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Volumn 18, Issue 2, 2005, Pages 75-83

Pharmacokinetic alterations of antimicrobials in the critically ill

Author keywords

Adult; Antimicrobials; Critical illness; Pharmacokinetics

Indexed keywords

ALUMINUM; ANTACID AGENT; ANTIINFECTIVE AGENT; BETA LACTAM; CALCIUM; CEFEPIME; CEFTRIAXONE; CEPHALOSPORIN; CIPROFLOXACIN; CLINDAMYCIN; ERYTHROMYCIN; FLUCONAZOLE; HYPERTENSIVE AGENT; IMIPENEM; KETOLIDE; LEVOFLOXACIN; LINEZOLID; MAGNESIUM; MEROPENEM; METHYLPREDNISOLONE; METOCLOPRAMIDE; MIDAZOLAM; NAFCILLIN; NALOXONE; OXAZOLIDINONE DERIVATIVE; PIPERACILLIN; TOBRAMYCIN; TRIAZOLE DERIVATIVE; UNINDEXED DRUG; VANCOMYCIN;

EID: 16344380591     PISSN: 08971900     EISSN: None     Source Type: Journal    
DOI: 10.1177/0897190004273568     Document Type: Review
Times cited : (3)

References (73)
  • 2
    • 0036438587 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic considerations when treating patients with sepsis and septic shock
    • De Paepe P, Belpaire FM, Buylaert WA. Pharmacokinetic and pharmacodynamic considerations when treating patients with sepsis and septic shock. Clin Pharmacokinet. 2002;41:1135-1151.
    • (2002) Clin Pharmacokinet , vol.41 , pp. 1135-1151
    • De Paepe, P.1    Belpaire, F.M.2    Buylaert, W.A.3
  • 3
    • 0031751331 scopus 로고    scopus 로고
    • Effects of surgery on the pharmacokinetic parameters of drugs
    • Kennedy JM, Van Riji AM. Effects of surgery on the pharmacokinetic parameters of drugs. Clin Pharmacokinet. 1998;35:293-312.
    • (1998) Clin Pharmacokinet , vol.35 , pp. 293-312
    • Kennedy, J.M.1    Van Riji, A.M.2
  • 5
    • 0023262397 scopus 로고
    • The effect of nutritional support on outcome from severe head injury
    • Young B, Ott L, Twyman D, et al. The effect of nutritional support on outcome from severe head injury. J Neurosurg. 1987;67:668-676.
    • (1987) J Neurosurg , vol.67 , pp. 668-676
    • Young, B.1    Ott, L.2    Twyman, D.3
  • 6
    • 0035674699 scopus 로고    scopus 로고
    • Early enteral nutrition in acutely ill patients: A systematic review
    • Marik PE, Zaloga GP. Early enteral nutrition in acutely ill patients: a systematic review. Crit Care Med. 2001;29:2264-2270.
    • (2001) Crit Care Med , vol.29 , pp. 2264-2270
    • Marik, P.E.1    Zaloga, G.P.2
  • 7
    • 0031736708 scopus 로고    scopus 로고
    • Pharmacokinetics and absolute bioavailability of ciprofloxacin administered through a nasogastric tube with continuous enterai feeding to critically ill patients
    • Mimoz O, Binter V, Jacolot A, et al. Pharmacokinetics and absolute bioavailability of ciprofloxacin administered through a nasogastric tube with continuous enterai feeding to critically ill patients. Intensive Care Med. 1998;24:1047-1051.
    • (1998) Intensive Care Med , vol.24 , pp. 1047-1051
    • Mimoz, O.1    Binter, V.2    Jacolot, A.3
  • 8
    • 0031898961 scopus 로고    scopus 로고
    • Bioavailability of ciprofloxacin after multiple enterai and intravenous doses in ICU patients with severe gram-negative intra-abdominal infections
    • de Marie S, VandenBergh MFQ, Buijk SLCE, et al. Bioavailability of ciprofloxacin after multiple enterai and intravenous doses in ICU patients with severe gram-negative intra-abdominal infections. Intensive Care Med. 1998;24:343-346.
    • (1998) Intensive Care Med , vol.24 , pp. 343-346
    • De Marie, S.1    VandenBergh, M.F.Q.2    Buijk, S.L.C.E.3
  • 9
    • 0034759571 scopus 로고    scopus 로고
    • Pharmacokinetics of fluconazole in trauma patients with postpyloric feeding tubes
    • Davis GA, Rapp RP, Kearney PA, Ensom MH. Pharmacokinetics of fluconazole in trauma patients with postpyloric feeding tubes. Ann Pharmacother. 2001;35:1492-1494.
    • (2001) Ann Pharmacother , vol.35 , pp. 1492-1494
    • Davis, G.A.1    Rapp, R.P.2    Kearney, P.A.3    Ensom, M.H.4
  • 10
    • 0035090910 scopus 로고    scopus 로고
    • Pharmacokinetics of sequential intravenous and enteral fluconazole in critically ill surgical patients with invasive mycoses and compromised gastro-intestinal function
    • Buijk SLCE, Gyssens IC, Mouton JW, Verbrugh HA, Touw DJ, Bruining HA. Pharmacokinetics of sequential intravenous and enteral fluconazole in critically ill surgical patients with invasive mycoses and compromised gastro-intestinal function. Intensive Care Med. 2001;27:115-121.
    • (2001) Intensive Care Med , vol.27 , pp. 115-121
    • Buijk, S.L.C.E.1    Gyssens, I.C.2    Mouton, J.W.3    Verbrugh, H.A.4    Touw, D.J.5    Bruining, H.A.6
  • 13
    • 0033859555 scopus 로고    scopus 로고
    • Effect of dopamine on gastrointestinal motility during critical illness
    • Dive A, Foret F, Jamart J, Bulpa P, Installe E. Effect of dopamine on gastrointestinal motility during critical illness. Intensive Care Med. 2000;26:901-907.
    • (2000) Intensive Care Med , vol.26 , pp. 901-907
    • Dive, A.1    Foret, F.2    Jamart, J.3    Bulpa, P.4    Installe, E.5
  • 15
    • 0033008277 scopus 로고    scopus 로고
    • Metoclopramide improves gastric motility in critically ill patients
    • Jooste CA, Mustoe J, Collee G. Metoclopramide improves gastric motility in critically ill patients. Intensive Care Med. 1999;25:464-468.
    • (1999) Intensive Care Med , vol.25 , pp. 464-468
    • Jooste, C.A.1    Mustoe, J.2    Collee, G.3
  • 16
    • 1142298595 scopus 로고    scopus 로고
    • Enteral administration of naloxone for treatment of opioid-associated intragastric feeding intolerance
    • Mixides G, Liebl MG, Bloom K. Enteral administration of naloxone for treatment of opioid-associated intragastric feeding intolerance. Pharmacotherapy. 2004;24:291-294.
    • (2004) Pharmacotherapy , vol.24 , pp. 291-294
    • Mixides, G.1    Liebl, M.G.2    Bloom, K.3
  • 17
    • 0036795265 scopus 로고    scopus 로고
    • Pharmacokinetics of intravenous and oral levofloxacin in critically ill adults in a medical intensive care unit
    • Rebuck JA, Fish DN, Abraham E. Pharmacokinetics of intravenous and oral levofloxacin in critically ill adults in a medical intensive care unit. Pharmacotherapy. 2002;22:1216-1225.
    • (2002) Pharmacotherapy , vol.22 , pp. 1216-1225
    • Rebuck, J.A.1    Fish, D.N.2    Abraham, E.3
  • 18
    • 0033536913 scopus 로고    scopus 로고
    • Early switch from intravenous to oral antibiotics and early hospital discharge
    • Ramirez JA, Vargas S, Ritter GW, et al. Early switch from intravenous to oral antibiotics and early hospital discharge. Arch Intern Med. 1999;159:2449-2454.
    • (1999) Arch Intern Med , vol.159 , pp. 2449-2454
    • Ramirez, J.A.1    Vargas, S.2    Ritter, G.W.3
  • 19
    • 0035478105 scopus 로고    scopus 로고
    • Efficacy and safety of oral and early-switch therapy for community-acquired pneumonia: A randomized controlled trial
    • Castro-Guardiola A, Viejo-Rodriguez A-L, Soler-Simon S, et al. Efficacy and safety of oral and early-switch therapy for community-acquired pneumonia: a randomized controlled trial. Am J Med. 2001;111:367-374.
    • (2001) Am J Med , vol.111 , pp. 367-374
    • Castro-Guardiola, A.1    Viejo-Rodriguez, A.-L.2    Soler-Simon, S.3
  • 20
    • 0034025236 scopus 로고    scopus 로고
    • Detection of capillary protein leakage by indocyanine green and glucose dilutions in septic patients
    • Ishihara H, Matsui A, Muraoka M, Tanabe T, Tsubo T, Matsuki A. Detection of capillary protein leakage by indocyanine green and glucose dilutions in septic patients. Crit Care Med. 2000;28:620-626.
    • (2000) Crit Care Med , vol.28 , pp. 620-626
    • Ishihara, H.1    Matsui, A.2    Muraoka, M.3    Tanabe, T.4    Tsubo, T.5    Matsuki, A.6
  • 21
    • 0032168227 scopus 로고    scopus 로고
    • Detection of capillary protein leakage by glucose and indocyanine green dilutions during the early post-burn period
    • Ishihara H, Otomo N, Suzuki A, Takamura K, Tsubo T, Matsuki A. Detection of capillary protein leakage by glucose and indocyanine green dilutions during the early post-burn period. Burns. 1998;26:525-531.
    • (1998) Burns , vol.26 , pp. 525-531
    • Ishihara, H.1    Otomo, N.2    Suzuki, A.3    Takamura, K.4    Tsubo, T.5    Matsuki, A.6
  • 23
    • 0035175633 scopus 로고    scopus 로고
    • Pulmonary and extrapulmonary effects of increased colloid osmotic pressure during endotoxemia in rats
    • Camacho MT, Totapally B, Torbati D, Wolfsdorf J. Pulmonary and extrapulmonary effects of increased colloid osmotic pressure during endotoxemia in rats. Chest. 2001;120:1655-1662.
    • (2001) Chest , vol.120 , pp. 1655-1662
    • Camacho, M.T.1    Totapally, B.2    Torbati, D.3    Wolfsdorf, J.4
  • 24
    • 0029991787 scopus 로고    scopus 로고
    • Population pharmacokinetics of amikacin in critically ill patients
    • Bressolle F, Gouby A, Martinez J-M, et al. Population pharmacokinetics of amikacin in critically ill patients. Antimicrob Agents Chemother. 1996;40:1682-1689.
    • (1996) Antimicrob Agents Chemother , vol.40 , pp. 1682-1689
    • Bressolle, F.1    Gouby, A.2    Martinez, J.-M.3
  • 25
    • 0033670746 scopus 로고    scopus 로고
    • Population pharmacokinetics of aminoglycosides in critically ill trauma patients on once-daily regimens
    • Barletta JF, Johnson SB, Nix DE, Nix LC, Erstad BL. Population pharmacokinetics of aminoglycosides in critically ill trauma patients on once-daily regimens. J Trauma. 2000;49:869-872.
    • (2000) J Trauma , vol.49 , pp. 869-872
    • Barletta, J.F.1    Johnson, S.B.2    Nix, D.E.3    Nix, L.C.4    Erstad, B.L.5
  • 28
    • 0035112931 scopus 로고    scopus 로고
    • Impaired target site penetration of beta-lactams may account for therapeutic failure in patients with septic shock
    • Joukhadar C, Frossard M, Mayer BX, et al. Impaired target site penetration of beta-lactams may account for therapeutic failure in patients with septic shock. Crit Care Med. 2001;29:385-391.
    • (2001) Crit Care Med , vol.29 , pp. 385-391
    • Joukhadar, C.1    Frossard, M.2    Mayer, B.X.3
  • 29
    • 0033933014 scopus 로고    scopus 로고
    • Surgery and intensive care procedures affect the target site distribution of piperacillin
    • Brunner M, Pernerstorfer T, Mayer BX, Eichler HG, Muller M. Surgery and intensive care procedures affect the target site distribution of piperacillin. Crit Care Med. 2000;28:1754-1759.
    • (2000) Crit Care Med , vol.28 , pp. 1754-1759
    • Brunner, M.1    Pernerstorfer, T.2    Mayer, B.X.3    Eichler, H.G.4    Muller, M.5
  • 30
    • 0037789570 scopus 로고    scopus 로고
    • Penetration of piperacillin and tazobactam into pneumonic human lung tissue measured by in vivo microdialysis
    • Tomaselli F, Dittrich P, Maier A, et al. Penetration of piperacillin and tazobactam into pneumonic human lung tissue measured by in vivo microdialysis. Br J Clin Pharmacol. 2002;55:620-624.
    • (2002) Br J Clin Pharmacol , vol.55 , pp. 620-624
    • Tomaselli, F.1    Dittrich, P.2    Maier, A.3
  • 32
    • 0028215145 scopus 로고
    • Behavior of antibiotics during human necrotizing pancreatitis
    • Bassi C, Pederzoli P, Vesentini S, et al. Behavior of antibiotics during human necrotizing pancreatitis. Antimicrob Agents Chemother. 1994;38:830-836.
    • (1994) Antimicrob Agents Chemother , vol.38 , pp. 830-836
    • Bassi, C.1    Pederzoli, P.2    Vesentini, S.3
  • 33
    • 0029744020 scopus 로고    scopus 로고
    • Pharmacokinetics of aztreonam and imipenem in critically ill patients with pneumonia
    • McKindley DS, Boucher BA, Hess MM, Croce MA, Fabian TC. Pharmacokinetics of aztreonam and imipenem in critically ill patients with pneumonia. Pharmacotherapy, 1996;16:924-931.
    • (1996) Pharmacotherapy , vol.16 , pp. 924-931
    • McKindley, D.S.1    Boucher, B.A.2    Hess, M.M.3    Croce, M.A.4    Fabian, T.C.5
  • 34
    • 0034978302 scopus 로고    scopus 로고
    • Pharmacokinetic population study to describe cefepime lung concentrations
    • Breilh D, Saux M-C, Delaisement C, et al. Pharmacokinetic population study to describe cefepime lung concentrations. Pulm Pharmacol Ther. 2001;14:69-74.
    • (2001) Pulm Pharmacol Ther , vol.14 , pp. 69-74
    • Breilh, D.1    Saux, M.-C.2    Delaisement, C.3
  • 35
    • 0041778291 scopus 로고    scopus 로고
    • Steady-state plasma and intrapulmonary concentrations of cefepime administered in continuous infusion in critically ill patients with severe nosocomial pneumonia
    • Boselli E, Breilh D, Duflo F, et al. Steady-state plasma and intrapulmonary concentrations of cefepime administered in continuous infusion in critically ill patients with severe nosocomial pneumonia. Crit Care Med. 2003;31:2102-2106.
    • (2003) Crit Care Med , vol.31 , pp. 2102-2106
    • Boselli, E.1    Breilh, D.2    Duflo, F.3
  • 37
  • 39
    • 0347989421 scopus 로고    scopus 로고
    • Levofloxacin: A review of its use in the treatment of bacterial infections in the United States
    • Groom KF, Goa KL. Levofloxacin: a review of its use in the treatment of bacterial infections in the United States. Drugs, 2003;63:2769-2802.
    • (2003) Drugs , vol.63 , pp. 2769-2802
    • Groom, K.F.1    Goa, K.L.2
  • 40
    • 0030864108 scopus 로고    scopus 로고
    • Pharmacokinetic profile of levofloxacin following once-daily 500-milligram oral or intravenous doses
    • Chien S-C, Rogge MC, Gisclon LG, et al. Pharmacokinetic profile of levofloxacin following once-daily 500-milligram oral or intravenous doses. Antimicrob Agents Chemother. 1997;41:2256-2260.
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 2256-2260
    • Chien, S.-C.1    Rogge, M.C.2    Gisclon, L.G.3
  • 43
    • 0242385488 scopus 로고    scopus 로고
    • Relevance of soft-tissue penetration by levofloxacin for target site bacterial killing in patients with sepsis
    • Zeitlinger MA, Dehghanyar P, Mayer BX, et al. Relevance of soft-tissue penetration by levofloxacin for target site bacterial killing in patients with sepsis. Antimicrob Agents Chemother. 2003;47:3548-3553.
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 3548-3553
    • Zeitlinger, M.A.1    Dehghanyar, P.2    Mayer, B.X.3
  • 44
    • 0038172602 scopus 로고    scopus 로고
    • In vitro evaluation of the activity of two doses of levofloxacin alone and in combination with other agents against Pseudmonas aeruginosa
    • Burgess DS, Hall RG, Hardin TC. In vitro evaluation of the activity of two doses of levofloxacin alone and in combination with other agents against Pseudmonas aeruginosa. Diagn Microbiol Infect Dis. 2003;46:131-137.
    • (2003) Diagn Microbiol Infect Dis , vol.46 , pp. 131-137
    • Burgess, D.S.1    Hall, R.G.2    Hardin, T.C.3
  • 45
    • 0034007045 scopus 로고    scopus 로고
    • Pharmacokinetics and burn eschar penetration of intravenous ciprofloxacin in patients with major thermal injuries
    • Varela JE, Cohn SM, Brown M, Ward CG, Namias N, Spalding PB. Pharmacokinetics and burn eschar penetration of intravenous ciprofloxacin in patients with major thermal injuries. J Antimicrob Chemother. 2000;45:337-342.
    • (2000) J Antimicrob Chemother , vol.45 , pp. 337-342
    • Varela, J.E.1    Cohn, S.M.2    Brown, M.3    Ward, C.G.4    Namias, N.5    Spalding, P.B.6
  • 46
    • 1642362414 scopus 로고    scopus 로고
    • Steady-state intrapulmonary concentrations of moxifloxacin, levofloxacin, and azithromycin in older adults
    • Capitano B, Mattoes HM, Shore E, et al. Steady-state intrapulmonary concentrations of moxifloxacin, levofloxacin, and azithromycin in older adults. Chest. 2004;125:965-973.
    • (2004) Chest , vol.125 , pp. 965-973
    • Capitano, B.1    Mattoes, H.M.2    Shore, E.3
  • 48
    • 0242552187 scopus 로고    scopus 로고
    • Linezolid vs vancomycin: Analysis of two double-blind studies of patients with methicillin-resistant Staphylococcus aureus nosocomial pneumonia
    • Wunderink RG, Rello J, Cammarata SK, Croos-Dabrera RV, Kollef MH. Linezolid vs vancomycin: analysis of two double-blind studies of patients with methicillin-resistant Staphylococcus aureus nosocomial pneumonia. Chest. 2003;124:1789-1797.
    • (2003) Chest , vol.124 , pp. 1789-1797
    • Wunderink, R.G.1    Rello, J.2    Cammarata, S.K.3    Croos-Dabrera, R.V.4    Kollef, M.H.5
  • 51
    • 0032956432 scopus 로고    scopus 로고
    • Pharmacokinetic considerations in obesity
    • Blouin RA, Warren GW. Pharmacokinetic considerations in obesity. J Pharm Sci. 1999;88:1-7.
    • (1999) J Pharm Sci , vol.88 , pp. 1-7
    • Blouin, R.A.1    Warren, G.W.2
  • 53
    • 0029957068 scopus 로고    scopus 로고
    • Molecular mechanisms of drug metabolism in the critically ill
    • Park GR. Molecular mechanisms of drug metabolism in the critically ill. Br J Anaesth. 1996;77:32-49.
    • (1996) Br J Anaesth , vol.77 , pp. 32-49
    • Park, G.R.1
  • 54
    • 0032929747 scopus 로고    scopus 로고
    • The effects of erythromycin on the electrocardiogram
    • Mishra A, Friedman HS, Sinha AK. The effects of erythromycin on the electrocardiogram. Chest. 1999;115:983-986.
    • (1999) Chest , vol.115 , pp. 983-986
    • Mishra, A.1    Friedman, H.S.2    Sinha, A.K.3
  • 55
    • 0034800656 scopus 로고    scopus 로고
    • Seizures associated with fluoroquinolones
    • Kushner J, Peckman H, Snyder C. Seizures associated with fluoroquinolones. Ann Pharmacother, 2001;35:1194-1198.
    • (2001) Ann Pharmacother , vol.35 , pp. 1194-1198
    • Kushner, J.1    Peckman, H.2    Snyder, C.3
  • 57
    • 0036218554 scopus 로고    scopus 로고
    • Changes in plasma protein binding have little clinical relevance
    • Benet LZ, Hoener B-A. Changes in plasma protein binding have little clinical relevance. Clin Pharmacol Ther. 2002;71:115-121.
    • (2002) Clin Pharmacol Ther , vol.71 , pp. 115-121
    • Benet, L.Z.1    Hoener, B.-A.2
  • 58
    • 0024316006 scopus 로고
    • Protein binding: What does it mean?
    • Scheife RT. Protein binding: what does it mean? Drug Intell Clin Pharm. 1989;23:S27-S31.
    • (1989) Drug Intell Clin Pharm , vol.23
    • Scheife, R.T.1
  • 59
  • 60
    • 0023151322 scopus 로고
    • Decreased hepatic clearance of clindamycin in critically ill patients with sepsis
    • Mann HJ, Townsend RJ, Fuhs DW, Cerra FB. Decreased hepatic clearance of clindamycin in critically ill patients with sepsis. Clin Pharm. 1987;6:154-159.
    • (1987) Clin Pharm , vol.6 , pp. 154-159
    • Mann, H.J.1    Townsend, R.J.2    Fuhs, D.W.3    Cerra, F.B.4
  • 62
    • 0025042945 scopus 로고
    • Gentamicin volume of distribution in critically ill septic patients
    • Triginer C, Izquierdo I, Fernandez R, et al. Gentamicin volume of distribution in critically ill septic patients. Intensive Care Med. 1990;16:303-306.
    • (1990) Intensive Care Med , vol.16 , pp. 303-306
    • Triginer, C.1    Izquierdo, I.2    Fernandez, R.3
  • 63
    • 0017089571 scopus 로고
    • Increased dosage requirements of gentamicin in burn patients
    • Zaske DE, Sawchuk RJ, Gerding DN, Strate RG. Increased dosage requirements of gentamicin in burn patients. J Trauma. 1976;16:824-828.
    • (1976) J Trauma , vol.16 , pp. 824-828
    • Zaske, D.E.1    Sawchuk, R.J.2    Gerding, D.N.3    Strate, R.G.4
  • 66
    • 0030755852 scopus 로고    scopus 로고
    • The pharmacokinetics of intravenous ciprofloxacin 400 mg 12 hourly in patients with severe sepsis: The effect of renal function and intra-abdominal disease
    • Jones EM, McMullin CM, Hedges AJ, et al. The pharmacokinetics of intravenous ciprofloxacin 400 mg 12 hourly in patients with severe sepsis: the effect of renal function and intra-abdominal disease. J Antimicrob Chemother. 1997;40:121-124.
    • (1997) J Antimicrob Chemother , vol.40 , pp. 121-124
    • Jones, E.M.1    McMullin, C.M.2    Hedges, A.J.3
  • 67
    • 0035478070 scopus 로고    scopus 로고
    • Risks factors for Acinetobacter baumanii nosocomial bacteremia in critically ill patients: A cohort study
    • Garcia-Garmendia J-L, Ortiz-Leyba C, Garnacho-Montero J, et al. Risks factors for Acinetobacter baumanii nosocomial bacteremia in critically ill patients: a cohort study. Clin Infect Dis. 2001;33:939-946.
    • (2001) Clin Infect Dis , vol.33 , pp. 939-946
    • Garcia-Garmendia, J.-L.1    Ortiz-Leyba, C.2    Garnacho-Montero, J.3
  • 68
    • 0025669180 scopus 로고
    • Killing and regrowth of bacteria in vitro: A review
    • Craig WA, Ebert SC. Killing and regrowth of bacteria in vitro: a review. Scand J Infect Dis. 1991;74:63S-70S.
    • (1991) Scand J Infect Dis , vol.74
    • Craig, W.A.1    Ebert, S.C.2
  • 70
    • 0031952586 scopus 로고    scopus 로고
    • Pharmacokinetic/pharmacodynamic parameters: Rationale for antibacterial dosing of mice and men
    • Craig WA. Pharmacokinetic/pharmacodynamic parameters: rationale for antibacterial dosing of mice and men. Clin Infect Dis. 1998;26:1-12.
    • (1998) Clin Infect Dis , vol.26 , pp. 1-12
    • Craig, W.A.1
  • 71
    • 0141430942 scopus 로고    scopus 로고
    • Use of Monte Carlo simulation to design an optimized pharmacodynamic dosing strategy for meropenem
    • Kuti JL, Dandekar PK, Nightingale CH, Nicolau DP. Use of Monte Carlo simulation to design an optimized pharmacodynamic dosing strategy for meropenem. J Clin Pharmacol. 2003;43:1116-1123.
    • (2003) J Clin Pharmacol , vol.43 , pp. 1116-1123
    • Kuti, J.L.1    Dandekar, P.K.2    Nightingale, C.H.3    Nicolau, D.P.4
  • 72
    • 0036744992 scopus 로고    scopus 로고
    • Pharmacodymamic profiling of continuously infused piperacillin/tazobactam against Pseudomonas aeruginosa using Monte Carlo analysis
    • Kuti JL, Nightingale CH, Quintiliani R, Nicolau DP. Pharmacodymamic profiling of continuously infused piperacillin/tazobactam against Pseudomonas aeruginosa using Monte Carlo analysis. Diagn Microbiol Infect Dis. 2002;44:51-57.
    • (2002) Diagn Microbiol Infect Dis , vol.44 , pp. 51-57
    • Kuti, J.L.1    Nightingale, C.H.2    Quintiliani, R.3    Nicolau, D.P.4
  • 73
    • 0034006869 scopus 로고    scopus 로고
    • Cerebrospinal fluid penetration and pharmacokinetics of vancomycin administered by continuous infusion to mechanically ventilated patients in an intensive care unit
    • Albanese J, Leone M, Bruguerolle B, Ayem M-L, Lacarelle B, Martin C. Cerebrospinal fluid penetration and pharmacokinetics of vancomycin administered by continuous infusion to mechanically ventilated patients in an intensive care unit. Antimicrob Agents Chemother. 2000;44:1356-1358.
    • (2000) Antimicrob Agents Chemother , vol.44 , pp. 1356-1358
    • Albanese, J.1    Leone, M.2    Bruguerolle, B.3    Ayem, M.-L.4    Lacarelle, B.5    Martin, C.6


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