.1    Atherton, J.C.2    Bobinski, H.3    Green, R.4
  • 23
    • 4243805329 scopus 로고    scopus 로고
    • Omapatrilat or lisinopril in salt-sensitive hypertensives [abstract]
    • Campese VM, Ferrario CM, Ruddy MC, et al.: Omapatrilat or lisinopril in salt-sensitive hypertensives [abstract]. Am J Hypertens 2000, 13:A15.
    • (2000) Am J Hypertens , vol.13
    • Campese, V.M.1    Ferrario, C.M.2    Ruddy, M.C.3
  • 24
    • 0033862042 scopus 로고    scopus 로고
    • The clinical, cardiac, renal, arterial and neurohormonal effects of omapatrilat, a vasopeptidase inhibitor, in patients with chronic heart failure
    • DOI 10.1016/S0735-1097(00)00741-5, PII S0735109700007415
    • McClean DR, Ikram H, Garlick AH, et al.: The clinical, cardiac, renal, arterial and neurohormonal effects of omapatrilat, a vasopeptidase inhibitor, in patient with chronic heart failure. J Am Coll Cardiol 2000, 36:479-486. (Pubitemid 30624011)
    • (2000) Journal of the American College of Cardiology , vol.36 , Issue.2 , pp. 479-486
    • McClean, D.R.1    Ikram, H.2    Garlick, A.H.3    Richards, A.M.4    Nicholls, M.G.5    Crozier, I.G.6
  • 26
    • 0026481029 scopus 로고
    • Effect of inhibition of endopeptidase 24.11 on responses to angiotensin II in human volunteers
    • Richards AM, Wittert G, Espiner EA, et al.: Effect of inhibition of endopeptidase 24.11 on responses to angiotensin II in human volunteers. Circ Res 1992, 71:1501-1507.
    • (1992) Circ Res , vol.71 , pp. 1501-1507
    • Richards, A.M.1    Wittert, G.2    Espiner, E.A.3
  • 27
    • 0028931280 scopus 로고
    • Natriuretic responses to neutral endopeptidase inhibition is blunted by enalapril in healthy men
    • Motwani JG, Lang CC, Cramb G, et al.: Natriuretic responses to neutral endopeptidase inhibition is blunted by enalapril in healthy men. Hypertension 1995, 25:637-642.
    • (1995) Hypertension , vol.25 , pp. 637-642
    • Motwani, J.G.1    Lang, C.C.2    Cramb, G.3
  • 28
    • 0032971240 scopus 로고    scopus 로고
    • Pharmacodynamic effects of dual neutral endopeptidase - Angiotensin- converting enzyme inhibition versus angiotensin-converting enzyme inhibition in humans
    • Massien C, Azizi M, Guyene TT, et al.: Pharmacodynamic effects of dual neutral endopeptidase-angiotensin-converting enzyme inhibition versus angiotensin-converting enzyme inhibition in humans. Clin Pharmacol Ther 1999, 65:448-459. (Pubitemid 29196549)
    • (1999) Clinical Pharmacology and Therapeutics , vol.65 , Issue.4 , pp. 448-459
    • Massien, C.1    Azizi, M.2    Guyene, T.-T.3    Vesterqvist, O.4    Mangold, B.5    Menard, J.6
  • 30
    • 0028920050 scopus 로고
    • Renal localization and actions of adrenomedullin: A natriuretic peptide
    • Jougasaki M, Wei C, Aarhus L, et al.: Renal localization and actions of adrenomedullin: a natriuretic peptide. Am J Physiol 1995, 268:F657-F663.
    • (1995) Am J Physiol , vol.268
    • Jougasaki, M.1    Wei, C.2    Aarhus, L.3
  • 32
    • 0029081173 scopus 로고
    • Elevation of circulating and ventricular adrenomedullin in human congestive heart failure
    • Jougasaki M, Wei C, McKinley L, et al.: Elevation of circulating and ventricular adrenomedullin in human congestive heart failure. Circulation 1995, 92:286-289.
    • (1995) Circulation , vol.92 , pp. 286-289
    • Jougasaki, M.1    Wei, C.2    McKinley, L.3
  • 33
    • 0031689073 scopus 로고    scopus 로고
    • Neutral endopeptidase inhibition potentiates the natriuretic actions of adrenomedullin
    • Lisy O, Jougasaki M, Schirger J, et al.: Neutral endopeptidase inhibition potentiates the natriuretic actions of adrenomedullin. Am J Physiol 1998, 275:F410-F414.
    • (1998) Am J Physiol , vol.275
    • Lisy, O.1    Jougasaki, M.2    Schirger, J.3
  • 34
    • 0001061909 scopus 로고    scopus 로고
    • Omapatrilat increases plasma concentrations of adrenomedullin in salt-sensitive hypertensives [abstract]
    • Vesterqvist O, Campese VM, Liao W, et al.: Omapatrilat increases plasma concentrations of adrenomedullin in salt-sensitive hypertensives [abstract]. Am J Hypertens 2000, 13:125A.
    • (2000) Am J Hypertens , vol.13
    • Vesterqvist, O.1    Campese, V.M.2    Liao, W.3
  • 35
    • 0032216598 scopus 로고    scopus 로고
    • Angiotensin-(1-7) and antihypertensive mechanisms
    • Ferrario CM: Angiotensin-(1-7) and antihypertensive mechanisms. J Nephrol 1998, 11:278-283. (Pubitemid 29071216)
    • (1998) Journal of Nephrology , vol.11 , Issue.6 , pp. 278-283
    • Ferrario, C.M.1
  • 36
    • 0001410628 scopus 로고    scopus 로고
    • Marked elevation in plasma renin activity [PRA] in response to omapatrilat in healthy, normotensive males [abstract]
    • Liao W, Delaney CL, Manning JA, et al.: Marked elevation in plasma renin activity [PRA] in response to omapatrilat in healthy, normotensive males [abstract]. Circulation 1998, 98:3802.
    • (1998) Circulation , vol.98 , pp. 3802
    • Liao, W.1    Delaney, C.L.2    Manning, J.A.3
  • 37
    • 0000720811 scopus 로고    scopus 로고
    • The safety and 24-hour antihypertensive efficacy of the vasopeptidase inhibitor omapatrilat: A pilot study [abstract]
    • Ruddy M, Guthrie R, Papademetriou V: The safety and 24-hour antihypertensive efficacy of the vasopeptidase inhibitor omapatrilat: a pilot study [abstract]. Am J Hypertens 1999, 12:125A.
    • (1999) Am J Hypertens , vol.12
    • Ruddy, M.1    Guthrie, R.2    Papademetriou, V.3
  • 38
    • 0000720810 scopus 로고    scopus 로고
    • Efficacy and safety of omapatrilat, a vasopeptidase inhibitor [abstract]
    • Zusman R, Atlas S, Kochar M, et al.: Efficacy and safety of omapatrilat, a vasopeptidase inhibitor [abstract]. Am J Hypertens 1999, 12:125A.
    • (1999) Am J Hypertens , vol.12
    • Zusman, R.1    Atlas, S.2    Kochar, M.3
  • 39
    • 0032712735 scopus 로고    scopus 로고
    • Emerging treatments for hypertension: Potential role for vasopeptidase inhibition
    • Weber M: Emerging treatments for hypertension: Potential role for vasopeptidase inhibition. Am J Hypertens 1999, 12:139S-147S.
    • (1999) Am J Hypertens , vol.12
    • Weber, M.1
  • 40
    • 0000521680 scopus 로고    scopus 로고
    • Omapatrilat, a novel vasopeptidase inhibitor, reduces blood pressure in normotensive subjects [abstract]
    • Liao W, Delaney CL, Beierle FA, et al.: Omapatrilat, a novel vasopeptidase inhibitor, reduces blood pressure in normotensive subjects [abstract]. J Am Coll Cardiol 1999, 33:309A.
    • (1999) J Am Coll Cardiol , vol.33
    • Liao, W.1    Delaney, C.L.2    Beierle, F.A.3
  • 41
    • 0002136038 scopus 로고    scopus 로고
    • The neurohumoral hypothesis and the treatment of heart failure
    • Rouleau JL: The neurohumoral hypothesis and the treatment of heart failure. Can J Cardiol 1996, 12(Suppl F):3-8.
    • (1996) Can J Cardiol , vol.12 , Issue.SUPPL. F , pp. 3-8
    • Rouleau, J.L.1
  • 42
    • 0034686963 scopus 로고    scopus 로고
    • Comparison of vasopeptidase inhibitor, omapatrilat, and lisinopril on exercise tolerance and morbidity in patients with heart failure: IMPRESS randomised trial
    • Rouleau JL, Pfeffer MA, Stewart DJ, et al.: Comparison of vasopeptidase inhibitor, omapatrilat, and lisinopril on exercise tolerance and morbidity in patients with heart failure: IMPRESS randomised trial. Lancet 2000, 356:615-620. (Pubitemid 30627587)
    • (2000) Lancet , vol.356 , Issue.9230 , pp. 615-620
    • Rouleau, J.L.1    Pfeffer, M.A.2    Stewart, D.J.3    Isaac, D.4    Sestier, F.5    Kerut, E.K.6    Porter, C.B.7    Proulx, G.8    Qian, C.9    Block, A.J.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.