Persistence of K-ras mutations in plasma after colorectal tumor resection

Anticancer Research

Volumn 25, Issue 1 B, 2005, Pages 657-661

  Lindforss, Ulrik ^a   Zetterquist, Henrik ^a   Papadogiannakis, Nikos ^a   Olivecrona, Hans ^b  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b STOCKHOLM SÖDER HOSPITAL   (Sweden)

Author keywords

Circulating nucleic acids; Colorectal carcinoma; K ras mutations; TGGE (temperature gradient electrophoresis)

Indexed keywords

ADULT; AGED; ARTICLE; CANCER INVASION; CANCER RECURRENCE; CANCER STAGING; CANCER SURGERY; CLINICAL ARTICLE; COLORECTAL TUMOR; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA DETERMINATION; EARLY DIAGNOSIS; FEMALE; FOLLOW UP; GEL ELECTROPHORESIS; GENE AMPLIFICATION; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MICROSCOPIC ANATOMY; ONCOGENE K RAS; POLYMERASE CHAIN REACTION; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; PRIORITY JOURNAL; RECURRENT DISEASE; SOLID TUMOR; TUMOR BIOPSY;

AGED; AGED, 80 AND OVER; BIOPSY; CARCINOMA; COLORECTAL NEOPLASMS; DNA; DNA, NEOPLASM; ELECTROPHORESIS; FEMALE; GENES, RAS; HUMANS; MALE; MIDDLE AGED; MUTATION; RECURRENCE; TIME FACTORS;

EID: 16344382732     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Leon SA, Shapiro B, Sklaroff DM and Yaros MJ: Free DNA in the serum of cancer patients and the effect of therapy. Cancer Res 37: 646-650, 1977.
2. Shapiro B, Chakrabarty M, Cohn EM and Leon SA: Determination of circulating DNA levels in patients with benign or malignant gastrointestinal disease. Cancer 51: 2116-2120, 1983.
3. Anker P, Lefort F, Vasioukhin V, Lyautey J, Lederrey C, Chen XQ, Stroun M, Mulcahy HE and Farthing MJ: K-ras mutations are found in DNA extracted from the plasma of patients with colorectal cancer. Gastroenterology 112: 1114-1120, 1997.
4. Kopreski MS, Benko FA, Kwee C, Leitzel KE, Eskander E, Lipton A and Gocke CD: Detection of mutant K-ras DNA in plasma or serum of patients with colorectal cancer. Br J Cancer 76: 1293-1299, 1997.
5. de Kok JB, van Solinge WW, Ruers TJ, Roelofs RW, van Muijen GN, Willems JL and Swinkels DW: Detection of tumour DNA in serum of colorectal cancer patients. Scand J Clin Lab Invest 57: 601-604, 1997.
6. Ito S, Hibi K, Nakayama H, Kodera Y, Ito K, Akiyama S and Nakao A: Detection of tumor DNA in serum of colorectal cancer patients. Jpn J Cancer Res 93: 1266-1269, 2002.
7. Hibi K, Robinson CR, Booker S, Wu L, Hamilton SR, Sidransky D and Jen J: Molecular detection of genetic alterations in the serum of colorectal cancer patients. Cancer Res 58: 1405-1407, 1998.
8. Lindforss U, Papadogiannakis N, Zetterquist H, Lindberg G and Olivecrona H: Distribution of genetic variants in preneoplastic areas of colorectal tumours. Eur J Surg Oncol 29: 491-496, 2003.
9. Mulcahy HE, Lyautey J, Lederrey C, Chen XQ, Lefort F, Vasioukhin V, Anker P, Alstead EM, Farthing MJ and Stroun M: Plasma DNA K-ras mutations in patients with gastrointestinal malignancies. Ann N Y Acad Sci 906: 25-28, 2000.
10. Pajkos G, Kiss I, Sandor J, Ember I and Kishazi P: The prognostic value of the presence of mutations at the codons 12, 13, 61 of K-ras oncogene in colorectal cancer. Anticancer Res 20: 1695-1701, 2000.
11. Bos JL, Fearon ER, Hamilton SR, Verlaan-de Vries M, van Boom JH, van der Eb AJ and Vogelstein B: Prevalence of ras gene mutations in human colorectal cancers. Nature 327: 293-297, 1987.
12. George SM, Makinen MJ, Jernvall P, Makela J, Vihko P and Karttunen TJ: Classification of advanced colorectal carcinomas by tumor edge morphology: evidence for different pathogenesis and significance of polypoid and nonpolypoid tumors. Cancer 89: 1901-1909, 2000.
13. Kusaka T, Fukui H, Sano Y, Ueda Y, Chiba T and Fujimori T: Analysis of K-ras codon 12 mutations and p53 overexpression in colorectal nodule-aggregating tumors. J Gastroenterol Hepatol 15: 1151-1157, 2000.
14. Esteller M, Gonzalez S, Risques RA, Marcuello E, Mangues R, Germa JR, Herman JG, Capella G and Peinado MA: K-ras and p 16 aberrations confer poor prognosis in human colorectal cancer. J Clin Oncol 19: 299-304, 2001.
15. Salbe C, Trevisiol C, Ferruzzi E, Mancuso T, Nascimbeni R, Di Fabio F, Salerni B and Dittadi R: Molecular detection of codon 12 K-ras mutations in circulating DNA from serum of colorectal cancer patients. Int J Biol Markers 15: 300-307, 2000.
16. Font A, Abad A, Monzo M, Sanchez JJ, Guillot M, Manzano JL, Pinol M, Ojanguren I and Rosell R: Prognostic value of K-ras mutations and allelic imbalance on chromosome 18q in patients with resected colorectal cancer. Dis Colon Rectum 44: 549-557, 2001.
17. van Engeland M, Roemen GM, Brink M, Pachen MM, Weijenberg MP, de Bruine AP, Arends JW, van den Brandt PA, de Goeij AF and Herman JG: K-ras mutations and RASSF1A promoter methylation in colorectal cancer. Oncogene 21: 3792-3795, 2002.
18. Lindforss U, Fredholm H, Papadogiannakis N, Gad A, Zetterquist H and Olivecrona H: Allelic loss is heterogeneous throughout the tumor in colorectal carcinoma. Cancer 88: 2661-2667, 2000.
19. Gullberg K, Lindforss U, Zetterquist H, Stalberg D, Reinholt FP, Veress B, Tribukait B, Olivecrona H and Lofberg R: Cancer risk assessment in long-standing pouchitis. DNA aberrations are rare in transformed neoplastic pelvic pouch mucosa. Int J Colorectal Dis 17: 92-97, 2002.
20. Riesner D, Steger G, Zimmat R, Owens RA, Wagenhofer M, Killen W, Vollbach S and Henco K: Temperature-gradient gel electrophoresis of nucleic acids: analysis of conformational transitions, sequence variations and protein-nucleic acid interactions. Electrophoresis 10: 377-389, 1989.
21. Anker P, Lyautey J, Lefort F, Lederrey C and Stroun M: Transformation of NIH/3T3 cells and SW 480 cells displaying K-ras mutation. C R Acad Sci III 317: 869-874, 1994.
22. Perlin E and Moquin RB: Serum DNA levels in patients with malignant disease. Am J Clin Pathol 58: 601-602, 1972.
23. Sorenson GD, Pribish DM, Valone FH, Memoli VA, Bzik DJ and Yao SL: Soluble normal and mutated DNA sequences from single-copy genes in human blood. Cancer Epidemiol Biomarkers Prev 3: 67-71, 1994.
24. Brink M, de Goeij AF, Weijenberg MP, Roemen GM, Lentjes MH, Pachen MM, Smits KM, de Bruine AP, Goldbohm RA and van den Brandt PA: K-ras oncogene mutations in sporadic colorectal cancer in The Netherlands Cohort Study. Carcinogenesis 24: 703-710, 2003.
25. Borchers R, Heinzlmann M, Zahn R, Witter K, Martin K, Loeschke K and Folwaczny C: K-ras mutations in sera of patients with colorectal neoplasias and long-standing inflammatory bowel disease. Scand J Gastroenterol 37: 715-718, 2002.
26. Henco K, Harders J, Wiese U and Riesner D: Temperature gradient gel electrophoresis (TGGE) for the detection of polymorphic DNA and RNA. Methods Mol Biol 31: 211-228, 1994.
27. Thijssen MA, Swinkels DW, Ruers TJ and de Kok JB: Difference between free circulating plasma and serum DNA in patients with colorectal liver metastases. Anticancer Res 22: 421-425, 2002.
28. Fidler IJ: The relationship of embolic homogeneity, number, size and viability to the incidence of experimental metastasis. Eur J Cancer 9: 223-227, 1973.