A quantitative genomic expression analysis platform for multiplexed in vitro prediction of drug action

Pharmacogenomics Journal

Volumn 5, Issue 2, 2005, Pages 126-134

  Gunther, Erik C ^a,c   Stone, D J ^a,b   Rothberg, J M ^a   Gerwien, R W ^a  

^a CURAGEN CORPORATION   (United States)

^b ROSETTA INPHARMATICS   (United States)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Drug discovery; Efficacy profiling; Fingerprinting; Predictive efficacy; Supervised classification

Indexed keywords

ACETYLSALICYLIC ACID; ALPRAZOLAM; BIOLOGICAL MARKER; CARBAMAZEPINE; CLOMIPRAMINE; COMPACTIN; DIAZEPAM; DILTIAZEM; DYNORPHIN A; ENKEPHALIN; ETHOSUXIMIDE; FELBAMATE; FLURAZEPAM; FLURBIPROFEN; GABAPENTIN; IBUPROFEN; INDOMETACIN; MEVINOLIN; NIFEDIPINE; NIGULDIPINE; NIMODIPINE; NITRENDIPINE; PHENYTOIN; RILUZOLE; UNINDEXED DRUG; VALPROIC ACID; VERAPAMIL; VIGABATRIN; ZOLPIDEM; ZOPICLONE;

ACCURACY; ANALGESIA; ANTICONVULSANT ACTIVITY; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; BRAIN CELL; CELL CULTURE; CELL FUNCTION; CELL LINE; COMPUTER PROGRAM; CONTROLLED STUDY; DRUG ACTIVITY; DRUG CLASSIFICATION; DRUG MECHANISM; DRUG RESEARCH; DRUG RESPONSE; DRUG TARGETING; ENZYME INHIBITION; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; IN VITRO STUDY; PHARMACOGENOMICS; PREDICTION; PRIORITY JOURNAL; PROTEIN MICROARRAY; QUANTITATIVE ANALYSIS;

ALGORITHMS; ARTIFICIAL INTELLIGENCE; CELL LINE; DATA INTERPRETATION, STATISTICAL; DNA, COMPLEMENTARY; GENE EXPRESSION; GENETIC MARKERS; HUMANS; MODELS, STATISTICAL; NEURONS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHARMACEUTICAL PREPARATIONS; PHARMACOLOGY; PREDICTIVE VALUE OF TESTS;

EID: 16344370951     PISSN: 1470269X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.tpj.6500300     Document Type: Article

References (12)

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