Induction of apoptosis in human oral cancer cell lines, OC2 and TSCCa, by Chingwaysan

American Journal of Chinese Medicine

Volumn 33, Issue 1, 2005, Pages 21-27

  Liao, Pao Hsin ^a   Chen, Shiow Ling ^a   Shih, Hung Che ^a   Chou, Ming Yung ^a  

^a CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Apoptosis; Bax protein; Chingwaysan; Cimicfugae Rhizoma; DNA fragmentation; Moutan Radicis Cortex; Rehmanniae Radixet Rhizoma

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ANGELICA ROOT; ANGELICA SINENSIS EXTRACT; CHINESE DRUG; CHINGWAYSAN; CIMICIFUGA RHIZOMA EXTRACT; COPTIS RHIZOME; DNA FRAGMENT; HERBACEOUS AGENT; MOUTAN EXTRACT; PAEONIA SUFFRUTICOSA EXTRACT; PROTEIN BAX; REHMANNIA EXTRACT; UNCLASSIFIED DRUG;

AGAR GEL ELECTROPHORESIS; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL VIABILITY; CHEEK MUCOSA; CHINESE HERB; CIMICIFUGA; COMPUTER PROGRAM; CONTROLLED STUDY; DNA DEGRADATION; GINGIVA BLEEDING; HUMAN; HUMAN CELL; MOUTH CANCER; MOUTH ULCER; PAEONIA SUFFRUTICOSA; REHMANNIA; TOOTH PAIN;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL DIVISION; CELL LINE, TUMOR; DRUGS, CHINESE HERBAL; ELECTROPHORESIS, AGAR GEL; FIBROBLASTS; GENE EXPRESSION; GINGIVA; HUMANS; MOUTH NEOPLASMS; PROTO-ONCOGENE PROTEINS C-BCL-2; REHMANNIA;

EID: 16344379958     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X0500262X     Document Type: Article

References (19)

1. Arends, M.J., R.G. Morris and A.H. Wyllie. The role of the endonuclease. Am. Pathol. 136: 593-608, 1990.
2. Barry, M.A., C.A. Belinke and A. Eastman. Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxins and hyperthermia. Biochem. Pharmacol. 40: 2353-2362, 1990.
3. Barry, M.A., J.E. Reynolds and A. Eastman. Etoposide-induced apoptosis in human HL-1360 cells is associated with intracellular acidification. Cancer Res. 53: 2349-2357, 1993.
4. Blagosklonny, M.V., R. Robey, S. Bates and T. Fojo. Pretreatment with DNA-damaging agents permits selective killing of checkpoint-deficient cells by microtubule-active drugs. J. Clin. Invest. 105: 533-539, 2000.
5. Brady, H.J.M. and G.G. Gabriel. Molecules in focus Bax. The pro-apoptotic Bcl-2 family member, bax. Int. J. Biochem. Cell Biol. 30: 647-650, 1998.
6. Brunelle, J.K. and N.S. Chandel. Oxygen deprivation induced cell death. Apoptosis 7: 475-482, 2002.
7. Brunelle, F.M. and R.K. Verbeeck. Glucoronidation of diflunisal by rat liver microsomes. Effect of microsomal beta-glucuronidase activity. Biochem. Pharmacol. 46(11): 1953-1958, 1993.
8. Buchholz, T.A., D.W. Davis, D.J. McConkey, W.F. Symmans, V. Valero, A.J. Hingran, S.L. Tucker, L. Pusztai, M. Cristofanilli, F.J. Esteva, G.N. Hortobagyi and A.A. Sahin. Chemotherapy-induced apoptosis and Bcl-2 levels correlate with breast cancer response to chemotherapy. Cancer J. 9: 33-41, 2003.
9. He, N.G., H.Q. Zhang, P.G. Song, Z.M. Liu and S.B. Xue. Mechanism of enhancement of bleomycin A5 antitumor activity by verapamil. Yao Hsueh Pao 26: 15-19, 1991 (in Chinese).
10. Herrmann, M., H.M. Lorenz, R. Voll, M. Grunke, W. Woith and J.R. Kalden. A rapid and simple method for the isolation of apoptotic DNA fragments. Nucleic Acid Res. 22: 5506-5507, 1994.
11. Hickman, J.A. Apoptosis induced by anticancer drugs. Cancer Metastasis Rev. 11: 121-139, 1992.
12. Hickman, A.B., D.C. Klein and F. Dyda. Melatonin biosynthesis: The structure of serotonin N-acetyltransferase at 2.5 A resolution suggests a catalytic mechanism. Mol. Cell. 3(1): 23-32, 1999.
13. Jin, H.X. Establishment of neck lymph node metastasis cell line derived from human oral squamous cell carcinoma and tongue squamous cell carcinoma cell line and analysis of their biological properties Doctoral Dissertation, 1997.
14. Tounekti, O., G. Pron, J. Belehradek and L.M. Mir. Bleomycin, an apoptosis-mimetic drug that induces two types of cell death depending on the number of molecules internalized. Cancer Res. 53: 5462-5469, 1993.
15. Umezawa, H., K. Maeda, T. Takeuchi and Y. Okami. New antibiotics, bleomycin A and B. J. Antibiotics 19: 200-209, 1996.
16. Umezawa, H., T. Takeuchi, S. Hori, T. Sawa and M. Ishizuka. Studies on the mechanism of antitumor effect of bleomycin on squamous cell carcinoma. J. Antibiotics 25: 409-420, 1972.
17. Wong, D.Y.K., K.W. Chang, C.F. Chen and R.C.S. Chang. Characterization of two new cell lines derived from oral cavity human squamous cell carcinoma-OC1 and OC2. J. Oral Maxillofac. Surg. 48: 385-390, 1990.
18. Wyllie, A.H., J.F.R. Kerr and A.R. Currie. Cell death: The significance of apoptosis. Int. Rev. Cytol. 68: 251-356, 1980.
19. Xue, S.B., Z.H. Cheng, H.T. Liu, et al. Effects of bleomycin A5 on cell cycle of Chinese hamster ovary cell. Chung Kuo Yao Li Hsueh Pao 5: 112-114, 1984 (in Chinese).