The CREB, ATF-1, and ATF-2 transcription factors from bovine leukemia virus-infected B lymphocytes activate viral expression

Journal of Virology

Volumn 70, Issue 3, 1996, Pages 1990-1999

  Adam, Emmanuelle ^a,c   Kerkhofs, Pierre ^b   Mammerickx, Marc ^b   Burny, Arséne ^a,c   Kettmann, Richard ^c   Willems, Lucas ^c  

^a FREE UNIVERSITY OF BRUSSELS   (Belgium)

^b Belgian National Institute for Veterinary Research   (Belgium)

^c UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; BOVINE LEUKEMIA VIRUS; LYMPHOCYTOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; RNA VIRUS INFECTION; VIRUS EXPRESSION; VIRUS PATHOGENESIS; VIRUS REPLICATION; VIRUS TRANSCRIPTION;

EID: 0030043806     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.70.3.1990-1999.1996     Document Type: Article

References (81)

1. Adam, E., P. Kerkhofs, M. Mammerickx R. Kettmann, A. Burny, L. Droogmans, and L. Willems. 1994. Involvement of the cyclic AMP-responsive element binding protein in bovine leukemia virus expression in vivo J. Virol. 68:5845-5853.
2. Anderson, M. G., and W. S. Dynan. 1994. Quantitative studies of the effect of HTLV-1 Tax protein on CREB protein-DNA binding. Nucleic Acids Res. 22:3194-3201.
3. Armstrong, A. P., A. A. Franklin, M. N. Ulttenbogaard, H. A. Giebler, and J. K. Nyborg. 1993 Pleiotropic effect of the human T-cell leukemia virus Tax protein on the DNA binding activity of eukaryotic transcription factors Proc Natl. Acad. Sci. USA 90:7303-7307.
4. Baliga, V., and J. F. Ferrer. 1977. Expression of the bovine leukemia virus and its internal antigen in blood lymphocytes. Proc. Soc. Exp Biol. Med. 156:388-391.
5. Baranger, A. M., C. Rodgers Palmer, M. K. Hamm, H. A. Giebler, A. Brauweiler, J. K. Nyborg, and A. Schepartz. 1995. Mechanism of DNA-binding enhancement by the human T-cell leukaemia virus transactivator Tax Nature (London) 376:606-608.
6. Berridge, M. J. 1993. Inositol triphosphate and calcium signalling. Nature (London) 361:315-325.
7. Berridge, M. J., and R. F. Irvine, 1984 Inositol triphosphate, a novel second messenger in cellular signal transducing. Nature (London) 312:315-321.
8. Bijsterbosch, M. K., C. J. Meade, G. A. Turner, and G. G. B. Klaus. 1985. B lymphocyte receptors and phosphoinositide degradation Cell 41:999-1006.
9. Boyle, W. J., T. Smeal, L. H. K. Defize, P. Angel, J. R. Woodgett, M. Karin, and T. Hunter. 1991. Activation of protein kinase C decreases phosphorylation of c-jun at sites that negatively regulate its DNA-binding activity. Cell 64:573-584.
10. Brash, D., R. Reddel, M. Quanrud, K. Yang, M. Farrel, and C. Harris. 1987. Strontium phosphate transfection of human cells in primary culture: stable expression of the simian virus 40 large T-antigen gene in primary human bronchial epithelial cells. Mol. Cell. Biol. 7:2031-2034.
11. Brauweiler, A., P. Garl, A. A. Franklin, H. A. Giebler, and J. K. Nyborg. 1995. A molecular mechanism for human T-cell leukemia virus latency and Tax transcativation. J Biol. Chem 270:12814-12822.
12. Brooks, A. P., J. K. Nyborg, and G. L. Cockerell. 1995. Identification of an NF-κB binding site in the bovine leukemia virus promoter. J. Virol. 69:6005-6009.
13. Burny, A., C. Bruck, Y. Cleuter, D. Couez, J. Deschamps, D. Gregoire, J. Ghysdael, R. Kettmann, M. Mammerickx, G. Marbaix, and D. Portetelle. 1985. Bovine leukaemia virus and enzootic bovine leukosis. Onderstepoort J. Vet. Res. 52:133-134
14. Connor, L. M., M. N. Oxman, J. N. Brady, and S. J. Marriott. 1993. Twenty-one base pair repeat elements influence the ability of a GAL4-Tax fusion protein to transactivate the HTLV-I long terminal repeat. Virology 195:569-577
15. 2+/calmodulin as well as cAMP-dependent protein kinase. Proc. Natl. Acad Sci. USA 88:5061-5065.
16. de Groot, R. P., R. Derma, J. Goris, and P. Sassone-Corsi. 1993 Phosphorylation and negative regulation of the transcriptional activator CREM by p34cdc2. Mol. Endocrinol 7:1495-1501.
17. Derse, D. 1987. Bovine leukemia virus transcription is controlled by a virus-encoded trans-acting factor and by cis-acting response elements. J. Virol. 61:2462-2471.
18. Ellis, M. J. C., A. C. Lindon, K. J. Flint, N. C. Jones, and S. Goodbourn. 1995. Activating transcription factor-1 is a specific, antagonist of the cyclic adenosine 3′,5′-monophosphate (cAMP) response element-binding protein-1-mediated response to cAMP. Mol. Endocrinol. 9:255-265.
19. 2+/calmodulin-dependent protein kinase IV. J. Biol. Chem 269:15520-15527.
20. Enslen, H., H. Tokumitsu, and T. R. Soderling. 1995 Phosphorylation of CREB by CaM-kinase IV activated by CaM-kinase IV kinase. Biochem. Biophys. Res. Commun. 207:1038-1043
21. Franklin, A. A., M. F. Kubik, M. N. Uittenbogaard, A. Brauweiler, P. Utaisincharoen, M.-A. H. Matthews, W. S. Dynan, J. P. Hoeffler, and J. K. Nyborg. 1993 Transactivation by the human T-cell leukemia virus Tax protein is mediated through enhanced binding of activating transcription factor-2 (ATF-2) ATF-2 response and cAMP element-binding protein (CREB). J. Biol. Chem 268:21225-21231.
22. Fujii, M., H. Tsuchiya, and M. Seiki. 1991 HTLV-1 Tax has distinct but overlapping domains for transcriptional activation and for enhancer specificity. Oncogene 6:2349-2352.
23. Fujisawa, J.-I., M. Toita, T. Yoshimura, and M. Yoshida. 1991. The indirect association of human T-cell leukemia virus Tax proteins with DNA results in transcriptional activation. J. Virol 65:4525-4528
24. Ghysdael, J., C. Bruck, R. Kettmann, and A. Burny. 1984 Bovine leukemia virus. Curr. Top Microbiol. Immunol 112:1-19
25. Ginty, D. D., A. Bonni, and M. E. Greenberg. 1994. Nerve growth factor activates a Ras-dependent protein kinase that stimulates c-fos transcription via phosphorylation ot CREB. Cell 77:713-725.
26. Gonzalez, G. A., P. Menzel, J. Leonard, W. H. Fischer, and M. R. Montminy. 1991. Characterization of motifs which are critical for activity of the cyclic AMP-responsive transcription factor CREB. Mol Cell. Biol 11:1306-1312.
27. Gonzalez, G. A., and M. R. Montminy. 1989 Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. Cell 59:675-680.
28. Gonzalez, G. A., K. K. Yamamoto, W. H. Fisher, D. Karr, P. Menzel, W. Biggs III, W. W. Vale, and M. R. Montminy. 1989. A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence Nature (London) 337:749-752.
29. Gupta, P., and J. F. Ferrer. 1982. Expression of bovine leukemia virus genome is blocked by a non-immunoglobulin protein in plasma from infected cattle. Science 215:405-407.
30. Hai, T., F. Liu, W. J. Coukos, and M. R. Green. 1989. Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers. Genes Dev. 8:2083-2090.
31. 2-/calmodulin-dependent protein kinase. CaM kinase-Gr, in human T lymphocytes J. Biol. Chem. 268:20055-20063.
32. Hoeffler, J. P., J. W. Lustbader, and C.-Y. Chen. 1991. Identification of multiple nuclear factors that interact with cyclic adenosine 3′,5′-monophosphate response element binding protein and activating transcription factor-2 by protein-protein interaction. EMBO J. 9:225-232.
33. Hoeffler, J. P., T. E. Meyer, Y. Yun, J. L. Jameson, and J. F. Habener. 1988. Cyclic AMP-responsive DNA-binding protein: structure based on a cloned placental cDNA. Science 242:1430-1433.
34. Hurst, H. C., N. Masson, N. C. Jones, and K. A. W. Lee. 1990. The cellular transcription factor CREB corresponds to activating transcription factor 47 (ATF-47) and forms complexes with a group of polypeptides related to ATF-43 Mol. Cell. Biol. 10:6192-6203.
35. Hurst, H. C., N. F. Totty, and N. C. Jones. 1991. Identification and functional characterisation of the cellular activating transcription factor 43 (ATF-43) protein Nucleic Acids Res. 19:4601-4609.
36. 2-/calmodulin-dependent protein kinase in GH3 cells. J. Biol. Chem. 266:1484-1490.
37. Jensen, W. A., B. J. Wicks-Beard, and G. L. Cockerell. 1992. Inhibition of protein kinase C results in decreased expression of bovine leukemia virus. J. Virol. 66:4427-4433.
38. 2+/calmodulin-dependent protein kinase IV gene. FEBS Lett. 289:105-109.
39. Kara, C. J., H.-C. Liou, L. B. Ivashkiv, and L. H. Glimcher. 1990. A cDNA for a human cyclic AMP response element-binding protein which is distinct from CREB and expressed preferentially in brain. Mol. Cell. Biol. 10:1347-1357.
40. Karpinski, B. A., G. D. Morle, J. Huggenvik, M. D. Uhler, and J. M. Leiden. 1992 Molecular cloning of human CREB-2 an ATF/CREB transcription factor that can negatively regulate transcription from the cAMP response element Proc. Natl. Acad. Sci USA 89:4820-4824.
41. max activates heterologous promoters with a common sequence known as a cAMP-responsive element or the binding site of a cellular transcription factor ATF. EMBO J. 8:497-503.
42. Kettmann, R., A. Burny, I. Callebaut, L. Droogmans, M. Mammerickx, L. Willems, and D. Portetelle. 1994. Bovine leukemia virus, p. 39-81. In J. A. Levy (ed.). The Retroviridae, vol. 3. Plenum Press, New York.
43. Kettmann, R., Y. Cleuter, M. Mammerickx, M. Meunier-Rotival, G. Bernardi, A. Burny, and H. Chantrenne. 1980. Genomic integration of bovine leukemia provirus: comparison of persistent lymphocytosis with lymph node tumor form of enzootic bovine leukosis. Proc. Natl Acad. Sci. USA 77:2577-2581.
44. Kettmann, R., G. Marbaix, Y. Cleuter, D. Portetelle, M. Mammerickx, and A. Burny. 1980. Genomic integration of bovine leukemia provirus and lack of viral RNA expression in the target cells of cattle with different responses to BLV infection. Leuk. Res. 4:509-519.
45. Kumar, S. P., P. S. Paul, and K. A. Pomeroy. 1978 Frequency of lymphocytes bearing Fc receptors and surface membrane immunoglobulins in normal, persistent lymphocytotic and leukemic cows. Am. J. Vet. Res 39:45-49.
46. Lagarias, D. M., and K. Radke. 1989. Transcriptional activation of bovine leukemia virus in blood cells from experimentally infected, asymptomatic sheep with latent infections. J. Virol. 63:2099-2107.
47. Lee, C. Q., Y. Yun, J. P. Hoeffler, and J. F. Habener. 1990 Cyclic AMP responsive transcriptional activation of CREB-327 involves interdependent phosphorylated subdomains. EMBO J. 9:4455-4465.
48. Lin, Y.-S., and M. R. Green. 1988 Interaction of a common cellular transcription factor. ATF, with regulatory elements in both E1a- and cyclic AMP-inducible promoters Proc. Natl. Acad. Sci. USA 85:3396-3400.
49. Maekawa, T., H. Sakura, C. Kanei-Ishii, T. Sudo, T. Yoshimura, J. Fujisawa, M. Yoshida, and S. Ishii. 1989 Leucine zipper structure of the protein CRE-BP1 binding to the cyclic AMP response element in brain. EMBO J. 8:2023-2028.
50. Matthews, M.-A. H., R.-B. Markowitz, and W. S. Dynan. 1992. In vitro activation of transcription by the human T-cell leukemia virus type I Tax protein. Mol. Cell. Biol. 12:1986-1996.
51. Matthews, R. P., C. R. Guthrie, L. M. Wailes, X. Zhao, A. R. Means, and G. S. McKnight. 1994. Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression. Mol. Cell Biol 14:6107-6116.
52. 2+/calmodulin-dependent protein kinase and a male germ cell-specific calmodulin-binding protein die derived from the same gene. Mol. Cell. Biol. 11:3960-3971.
53. Miller, J. M., L. S. Miller, C. Olson, and D. G. Gilette. 1969 Virus-like particles in phytohemagglutinin-stimulated lymphocyte cultures with reference to bovine lymphosarcoma. J. Natl. Cancer Inst. 43:1297-1305.
54. Montminy, M. R., and L. M. Bilezikjian. 1987. Binding of a nuclear protein to the cyclic AMP response element of the somatostatin gene. Nature (London) 328:175-178.
55. Montminy, M. R., K. A. Sevarino, J. A. Wagner, G. Mandel, and R. H. Goodman. 1986. Identification of a cyclic-AMP-response element within the rat somatostatin gene. Proc. Natl. Acad. Sci USA 83:6682-6686
56. 2-/calmodulin-dependent protein kinase. CaM kinase-Gr, expressed after transformation of primary human B lymphocytes by Epstein-Barr virus (EBV) is induced by the EBV oncogene LMP1 J. Virol. 68:1697-1705.
57. Nishizuka, Y. 1984. The role of protein kinase C in cell surface signal transducing and tumor promotion. Nature (London) 308:693-697.
58. Ofir, R., V. J. Dwarki, D. Rashid, and I. M. Verma. 1990. Phosphorylation of the C terminus of Fos protein is required for transcriptional transrepression of the c-fos promoter Nature (London) 348:80-82.
59. Onuma, M., T. Honma, T. Mikami, S. Ichijo, and T. Konishi. 1979 Studies on the sporadic and enzootic forms of bovine leukosis. J. Comp. Pathol. 89:159-167.
60. Onuma, M., N. Sagata, K. Okada, Y. Ogawa, Y. Ikawa, and I. Oshima. 1982. Integration of bovine leukemia virus DNA in the genomes of bovine lymphosarcoma cells Microbiol. Immunol. 26:813-820.
61. Perini, G., S. Wagner, and M. R. Green. 1995. Recognition of bZIP proteins by the human T-cell leukaemia virus transactivator Tax. Nature (London) 376:602-605.
62. Sheng, M., G. McFadden, and M. R. Greenberg. 1990. Membrane depolarization and calcium induced c-fos transcription via phosphorylation of transcription factor CREB. Neuron 4:571-582.
63. 2--related transcription factor phosphorylated by calmodulin-dependent kinases. Science 252:1427-1430.
64. Singh, H., J. Lebowitz, A. Baldwin, and P. Sharp. 1988. Molecular cloning of an enhancer binding protein: isolation by screening of an expression library with a recognition site DNA Cell 52:415-423.
65. Srebrow, A., A. F. Muro, S. Werbajh, P. A. Sharp, and A. R. Kornblihtt. 1993. The CRE-binding factor ATF-2 facilitates the occupation of the CCAAT box in the fibronectin gene promoter. FEBS Lett 327:25-28.
66. Stock, N. D., and J. F. Ferrer. 1972. Replicating C-type virus in phytohemagglutinin-treated buffy coat cultures of bovine origin J. Natl Cancer Inst. 48:985-996.
67. 2+/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity. Genes Dev. 8:2527-2539.
68. Suzuki, T., J.-I. Fujisawa, M. Toita, and M. Yoshida. 1993 The transactivator Tax of human T-cell leukemia virus type 1 (HTLV-1) interacts with the cAMP-responsive element (CRE) binding and CRE modulator proteins that bind to the 21-base-pair enhancer of HTLV-1. Proc. Natl. Acad. Sci USA 90:610-614.
69. Thurmond, M. C., C. A. Holmberg, and J. P. Picanso. 1985. Antibodies to bovine leukemia virus and presence of malignant lymphoma in slaughtered California dairy cattle. JNCI 74:711-714.
70. Tratner, I., R. Ofir, and I. M. Verma. 1992. Alteration of a cyclic AMP-dependent protein kinase phosphorylation site in the c-Fos protein augments its transforming potential. Mol. Cell. Biol 12:998-1006.
71. Tsuchiya, H., M. Fujii, Y. Tanaka, H. Tozawa, and M. Seiki. 1994 Two distinct regions from a functional activation domain of the HTLV-I transactivator Tax1. Oncogene 9:337-340.
72. Van den Broeke, A., Y. Cleuter, G. Chen, D. Portetelle, M. Mammerickx, D. Zagury, M. Fouchard, L. Coulombel, R. Kettmann, and A. Burny. 1988. Even transcriptionally competent proviruses are silent in bovine leukemia virus-induced sheep tumor cells. Proc. Natl. Acad. Sci. USA 85:4263-9267.
73. Wagner, S., and M. R. Green. 1993. HTLV-I Tax protein stimulation of DNA binding of bZIP proteins by enhancing dimerization. Science. 262:395-399.
74. Weiland, F., and O. S. Straub. 1976. Differences in the in vitro responses of lymphocytes from leukotic and normal cattle to concanavalin A Res. Vet. Sci. 20:340-341.
75. Willems, L., A. Gegonne, G. Chen, A. Burny, R. Kettmann, and J. Ghysdael. 1987. The bovine leukemia virus p34 is a transactivator protein EMBO J 6:3385-3389.
76. Willems, L., R. Kettmann, G. Chen. D. Portetelle, A. Burny, and D. Derse. 1991. Nucleotide sequence of the bovine cyclic-AMP responsive DNA binding protein (CREB2) cDNA J DNA Sequencing Mapping 1:415-417.
77. Willems, L., R. Kettmann, G. Chen, D. Portetelle, A. Burny, and D. Derse. 1992. A cyclic AMP-responsive DNA-binding protein (CREB2) is a cellular transactivator of the bovine leukemia virus long terminal repeat. J Virol 66:766-772.
78. Xie, H., and T. L. Rothstein. 1995. Protein kinase C mediates activation of nuclear cAMP response element-binding protein (CREB) in B lymphocytes stimulated through surface Ig. J. Immunol. 154:1717-1723.
79. Yamamoto, K. K., G. A. Gonzalez, W. H. Biggs III. and M. R. Montminy. 1988. Phosphorylation-induced binding and transcriptional efficiency of nuclear factor CREB Nature (London) 334:494-498.
80. Zandomeni, R. O., M. Carrera-Zandomeni, E. Esteban, W. Donawick, and J. F. Ferrer. 1992. Induction and inhibition of bovine leukaemia virus expression in naturally infected cells. J Gen. Virol. 73:1915-1924.
81. Zhao, L.-J., and C.-Z. Giam. 1992 Human T-cell lymphotrophic virus type I (HTLV-I) transcriptional activator Tax enhances CREB binding to HTLV-I 21-base-pair repeats by protein-protein interaction Proc. Natl. Acad. Sci. USA 89:7070-7074