1-Oxabicyclic β-lactams as new inhibitors of elongating MPT-a key enzyme responsible for assembly of cell-surface phosphoglycans of Leishmania parasite

Organic and Biomolecular Chemistry

Volumn 3, Issue 6, 2005, Pages 1043-1048

  Ruhela, Dipali ^a   Chatterjee, Patrali ^a   Vishwakarma, Ram A ^a  

^a JAWAHARLAL NEHRU UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOLS; BIOLOGICAL MEMBRANES; BIOSYNTHESIS; CELLS; DISEASES; DRUG PRODUCTS; ENZYME INHIBITION; ENZYMES; OLIGOMERS; PHOSPHOLIPIDS; VACCINES;

CELL-SURFACE PHOSPHOGLYCANS; GALACTOSYLTRANSFERASE (GALT) ENZYMES; MEMBRANE-BOUND LIPOPHOSPOHOGLYCAN (LPG); PROTEOPHOSPHOGLYCAN (PPG);

CARBOHYDRATES;

BETA LACTAM; ELONGATING ALPHA D MANOSYL PHOSPHOSPHATE TRANSFERASE; ELONGATING ALPHA-D-MANOSYL PHOSPHOSPHATE TRANSFERASE; ENZYME INHIBITOR; GLYCOSPHINGOLIPID; LIPOPHOSPHOGLYCAN; PHOSPHOTRANSFERASE; POLYSACCHARIDE;

ANIMAL; ARTICLE; CELL SURVIVAL; CHEMISTRY; CONFORMATION; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; LEISHMANIA; LEISHMANIASIS; METABOLISM; SYNTHESIS;

ANIMALS; BETA-LACTAMS; CARBOHYDRATE CONFORMATION; CELL SURVIVAL; ENZYME INHIBITORS; GLYCOSPHINGOLIPIDS; LEISHMANIA; LEISHMANIASIS; POLYSACCHARIDES; TRANSFERASES (OTHER SUBSTITUTED PHOSPHATE GROUPS);

EID: 16244417456     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/b418247b     Document Type: Article

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