Dose-dependent promoting effect of dextran sodium sulfate on mouse colon carcinogenesis initiated with azoxymethane

Histology and Histopathology

Volumn 20, Issue 2, 2005, Pages 483-492

  Suzuki, Rikako ^a,b   Kohno, H ^a   Sugie, S ^a   Tanaka, T ^a  

^a KANAZAWA MEDICAL UNIVERSITY   (Japan)

^b JAPAN SOCIETY FOR THE PROMOTION OF SCIENCE   (Japan)

Author keywords

AOM; Dose dependency; DSS; Mouse colon carcinogenesis; Promotion

Indexed keywords

3 NITROTYROSINE; AZOXYMETHANE; DEXTRAN SULFATE; DRINKING WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLITIS; COLON ADENOCARCINOMA; COLON ADENOMA; COLON CARCINOGENESIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE SEVERITY; DYSPLASIA; FISHER EXACT TEST; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INCIDENCE; MALE; MOUSE; NITROSATION; NONHUMAN; OXIDATIVE STRESS; STUDENT T TEST;

ANIMALS; AZOXYMETHANE; CARCINOGENS; COCARCINOGENESIS; COLITIS; COLONIC DISEASES; COLONIC NEOPLASMS; DEXTRAN SULFATE; DOSE-RESPONSE RELATIONSHIP, DRUG; INTESTINAL MUCOSA; MALE; MICE; MICE, INBRED ICR; TYROSINE; ULCER;

ANIMALIA; MARTES PENNANTI;

EID: 16344394046     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Babbs C.F. (1992). Oxygen radicals in ulcerative colitis. Free Rad. Biol. Med. 13, 169-181.
2. Buffinton G.D. and Doe W.F. (1995). Depleted mucosal antioxidant defenses in inflammatory bowel disease. Free Rad. Biol. Med. 19, 911-918.
3. Cooper H.S., Murthy S., Kido K., Yoshitake H. and Flanigan A. (2000). Dysplasia and cancer in the dextran sulfate sodium mouse colitis model. Relevance to colitis-associated neoplasia in the human: a study of histopathology, β-catenin and p53 expression and the role of inflammation. Carcinogenesis 21, 757-768.
4. Cooper H.S., Murthy S.N., Shah R.S. and Sedergran D.J. (1993). Clinicopathologic study of dextran sulfate sodium experimental murine colitis. Lab. Invest 69, 238-249.
5. Devroede G.J., Taylor W.F., Sauer W.G., Jackman R.J. and Stickler G.B. (1971). Cancer risk and life expectancy of children with ulcerative colitis. N. Engl. J. Med. 285, 17-21.
6. Eaden J.A., Abrams K.R. and Mayberry J.F. (2001). The risk of colorectal cancer in ulcerative colitis: a meta-analysis. Gut 48, 526-535.
7. Egger B., Bajaj-Elliott M., MacDonald T.T., Inglin R., Eysselein V.E. and Buchler M.W. (2000). Characterisation of acute murine dextran sodium sulphate colitis: cytokine profile and dose dependency. Digestion 62, 240-248.
8. Greenstein A.J., Sachar D.B., Smith H., Pucillo A., Papatestas A.E., Kreel I., Geller S.A., Janowitz H.D. and Aufses A.H.J. (1979). Cancer in universal and left-sided ulcerative colitis: factors determining risk. Gastroenterology 77, 290-294.
9. Grisham M.B. (1994). Oxidants and free radicals in inflammatory bowel disease. Lancet 344, 859-861.
10. Halliwell B. (1997). What nitrates tyrosine? Is nitrotyrosine specific as a biomarker of peroxynitrite formation in vivo? FEBS Lett. 411, 157-160.
11. Hardy R.G., Meltzer S.J. and Jankowski J.A. (2000). ABC of colorectal cancer. Molecular basis for risk factors. Br. Med. J. 321, 886-889.
12. Kewenter J., Ahlman H. and Hulten L. (1978). Cancer risk in extensive ulcerative colitis. Ann. Surg. 188, 824-848.
13. Kimura H., Hokari R., Miura S., Shigematsu T., Hirokawa M., Akiba Y., Kurose I., Higuchi H., Fujimori H., Tsuzuki Y., Serizawa H. and Ishii H. (1998). Increased expression of an inducible isoform of nitric oxide synthase and the formation of peroxynitrite in colonic mucosa of patients with active ulcerative colitis. Gut 42, 180-187.
14. Kimura H., Miura S., Shigematsu T., Ohkubo N., Tsuzuki Y., Kurose I., Higuchi H., Akiba Y., Hokari R., Hirokawa M., Serizawa H. and Ishii H. (1997). Increased nitric oxide production and inducible nitric oxide synthase activity in colonic mucosa of patients with active ulcerative colitis and Crohn's disease. Dig. Dis. Sci. 42, 1047-1054.
15. Kitajima S., Takuma S. and Morimoto M. (1999). Changes in colonic mucosal permeability in mouse colitis induced with dextran sulfate sodium. Exp. Anim. 48, 137-143.
16. Kullmann F., Messmann H., Alt M., Gross V., Bocker T., Scholmerich J. and Ruschoff J. (2001). Clinical and histopathological features of dextran sulfate sodium induced acute and chronic colitis associated with dysplasia in rats. Int. J. Colorectal Dis. 16, 238-246.
17. Lih-Brody L., Powell S.R., Collier K.P., Reddy G., Cerchia R., Kahn E., Weissman G.S., Katz S., Floyd R.A., McKinley M.J., Fisher S.E. and Mullin G.E. (1996). Increased oxidative stress and decreased antioxidant defenses in mucosa of inflammatory bowel disease. Dig. Dis. Sci. 41, 2078-2086.
18. Lundberg J.O., Hellstrom P.M., Lundberg J.M. and Alving K. (1994). Greatly increased luminal nitric oxide in ulcerative colitis. Lancet 344, 1673-1674.
19. Maekawa A., Onodera H., Ogasawara H., Matsushima Y., Mitsumori K. and Hayashi Y. (1992). Threshold dose dependence in phenobarbital promotion of rat hepatocarcinogenesis initiated by diethylnitrosamine. Carcinogenesis 13, 501-503.
20. Mitamura T., Sakamoto S., Sassa S., Suzuiki S., Kudo H. and Okayasu I. (2002). The more an ulcerative colitis is repeated, the more the risk of colorectal carcinogenesis is increased in mice. Anticancer Res. 22, 3955-3961.
21. Okayasu I., Hatakeyama S., Yamada M., Ohkusa T., Inagaki Y. and Nakaya R. (1990). A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice. Gastroenterology 98, 694-702.
22. Okayasu I., Yamada M., Mikami T., Yoshida T., Kanno J. and Ohkusa T. (2002). Dysplasia and carcinoma development in a repeated dextran sulfate sodium-induced colitis model. J. Gastroenterol. Hepatol. 17, 1078-1083.
23. Oudkerk Pool M., Bouma G., Visser J.J., Kolkman J.J., Tran D.D., Meuwissen S.G.M. and Pena A.S. (1995). Serum nitrate levels in ulcerative colitis and Crohn's disease. Scand. J. Gastroenterol. 30, 784-788.
24. Pascal R.R. (1994). Dysplasia and early carcinoma in inflammatory bowel disease and colorectal adenomas. Hum. Pathol. 25, 1160-1171.
25. Pereira M.A., Herren-Freund S.L. and Long R.E. (1986). Dose-response relationship of phenobarbital promotion of diethylnitrosamine initiated tumors in rat liver. Cancer Lett. 32, 305-311.
26. Rachmilewitz D., Stamler J.S., Karmeli F., Mullins M.E., Singel D.J., Loscalzo J., Xavier R.J. and Podolsky D.K. (1993). Peroxynitrite-induced rat colitis - a new model of colonic inflammation. Gastroenterology 105, 1681-1688.
27. Reddy B.S. and Maeura Y. (1984). Tumor promotion by dietary fat in azoxymethane-induced colon carcinogenesis in female F344 rats: influence of amount and source of dietary fat. J. Natl. Cancer Inst. 72, 745-750.
28. Riddell R.H., Goldman H., Ransohoff D.F., Appelman H.D., Fenoglio C.M., Haggitt R.C., Ahren C., Correa P., Hamilton S.R. and Morson B.C. (1983). Dysplasia in inflammatory bowel disease: standardized classification with provisional clinical applications. Hum. Pathol. 14, 931-968.
29. Shimizu T., Suzuki M., Fujimura J., Hisada K., Yoshikazu O., Obinata K. and Yamashiro Y. (2003). The relationship between the concentration of dextran sodium sulfate and the degree of induced experimental colitis in weanling rats. J. Pediatr. Gastroenterol. Nutr. 37, 481-486.
30. Singer I.I., Kawka D.W., Scott S., Weidner J.R., Mumford R.A., Riehl T.E. and Stenson W.F. (1996). Expression of inducible nitric oxide synthase and nitrotyrosine in colonic epithelium in inflammatory bowel disease. Gastroenterology 111, 871-885.
31. Suzuki R., Kohno H., Sugie S. and Tanaka T. (2004). Sequential observations on the occurrence of preneoplastic and neoplastic lesions in mouse colon treated with azoxymethane and dextran sodium sulfate. Cancer Sci. 95, 721-727.
32. Takesue F., Korenaga D., Yao T., Kabashima A. and Sugimachi K. (2001). Development of colonic neoplasms and expressions of p53 and p21 proteins in experimental colitis of mice induced by dextran sulfate sodium. J. Exp. Clin. Cancer Res. 20, 413-418.
33. Tamaru T., Kobayashi H., Kishimoto S., Kajiyama G., Shimamoto F. and Brown W.R. (1993). Histochemical study of colonic cancer in experimental colitis of rats. Dig. Dis. Sci. 38, 529-537.
34. Tanaka T., Kohno H., Suzuki R., Yamada Y., Sugie S. and Mori H. (2003). A novel inflammation-related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate. Cancer Sci. 94, 965-973.
35. Tanaka T., Kohno H., Yoshitani S., Takashima S., Okumura A., Murakami A. and Hosokawa M. (2001). Ligands for peroxisome proliferator-activated receptors a and g inhibit chemically induced colitis and formation of aberrant crypt foci in rats. Cancer Res. 61.
36. van Hogezand R.A., Eichhorn R.F., Choudry A., Veenendaal R.A. and Lamers C.B. (2002). Malignancies in inflammatory bowel disease: fact or fiction? Scand. J. Gastroenterol. Suppl 236, 48-53.
37. Ward J.M. (1974). Morphogenesis of chemically induced neoplasms of the colon and small intestine in rats. Lab. Invest. 30, 505-513.
38. Yamada M., Ohkusa T. and Okayasu I. (1992). Occurrence of dysplasia and adenocarcinoma after experimental chronic ulcerative colitis in hamsters induced by dextran sulphate sodium. Gut 33, 1521-1527.
39. Zingarelli B., Szabo C. and Salzman A.L. (1999). Reduced oxidative and nitrosative damage in murine experimental colitis in the absence of inducible nitric oxide synthase. Gut 45, 199-209.