Comparison of bovine leukemia virus (BLV) and CMV promoter-driven reporter gene expression in BLV-infected and non-infected cells

Genetic Vaccines and Therapy

Volumn 2, Issue , 2004, Pages

  Harms, Jerome S ^a   Eakle, Kurt A ^b   Kuo, Lillian S ^a   Bremel, Robert D ^c   Splitter, Gary A ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b Gala Design   (United States)

^c IoGenetics LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LUCIFERASE; TRICHOSTATIN A;

ARTICLE; B LYMPHOCYTE; BOVINE LEUKEMIA VIRUS; CELL LINE; CYTOMEGALOVIRUS; ENZYME ASSAY; EXPRESSION VECTOR; GENE ACTIVITY; GENE EXPRESSION; GENETIC TRANSDUCTION; LONG TERMINAL REPEAT; MAMMAL; NONHUMAN; PROMOTER REGION; REPORTER GENE; VIRUS INFECTION;

EID: 16344389514     PISSN: 14790556     EISSN: None     Source Type: Journal    
DOI: 10.1186/1479-0556-2-11     Document Type: Article

References (34)

1. Fitzsimons HL, Bland RJ, During MJ: Promoters and regulatory elements that improve adeno-associated virus transgene expression in the brain. Methods 2002, 28:227-236.
2. Xu ZL, Mizuguchi H, Mayumi T, Hayakawa T: Regulated gene expression from adenovirus vectors: A systematic comparison of various inducible systems. Gene 2003, 309:145-151.
3. Derse D, Casey JW: Two elements in the bovine leukemia virus long terminal repeat that regulate gene expression. Science 1986, 231:1437-1440.
4. Katoh I, Yoshinaka Y, Ikawa Y: Bovine leukemia virus transactivatorp38tax activates heterologous promoters with a common sequence known as a cAMP-responsive element or the binding site of a cellular transcription factor ATF. The Embo Journal 1989, 8: 97-503.
5. Derse D: Bovine leukemia virus transcription is controlled by a virus-encoded trans-acting factor and by cis-acting response elements. Journal of Virology 1987, 61:2462-2471.
6. Merezak C, Pierreux C, Adam E, Lemaigre F, Rousseau GG, Calomme C, Van Lint C, Christophe D, Kerkhofs P, Burny A, et al.: Suboptimal enhancer sequences are required for efficient bovine leukemia virus propagation in vivo: Implications for viral latency. Journal of Virology 2001, 75:6977-6988.
7. Adam E, Kerkhofs P, Mammerickx M, Burny A, Kettman R, Willems L: The CREB, ATF-1, and ATF-2 transcription factors from bovine leukemia virus-infected B lymphocytes activate viral expression. J Virol 1996, 70:1990-1999.
8. Adam E, Kerkhofs P, Mammerickx M, Kettmann R, Burny A, Droogmans L, Willems L: Involvement of the cyclic AMP-responsive element binding protein in bovine leukemia virus expression in vivo. J Virol 1994, 68:5845-5853.
9. Willems L, Grimonpont C, Heremans H, Rebeyrotte N, Chen G, Portetelle D, Burny A, Kettmann R: Mutations in the bovine leukemia virus Tax protein can abrogate the long terminal repeat-directed transactivating activity without concomitant loss of transforming potential. Proc Natl Acad Sci U S A 1992, 89:3957-3961.
10. Unk I, Kiss-Toth E, Boros I: Transcription factor AP-4 participates in activation of bovine leukemia virus long terminal repeat by p34 Tax. Nucleic Acids Res 1994, 22:4872-4875.
11. Niermann GL, Buehring GC: Hormone regulation of bovine leukemia virus via the long terminal repeat. Virology 1997, 239:249-258.
12. Brooks PA, Cockerell GL, Nyborg JK: Activation of BLV transcription by NF-kappa B and Tax. Virology 1998, 243: 4-98.
13. Dekoninck A, Calomme C, Nizet S, de Launoit Y, Burny A, Ghysdael J, Van Lint C: Identification and characterization of a PU.1/ Spi-B binding site in the bovine leukemia virus long terminal repeat. Oncogene 2003, 22:2882-2896.
14. Boris_Lawrie K, Altanerova V, Altaner C, Kucerova L, Temin HM: In vivo study of genetically simplified bovine leukemia virus derivatives that lack tax and rex. Journal of Virology 1997, 71:1514-1520.
15. Van Der Maaten MJ, Miller JM: Replication of bovine leukemia virus in monolayer cell cultures. Bibl Haematol 1975:360-362.
16. Harms JS, Splitter GA: Loss of MHC I transcription trans-activator in the bovine B-LCL, BL3.1. Veterinary Immunology and Immunopathology 1996, 51:39-54.
17. Szynal M, Cleuter Y, Beskorwayne T, Bagnis C, Van Lint C, Kerkhofs P, Burny A, Martiat P, Griebel P, Van den Broeke A: Disruption of B-cell homeostatic control mediated by the BLV-Tax oncoprotein: Association with the upregulation of Bcl-2 and signaling through NF-kappaB. Oncogene 2003, 22:4531-4542.
18. Harms JS, Splitter GA: CD8+ lymphocytes that kill allogeneic and xenogeneic major histocompatibility complex class I targets. Hum Immunol 1995, 44:50-57.
19. Zufferey R, Donello JE, Trono D, Hope TJ: Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors. J Virol 1999, 73:2886-2892.
20. Loeb JE, Cordier WS, Harris ME, Weitzman MD, Hope TJ: Enhanced expression of transgenes from adeno-associated virus vectors with the woodchuck hepatitis virus posttranscriptional regulatory element: Implications for gene therapy. Hum Gene Ther 1999, 10:2295-2305.
21. Willems L, Romond PC, Ghysdael J, Burny A, Kettmann R: The bovine leukemia virus tax gene contains an enhancer sequence. Virology 1991, 182:130-134.
22. Tajima S, Takahashi M, Takeshima SN, Konnai S, Yin SA, Watarai S, Tanaka Y, Onuma M, Okada K, Aida Y: A mutant form of the tax protein of bovine leukemia virus (BLV), with enhanced transactivation activity, increases expression and propagation of BLV in vitro but not in vivo. Journal of Virology 2003, 77:1894-1903.
23. Merezak C, Reichert M, Van Lint C, Kerkhofs P, Portetelle D, Willems L, Kettmann R: Inhibition of histone deacetylases induces bovine leukemia virus expression in vitro and in vivo. J Virol 2002, 76:5034-5042.
24. Boshart M, Weber F, Jahn G, Dorsch-Hasler K, Fleckenstein B, Schaffner W: A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus. Cell 1985, 41: 21-530.
25. Furth PA, Hennighausen L, Baker C, Beatty B, Woychick R: The variability in activity of the universally expressed human cytomegalovirus immediate early gene 1 enhancer/promoter in transgenic mice. Nucleic Acids Res 1991, 19:6205-6208.
26. Mizuguchi H, Xu ZL, Sakurai F, Mayumi T, Hayakawa T: Tight positive regulation of transgene expression by a single adenovirus vector containing the rtTA and tTS expression cassettes in separate genome regions. Hum Gene Ther 2003, 14:1265-1277.
27. Calomme C, Nguyen TL, de Launoit Y, Kiermer V, Droogmans L, Burny A, Van Lint C: Upstream stimulatory factors binding to an E box motif in the R region of the bovine leukemia virus long terminal repeat stimulates viral gene expression. The Journal of Biological Chemistry 2002, 277:8775-8789.
28. Tana, Watarai S, Aida Y, Tajima S, Kakidani H, Onuma M, Kodama H: Growth inhibition of cancer cells by co-transfection of diphtheria toxin A-chain gene plasmid with bovine leukemia virus-tax expression vector. Microbiology and Immunology 2001, 45: 47-455.
29. Van den Broeke A, Cleuter Y, Beskorwayne T, Kerkhofs P, Szynal M, Bagnis C, Burny A, Griebel P: CD154 costimulated ovine primary B cells, a cell culture system that supports productive infection by bovine leukemia virus. J Virol 2001, 75:1095-1103.
30. Xiao J, Buehring GC: In vivo protein binding and functional analysis of cis-acting elements in the U3 region of the bovine leukemia virus long terminal repeat. Journal of Virology 1998, 72:5994-6003.
31. Kerkhofs P, Heremans H, Burny A, Kettmann R, Willems L: In vitro and in vivo oncogenic potential of bovine leukemia virus G4 protein. J Virol 1998, 72:2554-2559.
32. Grunstein M: Histone acetylation in chromatin structure and transcription. Nature 1997, 389:349-352.
33. Twizere JC, Kerkhofs P, Burny A, Portetelle D, Kettmann R, Willems L: Discordance between bovine leukemia virus tax immortalization in vitro and oncogenicity in vivo. J Virol 2000, 74:9895-9902.
34. Willems L, Grimonpont C, Kerkhofs P, Capiau C, Gheysen D, Conrath K, Roussef R, Mamoun R, Portetelle D, Burny A, et al.: Phosphorylation of bovine leukemia virus Tax protein is required for in vitro transformation but not for transactivation. Oncogene 1998, 16:2165-2176.