Histamine regulates the MAPK pathway via the H 2 receptor in PANC-1 human cells

Inflammation Research

Volumn 53, Issue SUPPL. 1, 2004, Pages

  Cricco, G ^a   Martin G ^a   Medina, V ^a   Nunez M ^a   Gutierrez A ^a   Cocca, C ^a   Bergoc, R ^a,b   Rivera, E ^a,b  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b Argentina   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; DIMAPRIT; FORSKOLIN; HISTAMINE; HISTAMINE H1 RECEPTOR; HISTAMINE H2 RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PHOSPHOLIPASE C INHIBITOR;

APOPTOSIS; CARCINOMA CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONFERENCE PAPER; CONTROLLED STUDY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; PANCREAS CARCINOMA; RECEPTOR UPREGULATION;

CELL DIVISION; CELLS, CULTURED; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME ACTIVATION; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HISTAMINE; HUMANS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHATIDYLINOSITOLS; PHOSPHOLIPASE C; RECEPTORS, HISTAMINE H2;

EID: 1642269118     PISSN: 10233830     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00011-003-0331-4     Document Type: Conference Paper

References (6)

1. Cricco G, Martín G, Labombarda F, Cocca C, Bergoc R, Rivera E. Human pancreatic carcinoma cell line PANC-1 and the role of histamine in growth regulation. Inflamm Res 2000; 49: S68-9.
2. Martín G, Cricco G, Darvas Z, Croci M, Núñez M, Bergoc R et al. Histamine inhibits proliferation of a pancreatic carcinoma cell line without inducing apoptosis significantly. Inflamm Res 2002; 51: S67-8.
3. 1 receptor in DDT(1)MF-2 cells. Br J Pharmacol 2001; 133: 1378-86.
4. Liebmann C. Regulation of MAP kinase activity by peptide receptor signalling pathway: paradigms of multiplicity. Cell Signal 2001; 13: 777-85.
5. Ding X, Adrian T. MEK/ERK mediated proliferation is negatively regulated by p38 MAP Kinase in the human pancreatic cancer cell line, PANC-1. Biochem Biophys Res Commun 2001; 282: 447-53.
6. Murphy L, Cluck M, Lovas S, Otvos F, Murphy R, Schally A et al. Pancreatic cancer cells require an EGF receptor-mediated autocrine pathway for proliferation in serum-free conditions. Br J Cancer 2001; 84: 926-35.