Positive association of RhoC gene overexpression with tumour invasion and lymphatic metastasis in gastric carcinoma

Chinese Medical Journal

Volumn 118, Issue 6, 2005, Pages 502-504

  Wang, Zheng Ning ^a   Xu, Hui Mian ^a   Jiang, Li ^a   Zhou, Xin ^a   Lu, Chong ^a   Zhang, Xue ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Gastric carcinoma; Invasion; Metastasis; RhoC gene

Indexed keywords

GUANOSINE TRIPHOSPHATASE;

ARTICLE; CANCER INVASION; CANCER PATIENT; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GASTRECTOMY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; LASER CAPTURE MICRODISSECTION; LYMPH NODE DISSECTION; LYMPH NODE METASTASIS; MALE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; STOMACH CARCINOMA; TISSUE SECTION;

FEMALE; HUMANS; LYMPHATIC METASTASIS; MALE; MICRODISSECTION; NEOPLASM INVASIVENESS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RHO GTP-BINDING PROTEINS; RNA, MESSENGER; STOMACH NEOPLASMS;

EID: 16344369239     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Clark EA, Golub TR, Lander ES, et al. Genomic analysis of metastasis reveals an essential role for RhoC. Nature 2000;406:532-535.
2. Wang ZN, Xu HM, Jiang L, et al. Expression of survivin in primary and metastatic gastric cancer cells obtained by laser capture microdissection. World J Gastroenterol 2004;10:3094-3098.
3. Kleer CG, Van Golen KL, Zhang Y, et al. Characterization of RhoC expression in benign and malignant breast disease: a potential new marker for small breast carcinomas with metastatic ability. Am J Pathol 2002;160:579-584.
4. Suwa H, Ohshio G, Imamura T, et al. Overexpression of the RhoC gene correlates with progression of ductal adenocarcinoma of the pancreas. Br J Cancer 1998; 77:147-152.
5. Kondo T, Sentani K, Oue N, et al. Expression of RHOC is associated with metastasis of gastric carcinomas. Pathobiology 2004;71:19-25.