Synthesis, molecular structure, and in vitro antitumor activity of new 4-chloro-2-mercaptobenzenesulfonamide derivatives

European Journal of Medicinal Chemistry

Volumn 40, Issue 4, 2005, Pages 377-389

  Sławiński, Jarosław ^a   Gdaniec, Maria ^b  

^a MEDICAL UNIVERSITY OF GDANSK   (Poland)

^b ADAM MICKIEWICZ UNIVERSITY   (Poland)

Author keywords

4 Chloro 2 mercapto N (1,2,4 triazin 3 yl)benzenesulfonamide; Antitumor effect; Crystal structures; Synthesis

Indexed keywords

1 (2 BENZYLTHIO 4 CHLORO 5 PHENYLCARBAMOYLBENZENESULFONYL) 3 (2 OXOBUTAN 3 YLIDENEIMINO)GUANIDINE; 1 (4 CHLORO 5 METHYL 2 METHYLTHIOBENZENESULFONYL) 3 (2 OXOBUTAN 3 YLIDENEIMINO)GUANIDINE; 2 BENZYLTHIO 4 CHLORO 5 (4 CHLOROPHENYLCARBAMOYL) N (5,6 DIPHENYL 1,2,4 TRIAZIN 3 YL)BENZENESULFONAMIDE; 2 BENZYLTHIO 4 CHLORO 5 (4 METHYLPHENYLCARBAMOYL) N (5,6 DIPHENYL 1,2,4 TRIAZIN 3 YL)BENZENESULFONAMIDE; 2 BENZYLTHIO 4 CHLORO 5 CYANO N (5,6 DIPHENYL 1,2,4 TRIAZIN 3 YL)BENZENESULFONAMIDE; 2 BENZYLTHIO 4 CHLORO 5 METHYL N (1,2 DIHYDROXYCYCLOBUTA[E] 1,2,4 TRIAZIN 3 YL)BENZENESULFONAMIDE; 2 BENZYLTHIO 4 CHLORO 5 METHYL N (5,6 DIFURYL 1,2,4 TRIAZIN 3 YL)BENZENESULFONAMIDE; 2 BENZYLTHIO 4 CHLORO 5 METHYL N (5,6 DIPHENYL 1,2,4 TRIAZIN 3 YL)BENZENESULFONAMIDE; 2 BENZYLTHIO 4 CHLORO 5 PHENYLCARBAMOYL N (5,6 DIPHENYL 1,2,4 TRIAZIN 3 YL)BENZENESULFONAMIDE; 2 BENZYLTHIO 5 CARBAMOYL 4 CHLORO N (5,6 DIPHENYL 1,2,4 TRIAZIN 3 YL)BENZENESULFONAMIDE; 2 BENZYLTHIO 5 CARBAMOYL 4 CHLORO N [5,6 DI(2 FURYL) 1,2,4 TRIAZIN 3 YL]BENZENESULFONAMIDE; 2 CARBAMOLYMETHYLTHIO 4 CHLORO 5 METHYL N (5,6 DIPHENYL 1,2,4 TRIAZIN 3 YL)BENZENESULFONAMIDE; SULFONAMIDE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CENTER; COLON CANCER; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; KIDNEY CANCER; LUNG NON SMALL CELL CANCER; MELANOMA; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE; X RAY ANALYSIS;

EID: 16244421723     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejmech.2004.11.014     Document Type: Article

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